MolNFT v1 · #140790 · protein + RNA
Cryo-EM structure of the post-catalytic spliceosome from saccharomyces cerevisiae at 3.6 ångström
5YLZ: “Cryo-EM structure of the post-catalytic spliceosome from saccharomyces cerevisiae at 3.6 ångström”. Electron microscopy, 4 ligands (IHP, GTP, MG). MolNFT v1 #140790 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5YLZ
- Type
- protein + RNA
- Length
- 9,468 residues
- Chains
- 43
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P33334, P36048, Q06091, Q04048, Q12309, Q03654, P53277, P25337, P40968, P38241, Q12046, Q12417, Q03772, P28004, Q03375, P53333, P33411, Q02775, P24384, P40018, Q12330, P54999, P40204, P43321, Q02260, Q06217, Q08963, P40567, P32523
- Ligands
- IHP, GTP, MG, ZN
Structure
electron microscopy · 39 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 1931 | — | P33334 |
| B | — | rna | 117 | — | — |
| C | — | protein | 878 | — | P36048 |
| D | — | rna | 103 | — | — |
| E | — | rna | 62 | — | — |
| F | — | rna | 91 | — | — |
| G | — | protein | 156 | — | Q06091 |
| H | — | protein | 562 | — | Q04048 |
| I | — | protein | 517 | — | Q12309 |
| J | — | protein | 432 | — | Q03654 |
| K | — | protein | 96 | — | P53277 |
| L | — | protein | 157 | — | P25337 |
| T | — | protein | 344 | — | P40968 |
| M | — | protein | 185 | — | P38241 |
| N | — | protein | 261 | — | Q12046 |
| O | — | protein | 337 | — | Q12417 |
| P | — | protein | 69 | — | Q03772 |
| Q | — | protein | 201 | — | P28004 |
| R | — | protein | 27 | — | Q03375 |
| S | — | protein | 207 | — | P53333 |
| U | — | protein | 148 | — | P33411 |
| V | — | protein | 88 | — | Q02775 |
| W | — | protein | 703 | — | P24384 |
| a | — | protein | 80 | — | P40018 |
| b, i | — | protein | 75 | — | Q12330 |
| c, j | — | protein | 70 | — | P54999 |
| d, k | — | protein | 69 | — | P40204 |
| e | — | protein | 82 | — | P43321 |
| f, m | — | protein | 82 | — | Q02260 |
| g | — | protein | 94 | — | Q06217 |
| h | — | protein | 78 | — | P40018 |
| l | — | protein | 81 | — | P43321 |
| n | — | protein | 65 | — | Q06217 |
| o | — | protein | 135 | — | Q08963 |
| p | — | protein | 81 | — | P40567 |
| q | — | protein | 129 | — | P32523 |
| r | — | protein | 125 | — | P32523 |
| s | — | protein | 126 | — | P32523 |
| t | — | protein | 128 | — | P32523 |
Ligands and binding sites
- IHP · Inositol hexakisphosphate · ligand · chains A
- GTP · Guanosine-5'-triphosphate · ligand · chains A, C
- MG · Magnesium ion · metal · 6 copies · chains C, D, E
- ZN · Zinc ion · metal · 6 copies · chains L, M, N
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5YLZ · Cryo-EM Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae at 3.6… · the same entry in another collection · chain K against K, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P33334
- Every structure of UniProt P36048
- Every structure of UniProt Q06091
- Every structure of UniProt Q04048
- Every structure of UniProt Q12309
- Every structure of UniProt Q03654
- Every structure of UniProt P53277
- Every structure of UniProt P25337
- Every structure of UniProt P40968
- Every structure of UniProt P38241
- Every structure of UniProt Q12046
- Every structure of UniProt Q12417
- Every structure of UniProt Q03772
- Every structure of UniProt P28004
- Every structure of UniProt Q03375
- Every structure of UniProt P53333
- Every structure of UniProt P33411
- Every structure of UniProt Q02775
- Every structure of UniProt P24384
- Every structure of UniProt P40018
- Every structure of UniProt Q12330
- Every structure of UniProt P54999
- Every structure of UniProt P40204
- Every structure of UniProt P43321
- Every structure of UniProt Q02260
- Every structure of UniProt Q06217
- Every structure of UniProt Q08963
- Every structure of UniProt P40567
- Every structure of UniProt P32523
- Elsewhere: RCSB PDB 5YLZ · PDBe 5YLZ · UniProt P33334 · UniProt P36048 · UniProt Q06091 · UniProt Q04048 · UniProt Q12309 · UniProt Q03654 · UniProt P53277 · UniProt P25337 · UniProt P40968 · UniProt P38241 · UniProt Q12046 · UniProt Q12417 · UniProt Q03772 · UniProt P28004 · UniProt Q03375 · UniProt P53333 · UniProt P33411 · UniProt Q02775 · UniProt P24384 · UniProt P40018 · UniProt Q12330 · UniProt P54999 · UniProt P40204 · UniProt P43321 · UniProt Q02260 · UniProt Q06217 · UniProt Q08963 · UniProt P40567 · UniProt P32523
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