UniProt P61024
Cyclin-dependent kinases regulatory subunit 1 (P61024)
Cyclin-dependent kinases regulatory subunit 1 (UniProt P61024): 18 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P61024
- Protein
- Cyclin-dependent kinases regulatory subunit 1
- Experimental structures
- 18
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 1 · 1 record with a druggable one
Structures
19 records of P61024 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1BUH | Crystal structure of the human CDK2 kinase complex with cell cycle-regulatory protein CKSHS1 | x-ray diffraction | B | — | — |
| 1BUH | Crystal structure of the human CDK2 kinase complex with cell cycle-regulatory protein CKSHS1 | x-ray diffraction | B | — | — |
| 1DKS | CKSHS1: human cyclin dependent kinase subunit, type 1 in complex with phosphate | x-ray diffraction | A, B | — | — |
| 1DKS | CKSHS1: human cyclin dependent kinase subunit, type 1 in complex with phosphate | x-ray diffraction | A, B | — | — |
| 1DKT | CKSHS1: human cyclin dependent kinase subunit, type 1 complex with metavanadate | x-ray diffraction | A, B | — | — |
| 1DKT | CKSHS1: human cyclin dependent kinase subunit, type 1 complex with metavanadate | x-ray diffraction | A, B | — | — |
| 2ASS | Crystal structure of the Skp1-Skp2-Cks1 complex | x-ray diffraction | C | — | — |
| 2ASS | Crystal structure of the SKP1-SKP2-CKS1 complex | x-ray diffraction | C | — | — |
| 2AST | Crystal structure of Skp1-Skp2-Cks1 in complex with a p27 peptide | x-ray diffraction | C | — | — |
| 2AST | Crystal structure of SKP1-SKP2-CKS1 in complex with a P27 peptide | x-ray diffraction | C | — | — |
| 4YC6 | CDK1/CKS1 | x-ray diffraction | B, D, F, H | — | — |
| 4YC6 | CDK1/CKS1 | x-ray diffraction | B, D, F, H | — | — |
| 7B5L | Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly… | electron microscopy | K | — | — |
| 7B5L | Ubiquitin ligation to F-box protein substrates by scf-rbr E3-E3 super- assembly… | electron microscopy | K | — | — |
| 7B5M | Ubiquitin ligation to F-box protein substrates by scf-rbr E3-E3 super- assembly… | electron microscopy | K | — | — |
| 7B5R | Ubiquitin ligation to F-box protein substrates by scf-rbr E3-E3 super- assembly… | electron microscopy | K | — | — |
| 7NJ0 | Cryoem structure of the human separase-CDK1-cyclin B1-CKS1 complex | electron microscopy | D | PO4 | — |
| 8OR0 | CAND1-CUL1-RBX1-SKP1-SKP2-CKS1-CDK2 | electron microscopy | G | — | 1 (best 0.71) |
| P61024 | AlphaFold monomer V2.0 prediction for cyclin-dependent kinases regulatory subunit 1 (P61024) | predicted | A | — | — |
Ligands
- PO4 · Phosphate ion · in 1 record
Experiment against prediction
- 2AST chain C against the predicted model P61024: TM-score 0.98, RMSD 0.42 Å
- 2AST chain C against the predicted model P61024: TM-score 0.98, RMSD 0.42 Å
- 2ASS chain C against the predicted model P61024: TM-score 0.98, RMSD 0.42 Å
- 2ASS chain C against the predicted model P61024: TM-score 0.98, RMSD 0.42 Å
- 7B5L chain K against the predicted model P61024: TM-score 0.96, RMSD 0.57 Å
- 7B5L chain K against the predicted model P61024: TM-score 0.96, RMSD 0.57 Å
- 1BUH chain B against the predicted model P61024: TM-score 0.96, RMSD 0.70 Å
- 1BUH chain B against the predicted model P61024: TM-score 0.96, RMSD 0.70 Å
- 7B5R chain K against the predicted model P61024: TM-score 0.95, RMSD 0.66 Å
- 4YC6 chain H against the predicted model P61024: TM-score 0.95, RMSD 0.69 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.