UniProt P63208
S-phase kinase-associated protein 1 (P63208)
S-phase kinase-associated protein 1 (UniProt P63208): 68 experimental structures on GenesisL1, 23 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P63208
- Protein
- S-phase kinase-associated protein 1
- Experimental structures
- 68
- Predicted models
- 0
- Pockets
- 23 · 5 records with a druggable one
Structures
68 records of P63208 in the MolNFT archive: 68 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1FQV | Insights into scf ubiquitin ligases from the structure of the skp1-skp2 complex | x-ray diffraction | B, D, F, H, J, L, N, P | — | — |
| 1FQV | Insights into scf ubiquitin ligases from the structure of the SKP1-SKP2 complex | x-ray diffraction | B, D, F, H, J, L, N, P | — | — |
| 1FS1 | Insights into scf ubiquitin ligases from the structure of the SKP1-SKP2 complex | x-ray diffraction | B, D | — | — |
| 1FS1 | Insights into scf ubiquitin ligases from the structure of the SKP1-SKP2 complex | x-ray diffraction | B, D | — | — |
| 1FS2 | Insights into scf ubiquitin ligases from the structure of the SKP1-SKP2 complex | x-ray diffraction | B, D | — | — |
| 1FS2 | Insights into scf ubiquitin ligases from the structure of the SKP1-SKP2 complex | x-ray diffraction | B, D | — | — |
| 1LDK | Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF Ubiquitin Ligase Complex | x-ray diffraction | D | — | — |
| 1LDK | Structure of the CUL1-RBX1-SKP1-F BOXSKP2 scf ubiquitin ligase complex | x-ray diffraction | D | — | — |
| 1P22 | Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine… | x-ray diffraction | B | — | — |
| 1P22 | Structure of a beta-TRCP1-SKP1-beta-catenin complex: destruction motif binding and lysine… | x-ray diffraction | B | — | — |
| 2ASS | Crystal structure of the Skp1-Skp2-Cks1 complex | x-ray diffraction | A | — | — |
| 2ASS | Crystal structure of the SKP1-SKP2-CKS1 complex | x-ray diffraction | A | — | — |
| 2AST | Crystal structure of Skp1-Skp2-Cks1 in complex with a p27 peptide | x-ray diffraction | A | — | — |
| 2AST | Crystal structure of SKP1-SKP2-CKS1 in complex with a P27 peptide | x-ray diffraction | A | — | — |
| 2E31 | Structural basis for selection of glycosylated substrate by SCFFbs1 ubiquitin ligase | x-ray diffraction | B | — | — |
| 2E31 | Structural basis for selection of glycosylated substrate by SCFFBS1 ubiquitin ligase | x-ray diffraction | B | — | — |
| 2E32 | Structural basis for selection of glycosylated substrate by SCFFbs1 ubiquitin ligase | x-ray diffraction | B, D | — | — |
| 2E32 | Structural basis for selection of glycosylated substrate by SCFFBS1 ubiquitin ligase | x-ray diffraction | B, D | — | — |
| 2OVP | Structure of the Skp1-Fbw7 complex | x-ray diffraction | A | — | — |
| 2OVP | Structure of the SKP1-FBW7 complex | x-ray diffraction | A | — | — |
| 2OVQ | Structure of the Skp1-Fbw7-CyclinEdegC complex | x-ray diffraction | A | — | — |
| 2OVQ | Structure of the SKP1-FBW7-cyclinedegc complex | x-ray diffraction | A | — | — |
| 2OVR | Structure of the Skp1-Fbw7-CyclinEdegN complex | x-ray diffraction | A | — | — |
| 2OVR | Structure of the SKP1-FBW7-cyclinedegn complex | x-ray diffraction | A | — | — |
| 3L2O | Structure-Based Mechanism of Dimerization-Dependent Ubiquitination by the SCFFbx4 Ubiquitin Ligase | x-ray diffraction | A | — | — |
| 3L2O | Structure-based mechanism of dimerization-dependent ubiquitination by the SCFFBX4 ubiquitin ligase | x-ray diffraction | A | — | — |
| 3WSO | Crystal structure of the Skp1-FBG3 complex | x-ray diffraction | B | — | — |
| 3WSO | Crystal structure of the SKP1-FBG3 complex | x-ray diffraction | B | — | — |
