UniProt P24384
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22 (P24384)
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22 (UniProt P24384), EC 3.6.4.13: 7 experimental structures and 1 predicted model on GenesisL1, 18 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P24384
- Protein
- Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22
- EC
- 3.6.4.13
- Experimental structures
- 7
- Predicted models
- 1
- Pockets
- 18 · 2 records with a druggable one
Structures
8 records of P24384 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5MQ0 | Structure of a spliceosome remodeled for exon ligation | electron microscopy | V | — | 1 (best 0.78) |
| 5MQ0 | Structure of a spliceosome remodeled for exon ligation | electron microscopy | V | — | — |
| 5YLZ | Cryo-EM Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae at 3.6 angstrom | electron microscopy | W | — | — |
| 5YLZ | Cryo-EM structure of the post-catalytic spliceosome from saccharomyces cerevisiae at 3.6 ångström | electron microscopy | W | — | — |
| 6BK8 | S. cerevisiae spliceosomal post-catalytic P complex | electron microscopy | P | — | — |
| 6EXN | Post-catalytic P complex spliceosome with 3' splice site docked | electron microscopy | V | — | — |
| 6EXN | Post-catalytic P complex spliceosome with 3' splice site docked | electron microscopy | V | — | — |
| P24384 | AlphaFold monomer V2.0 prediction for pre-mRNA-splicing factor ATP- dependent RNA helicase PRP22… | predicted | A | — | 17 (best 0.78) |
Experiment against prediction
- 6EXN chain V against the predicted model P24384: TM-score 0.93, RMSD 2.74 Å
- 6EXN chain V against the predicted model P24384: TM-score 0.93, RMSD 2.74 Å
- 5MQ0 chain V against the predicted model P24384: TM-score 0.91, RMSD 2.59 Å
- 5MQ0 chain V against the predicted model P24384: TM-score 0.91, RMSD 2.59 Å
- 6BK8 chain P against the predicted model P24384: TM-score 0.90, RMSD 2.57 Å
- 5YLZ chain W against the predicted model P24384: TM-score 0.83, RMSD 3.63 Å
- 5YLZ chain W against the predicted model P24384: TM-score 0.83, RMSD 3.63 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.