UniProt P0CG48
Polyubiquitin-C (P0CG48)
Polyubiquitin-C (UniProt P0CG48): 266 experimental structures on GenesisL1, 18 ligands bound, 78 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P0CG48
- Protein
- Polyubiquitin-C
- Experimental structures
- 266
- Predicted models
- 0
- Ligands
- 18
- Pockets
- 78 · 15 records with a druggable one
Structures
266 records of P0CG48 in the MolNFT archive: 266 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1OGW | Synthetic Ubiquitin with fluoro-Leu at 50 and 67 | x-ray diffraction | A | — | — |
| 1OGW | Synthetic ubiquitin with fluoro-leu at 50 and 67 | x-ray diffraction | A | — | — |
| 2L3Z | Proton-Detected 4D DREAM Solid-State NMR Structure of Ubiquitin | solid-state nmr | A | — | — |
| 2L3Z | Proton-detected 4D dream solid-state NMR structure of ubiquitin | solid-state nmr | A | — | — |
| 2LD9 | Backbone Structure of Ubiquitin determined using Backbone amide NOEs and Backbone N-H and N-C RDCs | solution nmr | A | — | — |
| 2LD9 | Backbone structure of ubiquitin determined using backbone amide noes and backbone N-H and N-C rdcs | solution nmr | A | — | — |
| 2LVO | Structure of the gp78CUE domain bound to monubiquitin | solution nmr | A | — | — |
| 2LVO | Structure of the GP78CUE domain bound to monubiquitin | solution nmr | A | — | — |
| 2LVP | gp78CUE domain bound to the distal ubiquitin of K48-linked diubiquitin | solution nmr | A, B | — | — |
| 2LVP | GP78CUE domain bound to the distal ubiquitin of K48-linked diubiquitin | solution nmr | A, B | — | — |
| 2LVQ | gp78CUE domain bound to the proximal ubiquitin of K48-linked diubiquitin | solution nmr | A, B | — | — |
| 2LVQ | GP78CUE domain bound to the proximal ubiquitin of K48-linked diubiquitin | solution nmr | A, B | — | — |
| 2LZ6 | Distinct ubiquitin binding modes exhibited by sh3 domains: molecular determinants and functional… | solution nmr | A | — | — |
| 2LZ6 | Distinct ubiquitin binding modes exhibited by SH3 domains: molecular determinants and functional… | solution nmr | A | — | — |
| 2MBO | K11-linked Diubiquitin average solution structure at pH 6.8, 0 mM NaCl | solution nmr | A, B | — | — |
| 2MBO | K11-linked diubiquitin average solution structure at pH 6.8, 0 mm nacl | solution nmr | A, B | — | — |
| 2MBQ | K11-linked Diubiquitin average solution structure at pH 6.8, 150 mM NaCl | solution nmr | A, B | — | — |
| 2MBQ | K11-linked diubiquitin average solution structure at pH 6.8, 150 mm nacl | solution nmr | A, B | — | — |
| 2MCN | Distinct ubiquitin binding modes exhibited by SH3 domains: molecular determinants and functional… | solution nmr | B | — | — |
| 2MCN | Distinct ubiquitin binding modes exhibited by SH3 domains: molecular determinants and functional… | solution nmr | B | — | — |
| 2MI8 | Solution structure of lysine-free (K0) ubiquitin | solution nmr | A | — | — |
| 2MI8 | Solution structure of lysine-free (K0) ubiquitin | solution nmr | A | — | — |
| 2MJ5 | Structure of the UBA Domain of Human NBR1 in Complex with Ubiquitin | solution nmr | A | — | — |
| 2MJ5 | Structure of the uba domain of human NBR1 in complex with ubiquitin | solution nmr | A | — | — |
| 2MOR | A tensor-free method for the structural and dynamical refinement of proteins using residual dipolar… | solution nmr | A | — | — |
| 2MOR | A tensor-free method for the structural and dynamical refinement of proteins using residual dipolar… | solution nmr | A | — | — |
| 2MRE | NMR structure of the Rad18-UBZ/ubiquitin complex | solution nmr | A | — | — |
| 2MRE | NMR structure of the RAD18-UBZ/UBIQUITIN complex | solution nmr | A | — | — |
| 2MWS | Structure of the complex of ubiquitin and the ubiquitin-like (UBL) domain of Ddi1 | solution nmr | A | — | — |
| 2MWS | Structure of the complex of ubiquitin and the ubiquitin-like (ubl) domain of DDI1 | solution nmr | A | — | — |
| 2N2K | Ensemble structure of the closed state of Lys63-linked diubiquitin in the absence of a ligand | solution nmr | A, B | — | — |
| 2N2K | Ensemble structure of the closed state of LYS63-linked diubiquitin in the absence of a ligand | solution nmr | A, B | — | — |
| 2RR9 | The solution structure of the K63-Ub2:tUIMs complex | solution nmr | A, B | — | — |
| 2RR9 | The solution structure of the K63-UB2:TUIMS complex | solution nmr | A, B | — | — |
