UniProt Q12330
Small nuclear ribonucleoprotein E (Q12330)
Small nuclear ribonucleoprotein E (UniProt Q12330): 44 experimental structures and 1 predicted model on GenesisL1, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q12330
- Protein
- Small nuclear ribonucleoprotein E
- Experimental structures
- 44
- Predicted models
- 1
- Pockets
- 11 · 7 records with a druggable one
Structures
45 records of Q12330 in the MolNFT archive: 44 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3JCM | Cryo-EM structure of the spliceosomal U4/U6.U5 tri-snRNP | electron microscopy | V, Y | — | — |
| 3JCM | Cryo-EM structure of the spliceosomal U4/U6.U5 tri-snrnp | electron microscopy | V, Y | — | — |
| 5GAM | Foot region of the yeast spliceosomal U4/U6.U5 tri-snRNP | electron microscopy | e | — | — |
| 5GAM | Foot region of the yeast spliceosomal U4/U6.U5 tri-snrnp | electron microscopy | e | — | — |
| 5GAN | The overall structure of the yeast spliceosomal U4/U6.U5 tri-snrnp at 3.7 ångström | electron microscopy | p, e | — | — |
| 5GAO | Head region of the yeast spliceosomal U4/U6.U5 tri-snrnp | electron microscopy | p | — | — |
| 5GMK | Cryo-EM structure of the catalytic step I spliceosome (C complex) at 3.4 ångström resolution | electron microscopy | i, u | — | — |
| 5LJ3 | Structure of the core of the yeast spliceosome immediately after branching | electron microscopy | e, p | — | — |
| 5LJ5 | Overall structure of the yeast spliceosome immediately after branching. | electron microscopy | e, p | — | — |
| 5LQW | yeast activated spliceosome | electron microscopy | e | — | — |
| 5LQW | Yeast activated spliceosome | electron microscopy | e | — | — |
| 5MPS | Structure of a spliceosome remodeled for exon ligation | electron microscopy | e | — | — |
| 5MQ0 | Structure of a spliceosome remodeled for exon ligation | electron microscopy | e, p | — | — |
| 5MQ0 | Structure of a spliceosome remodeled for exon ligation | electron microscopy | e, p | — | — |
| 5WSG | Cryo-EM structure of the Catalytic Step II spliceosome (C* complex) at 4.0 angstrom resolution | electron microscopy | i, G | — | — |
| 5WSG | Cryo-EM structure of the catalytic step II spliceosome (C* complex) at 4.0 ångström resolution | electron microscopy | i, G | — | — |
| 5Y88 | Cryo-EM structure of the intron-lariat spliceosome ready for disassembly from S.CEREVISIAE at 3.5… | electron microscopy | b, i | — | — |
| 5YLZ | Cryo-EM Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae at 3.6 angstrom | electron microscopy | b, i | — | — |
| 5YLZ | Cryo-EM structure of the post-catalytic spliceosome from saccharomyces cerevisiae at 3.6 ångström | electron microscopy | b, i | — | — |
| 5ZWN | Cryo-EM structure of the yeast pre-B complex at an average resolution of 3.3 angstrom (Part II: U1… | electron microscopy | e | — | — |
| 5ZWN | Cryo-EM structure of the yeast pre-B complex at an average resolution of 3.3 ångström (part II: U1… | electron microscopy | e | — | — |
| 5ZWO | Cryo-EM structure of the yeast B complex at average resolution of 3.9 ångström | electron microscopy | e, T, i | — | — |
| 6BK8 | S. cerevisiae spliceosomal post-catalytic P complex | electron microscopy | c, l | — | — |
| 6EXN | Post-catalytic P complex spliceosome with 3' splice site docked | electron microscopy | e, p | — | — |
