UniProt Q03375
Pre-mRNA-splicing factor CWC21 (Q03375)
Pre-mRNA-splicing factor CWC21 (UniProt Q03375): 21 experimental structures and 1 predicted model on GenesisL1, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q03375
- Protein
- Pre-mRNA-splicing factor CWC21
- Experimental structures
- 21
- Predicted models
- 1
- Pockets
- 12 · 5 records with a druggable one
Structures
22 records of Q03375 in the MolNFT archive: 21 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5GMK | Cryo-EM structure of the catalytic step I spliceosome (C complex) at 3.4 ångström resolution | electron microscopy | J | — | — |
| 5LJ3 | Structure of the core of the yeast spliceosome immediately after branching | electron microscopy | R | — | — |
| 5LJ5 | Overall structure of the yeast spliceosome immediately after branching. | electron microscopy | R | — | — |
| 5MPS | Structure of a spliceosome remodeled for exon ligation | electron microscopy | R | — | — |
| 5MQ0 | Structure of a spliceosome remodeled for exon ligation | electron microscopy | R | — | 2 (best 0.83) |
| 5MQ0 | Structure of a spliceosome remodeled for exon ligation | electron microscopy | R | — | — |
| 5WSG | Cryo-EM structure of the Catalytic Step II spliceosome (C* complex) at 4.0 angstrom resolution | electron microscopy | J | — | — |
| 5WSG | Cryo-EM structure of the catalytic step II spliceosome (C* complex) at 4.0 ångström resolution | electron microscopy | J | — | — |
| 5YLZ | Cryo-EM Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae at 3.6 angstrom | electron microscopy | R | — | — |
| 5YLZ | Cryo-EM structure of the post-catalytic spliceosome from saccharomyces cerevisiae at 3.6 ångström | electron microscopy | R | — | — |
| 6BK8 | S. cerevisiae spliceosomal post-catalytic P complex | electron microscopy | K | — | — |
| 6EXN | Post-catalytic P complex spliceosome with 3' splice site docked | electron microscopy | R | — | — |
| 6EXN | Post-catalytic P complex spliceosome with 3' splice site docked | electron microscopy | R | — | — |
| 6J6G | Cryo-EM structure of the yeast B*-a2 complex at an average resolution of 3.2 angstrom | electron microscopy | J | — | 2 (best 0.89) |
| 6J6G | Cryo-EM structure of the yeast B*-A2 complex at an average resolution of 3.2 ångström | electron microscopy | J | — | — |
| 6J6H | Cryo-EM structure of the yeast B*-a1 complex at an average resolution of 3.6 angstrom | electron microscopy | J | — | 3 (best 0.89) |
| 6J6H | Cryo-EM structure of the yeast B*-A1 complex at an average resolution of 3.6 ångström | electron microscopy | J | — | — |
| 6J6N | Cryo-EM structure of the yeast B*-b1 complex at an average resolution of 3.86 angstrom | electron microscopy | J | — | 3 (best 0.88) |
| 6J6N | Cryo-EM structure of the yeast B*-B1 complex at an average resolution of 3.86 ångström | electron microscopy | J | — | — |
| 6J6Q | Cryo-EM structure of the yeast B*-b2 complex at an average resolution of 3.7 angstrom | electron microscopy | J | — | 2 (best 0.87) |
| 6J6Q | Cryo-EM structure of the yeast B*-B2 complex at an average resolution of 3.7 ångström | electron microscopy | J | — | — |
| Q03375 | AlphaFold monomer V2.0 prediction for pre-mRNA-splicing factor CWC21 (Q03375) | predicted | A | — | — |
Experiment against prediction
- 5YLZ chain R against the predicted model Q03375: TM-score 0.72, RMSD 1.74 Å
- 5YLZ chain R against the predicted model Q03375: TM-score 0.72, RMSD 1.74 Å
- 6J6N chain J against the predicted model Q03375: TM-score 0.71, RMSD 1.51 Å
- 6J6N chain J against the predicted model Q03375: TM-score 0.71, RMSD 1.51 Å
- 5GMK chain J against the predicted model Q03375: TM-score 0.70, RMSD 1.54 Å
- 6J6H chain J against the predicted model Q03375: TM-score 0.70, RMSD 1.48 Å
- 6J6H chain J against the predicted model Q03375: TM-score 0.70, RMSD 1.48 Å
- 6J6G chain J against the predicted model Q03375: TM-score 0.69, RMSD 1.43 Å
- 6J6G chain J against the predicted model Q03375: TM-score 0.69, RMSD 1.43 Å
- 6J6Q chain J against the predicted model Q03375: TM-score 0.69, RMSD 1.45 Å
Elsewhere
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