UniProt P28004
Pre-mRNA-processing protein 45 (P28004)
Pre-mRNA-processing protein 45 (UniProt P28004): 24 experimental structures and 1 predicted model on GenesisL1, 32 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P28004
- Protein
- Pre-mRNA-processing protein 45
- Experimental structures
- 24
- Predicted models
- 1
- Pockets
- 32 · 5 records with a druggable one
Structures
25 records of P28004 in the MolNFT archive: 24 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5GMK | Cryo-EM structure of the catalytic step I spliceosome (C complex) at 3.4 ångström resolution | electron microscopy | P | — | — |
| 5LJ3 | Structure of the core of the yeast spliceosome immediately after branching | electron microscopy | K | — | — |
| 5LJ5 | Overall structure of the yeast spliceosome immediately after branching. | electron microscopy | K | — | — |
| 5LQW | yeast activated spliceosome | electron microscopy | M | — | — |
| 5LQW | Yeast activated spliceosome | electron microscopy | M | — | — |
| 5MPS | Structure of a spliceosome remodeled for exon ligation | electron microscopy | K | — | — |
| 5MQ0 | Structure of a spliceosome remodeled for exon ligation | electron microscopy | K | — | 7 (best 0.87) |
| 5MQ0 | Structure of a spliceosome remodeled for exon ligation | electron microscopy | K | — | — |
| 5WSG | Cryo-EM structure of the Catalytic Step II spliceosome (C* complex) at 4.0 angstrom resolution | electron microscopy | P | — | — |
| 5WSG | Cryo-EM structure of the catalytic step II spliceosome (C* complex) at 4.0 ångström resolution | electron microscopy | P | — | — |
| 5Y88 | Cryo-EM structure of the intron-lariat spliceosome ready for disassembly from S.CEREVISIAE at 3.5… | electron microscopy | Q | — | — |
| 5YLZ | Cryo-EM Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae at 3.6 angstrom | electron microscopy | Q | — | — |
| 5YLZ | Cryo-EM structure of the post-catalytic spliceosome from saccharomyces cerevisiae at 3.6 ångström | electron microscopy | Q | — | — |
| 6BK8 | S. cerevisiae spliceosomal post-catalytic P complex | electron microscopy | E | — | — |
| 6EXN | Post-catalytic P complex spliceosome with 3' splice site docked | electron microscopy | K | — | — |
| 6EXN | Post-catalytic P complex spliceosome with 3' splice site docked | electron microscopy | K | — | — |
| 6J6G | Cryo-EM structure of the yeast B*-a2 complex at an average resolution of 3.2 angstrom | electron microscopy | P | — | 7 (best 0.89) |
| 6J6G | Cryo-EM structure of the yeast B*-A2 complex at an average resolution of 3.2 ångström | electron microscopy | P | — | — |
| 6J6H | Cryo-EM structure of the yeast B*-a1 complex at an average resolution of 3.6 angstrom | electron microscopy | P | — | 5 (best 0.88) |
| 6J6H | Cryo-EM structure of the yeast B*-A1 complex at an average resolution of 3.6 ångström | electron microscopy | P | — | — |
| 6J6N | Cryo-EM structure of the yeast B*-b1 complex at an average resolution of 3.86 angstrom | electron microscopy | P | — | 5 (best 0.88) |
| 6J6N | Cryo-EM structure of the yeast B*-B1 complex at an average resolution of 3.86 ångström | electron microscopy | P | — | — |
| 6J6Q | Cryo-EM structure of the yeast B*-b2 complex at an average resolution of 3.7 angstrom | electron microscopy | P | — | 7 (best 0.87) |
| 6J6Q | Cryo-EM structure of the yeast B*-B2 complex at an average resolution of 3.7 ångström | electron microscopy | P | — | — |
| P28004 | AlphaFold monomer V2.0 prediction for pre-mRNA-processing protein 45 (P28004) | predicted | A | — | 1 (best 0.33) |
Experiment against prediction
- 5YLZ chain Q against the predicted model P28004: TM-score 0.63, RMSD 4.40 Å
- 5YLZ chain Q against the predicted model P28004: TM-score 0.63, RMSD 4.40 Å
- 5WSG chain P against the predicted model P28004: TM-score 0.62, RMSD 4.45 Å
- 5WSG chain P against the predicted model P28004: TM-score 0.62, RMSD 4.45 Å
- 5GMK chain P against the predicted model P28004: TM-score 0.62, RMSD 4.42 Å
- 6J6N chain P against the predicted model P28004: TM-score 0.62, RMSD 4.29 Å
- 6J6N chain P against the predicted model P28004: TM-score 0.62, RMSD 4.29 Å
- 5LQW chain M against the predicted model P28004: TM-score 0.62, RMSD 4.57 Å
- 5LQW chain M against the predicted model P28004: TM-score 0.62, RMSD 4.57 Å
- 6J6Q chain P against the predicted model P28004: TM-score 0.61, RMSD 4.64 Å
Elsewhere
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