| 2RSU | Alternative structure of Ubiquitin | solution nmr | A | — | — |
| 2RSU | Alternative structure of ubiquitin | solution nmr | A | — | — |
| 2RU6 | The pure alternative state of ubiquitin | solution nmr | A | — | — |
| 2RU6 | The pure alternative state of ubiquitin | solution nmr | A | — | — |
| 3ALB | Cyclic Lys48-linked tetraubiquitin | x-ray diffraction | A, B, C, D | — | — |
| 3ALB | Cyclic LYS48-linked tetraubiquitin | x-ray diffraction | A, B, C, D | — | — |
| 3AUL | Crystal structure of wild-type Lys48-linked diubiquitin in an open conformation | x-ray diffraction | A, B | — | — |
| 3AUL | Crystal structure of wild-type LYS48-linked diubiquitin in an open conformation | x-ray diffraction | A, B | — | — |
| 3B08 | Crystal structure of the mouse HOIL1-L-NZF in complex with linear di-ubiquitin | x-ray diffraction | A, D, G, J | — | — |
| 3B08 | Crystal structure of the mouse HOIL1-L-nzf in complex with linear di- ubiquitin | x-ray diffraction | A, D, G, J | — | — |
| 3B0A | Crystal structure of the mouse HOIL1-L-NZF in complex with linear di-ubiquitin | x-ray diffraction | A, D | — | — |
| 3B0A | Crystal structure of the mouse HOIL1-L-nzf in complex with linear di- ubiquitin | x-ray diffraction | A, D | — | — |
| 3OFI | Crystal structure of human insulin-degrading enzyme in complex with ubiquitin | x-ray diffraction | C, D | — | — |
| 3OFI | Crystal structure of human insulin-degrading enzyme in complex with ubiquitin | x-ray diffraction | C, D | — | — |
| 3PRM | Structural analysis of a viral otu domain protease from the crimean- congo hemorrhagic fever virus… | x-ray diffraction | B, D | — | — |
| 3Q3F | Engineering Domain-Swapped Binding Interfaces by Mutually Exclusive Folding: Insertion of Ubiquitin… | x-ray diffraction | A | — | — |
| 3Q3F | Engineering domain-swapped binding interfaces by mutually exclusive folding: insertion of ubiquitin… | x-ray diffraction | A | — | — |
| 3RUL | New strategy to analyze structures of glycopeptide-target complexes | x-ray diffraction | A, B, C, D | — | — |
| 3RUL | New strategy to analyze structures of glycopeptide-target complexes | x-ray diffraction | A, B, C, D | — | — |
| 3TMP | The catalytic domain of human deubiquitinase DUBA in complex with ubiquitin aldehyde | x-ray diffraction | B, D, F, H | — | — |
| 3TMP | The catalytic domain of human deubiquitinase duba in complex with ubiquitin aldehyde | x-ray diffraction | B, D, F, H | — | — |
| 3U30 | Crystal structure of a linear-specific Ubiquitin fab bound to linear ubiquitin | x-ray diffraction | A, D | — | — |
| 3U30 | Crystal structure of a linear-specific ubiquitin Fab bound to linear ubiquitin | x-ray diffraction | A, D | — | — |
| 3UGB | UbcH5c~Ubiquitin Conjugate | x-ray diffraction | B | — | — |
| 3UGB | UBCH5C~UBIQUITIN conjugate | x-ray diffraction | B | — | — |
| 3V6C | Crystal Structure of USP2 in complex with mutated ubiquitin | x-ray diffraction | B | — | — |
206 records more on the page itself.
Ligands
- ZN · Zinc ion · in 10 records
- SO4 · Sulfate ion · in 8 records
- SY8 · 5-azanylpentan-2-one · in 4 records
- AR6 · [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl [hydroxy-[[(2R,3S,4R,5S)-3,4,5-trihydroxyoxolan-2-yl]methoxy]phosphoryl] hydrogen phosphate · in 2 records
- LWZ · 3,3-bis(sulfanyl)-~{N}-(1~{H}-1,2,3-triazol-4-ylmethyl)propanamide · in 2 records
- NAD · Nicotinamide-adenine-dinucleotide · in 2 records
- NEH · Ethanamine · in 2 records
- PO4 · Phosphate ion · in 2 records
- 3CN · 3-aminopropane · in 1 record
- AYE · prop-2-en-1-amine · in 1 record
- BR · Bromide ion · in 1 record
- GVE · Methyl 4-aminobutanoate · in 1 record
- IOD · Iodide ion · in 1 record
- K · Potassium ion · in 1 record
- LI · Lithium ion · in 1 record
- MG · Magnesium ion · in 1 record
- NA · Sodium ion · in 1 record
- NO3 · Nitrate ion · in 1 record
Experiment against prediction
- 3Q3F chain A against the predicted model P00648: TM-score 0.54, RMSD 1.12 Å
- 7R70 chain A against the predicted model Q6ZSG1: TM-score 0.52, RMSD 2.24 Å
- 7R71 chain A against the predicted model Q6ZSG1: TM-score 0.50, RMSD 2.04 Å
- 7R71 chain A against the predicted model Q6ZSG1: TM-score 0.50, RMSD 2.04 Å
- 7R70 chain B against the predicted model Q6ZSG1: TM-score 0.49, RMSD 2.40 Å
Elsewhere
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