UniProt P68036
Ubiquitin-conjugating enzyme E2 L3 (P68036)
Ubiquitin-conjugating enzyme E2 L3 (UniProt P68036): 27 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P68036
- Protein
- Ubiquitin-conjugating enzyme E2 L3
- Experimental structures
- 27
- Predicted models
- 1
- Ligands
- 2
Structures
28 records of P68036 in the MolNFT archive: 27 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1C4Z | Structure of an E6AP-UBCH7 complex: insights into the ubiquitination pathway | x-ray diffraction | D | — | — |
| 1C4Z | Structure of an E6AP-UBCH7 complex: insights into the ubiquitination pathway | x-ray diffraction | D | — | — |
| 1FBV | Structure of a cbl-UBCH7 complex: ring domain function in ubiquitin-protein ligases | x-ray diffraction | C | — | — |
| 1FBV | Structure of a cbl-UBCH7 complex: ring domain function in ubiquitin- protein ligases | x-ray diffraction | C | — | — |
| 3SQV | Crystal Structure of E. coli O157:H7 E3 ubiquitin ligase, NleL, with a human E2, UbcH7 | x-ray diffraction | C, D | — | — |
| 3SQV | Crystal structure of E. COLI O157:H7 E3 ubiquitin ligase, nlel, with a human E2, UBCH7 | x-ray diffraction | C, D | — | — |
| 3SY2 | Crystal structure of the Salmonella E3 ubiquitin ligase SopA in complex with the human E2 UbcH7 | x-ray diffraction | C, D | — | — |
| 3SY2 | Crystal structure of the salmonella E3 ubiquitin ligase sopa in complex with the human E2 UBCH7 | x-ray diffraction | C, D | — | — |
| 4Q5E | Shigella Effector Kinase OspG bound to E2-Ub UbcH7-Ub Conjugate | x-ray diffraction | C | — | — |
| 4Q5E | Shigella effector kinase ospg bound to E2-ub UBCH7-ub conjugate | x-ray diffraction | C | — | — |
| 4Q5H | Shigella Effector Kinase OspG bound to AMPPNP and E2-Ub UbcH7-Ub Conjugate | x-ray diffraction | C | — | — |
| 4Q5H | Shigella effector kinase ospg bound to amppnp and E2-ub UBCH7-ub conjugate | x-ray diffraction | C | — | — |
| 5HPT | System-wide modulation of hect E3 ligases with selective ubiquitin variant probes: WWP1, ubv P2.3… | x-ray diffraction | C, F | — | — |
| 5TTE | Crystal structure of an rbr E3 ubiquitin ligase in complex with an E2- ub thioester intermediate… | x-ray diffraction | E | — | — |
| 5UDH | HHARI/ARIH1-UBCH7~UBIQUITIN | x-ray diffraction | C, D | — | — |
| 6CP2 | Sidc in complex with UBCH7~UB | x-ray diffraction | B | — | — |
| 6DJW | Crystal structure of pparkin (rep and RING2 deleted)-pub-UBCH7 complex | x-ray diffraction | C | — | — |
| 6DJX | Crystal Structure of pParkin-pUb-UbcH7 complex | x-ray diffraction | C | — | — |
| 6DJX | Crystal structure of pparkin-pub-UBCH7 complex | x-ray diffraction | C | — | — |
| 6N13 | UBCH7-ub complex with R0RBR parkin and phosphoubiquitin | solution nmr | C | — | — |
| 6XXU | Solution NMR structure of the native form of UBCH7 (UBE2L3) | solution nmr | A | — | — |
| 7B5L | Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly… | electron microscopy | D | SY8 | — |
| 7B5L | Ubiquitin ligation to F-box protein substrates by scf-rbr E3-E3 super- assembly… | electron microscopy | D | SY8 | — |
| 7B5N | Ubiquitin ligation to F-box protein substrates by scf-rbr E3-E3 super- assembly… | electron microscopy | D | SY8 | — |
| 7OIK | Mouse RNF213:UBE2L3 transthiolation intermediate, chemically stabilized | electron microscopy | B | — | — |
| 7OIK | Mouse RNF213:UBE2L3 transthiolation intermediate, chemically stabilized | electron microscopy | B | — | — |
| 7V8F | Crystal structure of UBE2L3 bound to hoip RING1 domain. | x-ray diffraction | A | ZN | — |
| P68036 | AlphaFold monomer V2.0 prediction for ubiquitin-conjugating enzyme E2 L3 (P68036) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4Q5E chain C against the predicted model P68036: TM-score 0.99, RMSD 0.32 Å
- 4Q5E chain C against the predicted model P68036: TM-score 0.99, RMSD 0.32 Å
- 4Q5H chain C against the predicted model P68036: TM-score 0.99, RMSD 0.33 Å
- 4Q5H chain C against the predicted model P68036: TM-score 0.99, RMSD 0.33 Å
- 5TTE chain E against the predicted model P68036: TM-score 0.98, RMSD 0.61 Å
- 7OIK chain B against the predicted model P68036: TM-score 0.98, RMSD 0.56 Å
- 7OIK chain B against the predicted model P68036: TM-score 0.98, RMSD 0.56 Å
- 5UDH chain C against the predicted model P68036: TM-score 0.98, RMSD 0.61 Å
- 6N13 chain C against the predicted model P68036: TM-score 0.98, RMSD 0.73 Å
- 5UDH chain D against the predicted model P68036: TM-score 0.97, RMSD 0.63 Å
Elsewhere
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