UniProt P33411
Pre-mRNA-splicing factor 18 (P33411)
Pre-mRNA-splicing factor 18 (UniProt P33411): 13 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P33411
- Protein
- Pre-mRNA-splicing factor 18
- Experimental structures
- 13
- Predicted models
- 1
- Pockets
- 2 · 0 records with a druggable one
Structures
14 records of P33411 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1DVK | Crystal structure of the functional domain of the splicing factor PRP18 | x-ray diffraction | A, B | — | — |
| 1DVK | Crystal structure of the functional domain of the splicing factor PRP18 | x-ray diffraction | A, B | — | — |
| 5MPS | Structure of a spliceosome remodeled for exon ligation | electron microscopy | a | — | — |
| 5MPS | Structure of a spliceosome remodeled for exon ligation | electron microscopy | a | — | — |
| 5MQ0 | Structure of a spliceosome remodeled for exon ligation | electron microscopy | a | — | — |
| 5MQ0 | Structure of a spliceosome remodeled for exon ligation | electron microscopy | a | — | — |
| 5WSG | Cryo-EM structure of the Catalytic Step II spliceosome (C* complex) at 4.0 angstrom resolution | electron microscopy | f | — | — |
| 5WSG | Cryo-EM structure of the catalytic step II spliceosome (C* complex) at 4.0 ångström resolution | electron microscopy | f | — | — |
| 5YLZ | Cryo-EM Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae at 3.6 angstrom | electron microscopy | U | — | — |
| 5YLZ | Cryo-EM structure of the post-catalytic spliceosome from saccharomyces cerevisiae at 3.6 ångström | electron microscopy | U | — | — |
| 6BK8 | S. cerevisiae spliceosomal post-catalytic P complex | electron microscopy | N | — | — |
| 6EXN | Post-catalytic P complex spliceosome with 3' splice site docked | electron microscopy | a | — | — |
| 6EXN | Post-catalytic P complex spliceosome with 3' splice site docked | electron microscopy | a | — | — |
| P33411 | AlphaFold monomer V2.0 prediction for pre-mRNA-splicing factor 18 (P33411) | predicted | A | — | 2 (best 0.29) |
Experiment against prediction
- 5YLZ chain U against the predicted model P33411: TM-score 0.94, RMSD 1.43 Å
- 5YLZ chain U against the predicted model P33411: TM-score 0.94, RMSD 1.43 Å
- 5WSG chain f against the predicted model P33411: TM-score 0.94, RMSD 1.43 Å
- 5WSG chain f against the predicted model P33411: TM-score 0.94, RMSD 1.43 Å
- 5MQ0 chain a against the predicted model P33411: TM-score 0.94, RMSD 1.22 Å
- 5MQ0 chain a against the predicted model P33411: TM-score 0.94, RMSD 1.22 Å
- 5MPS chain a against the predicted model P33411: TM-score 0.94, RMSD 1.22 Å
- 5MPS chain a against the predicted model P33411: TM-score 0.94, RMSD 1.22 Å
- 1DVK chain B against the predicted model P33411: TM-score 0.94, RMSD 1.46 Å
- 1DVK chain B against the predicted model P33411: TM-score 0.94, RMSD 1.46 Å
Elsewhere
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