| 6EXN | Post-catalytic P complex spliceosome with 3' splice site docked | electron microscopy | e, p | — | — |
| 6G90 | Prespliceosome structure provides insight into spliceosome assembly and regulation (MAP A2) | electron microscopy | e, w | — | — |
| 6J6G | Cryo-EM structure of the yeast B*-a2 complex at an average resolution of 3.2 angstrom | electron microscopy | u, i | — | 1 (best 0.79) |
| 6J6G | Cryo-EM structure of the yeast B*-A2 complex at an average resolution of 3.2 ångström | electron microscopy | u, i | — | — |
| 6J6H | Cryo-EM structure of the yeast B*-a1 complex at an average resolution of 3.6 angstrom | electron microscopy | u, i | — | 2 (best 0.79) |
| 6J6H | Cryo-EM structure of the yeast B*-A1 complex at an average resolution of 3.6 ångström | electron microscopy | u, i | — | — |
| 6J6N | Cryo-EM structure of the yeast B*-b1 complex at an average resolution of 3.86 angstrom | electron microscopy | u, i | — | 2 (best 0.80) |
| 6J6N | Cryo-EM structure of the yeast B*-B1 complex at an average resolution of 3.86 ångström | electron microscopy | u, i | — | — |
| 6J6Q | Cryo-EM structure of the yeast B*-b2 complex at an average resolution of 3.7 angstrom | electron microscopy | u, i | — | 1 (best 0.80) |
| 6J6Q | Cryo-EM structure of the yeast B*-B2 complex at an average resolution of 3.7 ångström | electron microscopy | u, i | — | — |
| 6N7P | S. cerevisiae spliceosomal E complex (UBC4) | electron microscopy | O | — | 2 (best 0.86) |
| 6N7P | S. cerevisiae spliceosomal E complex (UBC4) | electron microscopy | O | — | — |
| 6N7R | Saccharomyces cerevisiae spliceosomal E complex (ACT1) | electron microscopy | O | — | — |
| 6N7X | S. cerevisiae U1 snRNP | electron microscopy | O | — | 1 (best 0.85) |
| 6N7X | S. cerevisiae U1 snrnp | electron microscopy | O | — | — |
| 7B9V | Yeast C complex spliceosome at 2.8 Angstrom resolution with Prp18/Slu7 bound | electron microscopy | e, p | — | — |
| 7OQB | The U2 part of saccharomyces cerevisiae spliceosomal pre-a complex (delta bs-a ACT1) | electron microscopy | w | — | — |
| 7OQC | The U1 part of saccharomyces cerevisiae spliceosomal pre-a complex (delta bs-a ACT1) | electron microscopy | e | — | — |
| 7OQE | Saccharomyces cerevisiae spliceosomal pre-a complex (delta bs-a ACT1) | electron microscopy | e, w | — | — |
| 8W2O | Yeast U1 snRNP with humanized U1C Zinc-Finger domain | electron microscopy | O | — | 2 (best 0.83) |
| Q12330 | AlphaFold monomer V2.0 prediction for small nuclear ribonucleoprotein E (Q12330) | predicted | A | — | — |
Experiment against prediction
- 7B9V chain e against the predicted model Q12330: TM-score 0.96, RMSD 0.70 Å
- 5ZWO chain e against the predicted model Q12330: TM-score 0.95, RMSD 0.83 Å
- 3JCM chain V against the predicted model Q12330: TM-score 0.95, RMSD 0.85 Å
- 3JCM chain V against the predicted model Q12330: TM-score 0.95, RMSD 0.85 Å
- 6G90 chain w against the predicted model Q12330: TM-score 0.95, RMSD 1.00 Å
- 7OQE chain w against the predicted model Q12330: TM-score 0.95, RMSD 1.00 Å
- 7OQB chain w against the predicted model Q12330: TM-score 0.95, RMSD 1.00 Å
- 5ZWO chain T against the predicted model Q12330: TM-score 0.94, RMSD 1.01 Å
- 6EXN chain p against the predicted model Q12330: TM-score 0.94, RMSD 1.02 Å
- 6EXN chain p against the predicted model Q12330: TM-score 0.94, RMSD 1.02 Å
Elsewhere
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