| 4I6J | A ubiquitin ligase-substrate complex | x-ray diffraction | C | — | — |
| 4I6J | A ubiquitin ligase-substrate complex | x-ray diffraction | C | — | — |
| 5IBK | Skp1-F-box in complex with a ubiquitin variant | x-ray diffraction | A, D | — | — |
| 5IBK | SKP1-F-box in complex with a ubiquitin variant | x-ray diffraction | A, D | — | — |
| 5JH5 | Structural basis for the hierarchical assembly of the core of PRC1.1 | x-ray diffraction | B | — | — |
| 5K35 | Structure of the Legionella effector, AnkB, in complex with human Skp1 | x-ray diffraction | B | — | — |
| 5K35 | Structure of the legionella effector, ankb, in complex with human SKP1 | x-ray diffraction | B | — | — |
| 5V4B | Crystal structure of the Skp1-FBXW7-DISC1 complex | x-ray diffraction | A | — | 3 (best 0.80) |
| 5V4B | Crystal structure of the SKP1-FBXW7-DISC1 complex | x-ray diffraction | A | — | — |
| 5VZT | Crystal structure of the SKP1-FBXO31 complex | x-ray diffraction | A, C | — | — |
| 5VZU | Crystal structure of the SKP1-FBXO31-cyclin D1 complex | x-ray diffraction | A, C | — | — |
| 5XYL | Solution structure of SKP1 from homo sapiens | solution nmr | A | — | — |
| 6BVA | Ubiquitin variant (UBV.FL10.1) bound to a human SKP1-FBL10 fragment complex. | x-ray diffraction | D, C | — | — |
| 6BYH | Ubiquitin Variant (UbV.Fl11.1) bound to a human Skp1-Fbl11 fragment complex. | x-ray diffraction | A, B, G | — | 9 (best 0.60) |
| 6BYH | Ubiquitin variant (UBV.FL11.1) bound to a human SKP1-FBL11 fragment complex. | x-ray diffraction | A, B, G | — | — |
| 6C16 | Ubiquitin variant (UbV.Fbl10.1) bound to a human Skp1-Fbl11 fragment complex. | x-ray diffraction | A, B | — | — |
| 6C16 | Ubiquitin variant (UBV.FBL10.1) bound to a human SKP1-FBL11 fragment complex. | x-ray diffraction | A, B | — | — |
| 6M90 | Monophosphorylated PSER33 B-catenin peptide, B-TRCP/SKP1, nrx-2776 ternary complex | x-ray diffraction | B | — | — |
| 6M91 | Monophosphorylated PSER33 B-catenin peptide, B-TRCP/SKP1, nrx-103094 ternary complex | x-ray diffraction | B | — | — |
| 6M92 | Monophosphorylated PSER33 B-catenin peptide, B-TRCP/SKP1, nrx-2663 ternary complex | x-ray diffraction | B | — | — |
| 6M93 | Monophosphorylated PSER33 B-catenin peptide, B-TRCP/SKP1, nrx-1933 ternary complex | x-ray diffraction | B | — | — |
| 6M94 | Monophosphorylated pSer33 b-Catenin peptide bound to b-TrCP/Skp1 Complex | x-ray diffraction | B | — | — |
| 6M94 | Monophosphorylated PSER33 B-catenin peptide bound to B-TRCP/SKP1 complex | x-ray diffraction | B | — | — |
| 6O60 | Crystal structure of GGTASE3-FBXL2-SKP1 complex | x-ray diffraction | D | — | — |
| 6TTU | Ubiquitin ligation to substrate by a cullin-ring E3 ligase at 3.7A resolution: NEDD8-CUL1-RBX1… | electron microscopy | S | — | — |
| 6VCD | Cryo-EM structure of IRP2-FBXL5-SKP1 complex | electron microscopy | C | — | — |
| 6W66 | The structure of the F64A, S172A mutant KEAP1-btb domain in complex with SKP1-FBXL17 | x-ray diffraction | A | — | — |
| 6WCQ | Structure of a substrate-bound dqc ubiquitin ligase | electron microscopy | A | — | — |
| 6WNX | FBXW11-SKP1 in complex with a PSER33/PSER37 beta-catenin peptide | x-ray diffraction | B, E, H | — | — |
| 7B5L | Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly… | electron microscopy | S | — | — |
| 7B5L | Ubiquitin ligation to F-box protein substrates by scf-rbr E3-E3 super- assembly… | electron microscopy | S | — | — |
| 7B5M | Ubiquitin ligation to F-box protein substrates by scf-rbr E3-E3 super- assembly… | electron microscopy | S | — | — |
8 records more on the page itself.
Elsewhere
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