MolNFT v1 · #311070 · protein
AlphaFold monomer V2.0 prediction for pre-mRNA-splicing factor 18 (P33411)
P33411: “AlphaFold monomer V2.0 prediction for pre-mRNA-splicing factor 18 (P33411)”. 2 pockets (best druggability 0.29). MolNFT v1 #311070 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P33411
- Type
- protein
- Length
- 251 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x80D2ac0F5e3268bC5C1d28BBAA07E3169BB02b79
- Molecule
- Pre-mRNA-splicing factor 18
- UniProt
- P33411
- Pockets
- 2 · best druggability 0.29
Structure
1 distinct chain · 62% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pre-mRNA-splicing factor 18 | protein | 251 | 62% helix, 0% strand | P33411 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 64 | 0.29 | 0.74 | 17 | empty |
| 2 | 61 | 0.28 | 0.73 | 12 | empty |
Compared structures
- 1DVK · Crystal structure of the functional domain of the splicing factor PRP18 · an experimental structure of the same protein · chain A against B, TM-score 0.56
- 1DVK · Crystal structure of the functional domain of the splicing factor PRP18 · an experimental structure of the same protein · chain A against B, TM-score 0.56
- 5YLZ · Cryo-EM structure of the post-catalytic spliceosome from saccharomyces cerevisiae at 3.6… · an experimental structure of the same protein · chain A against U, TM-score 0.56
- 5YLZ · Cryo-EM Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae at 3.6… · an experimental structure of the same protein · chain A against U, TM-score 0.56
- 5WSG · Cryo-EM structure of the Catalytic Step II spliceosome (C* complex) at 4.0 angstrom… · an experimental structure of the same protein · chain A against f, TM-score 0.56
- 5WSG · Cryo-EM structure of the catalytic step II spliceosome (C* complex) at 4.0 ångström… · an experimental structure of the same protein · chain A against f, TM-score 0.56
- 6EXN · Post-catalytic P complex spliceosome with 3' splice site docked · an experimental structure of the same protein · chain A against a, TM-score 0.55
- 6EXN · Post-catalytic P complex spliceosome with 3' splice site docked · an experimental structure of the same protein · chain A against a, TM-score 0.55
- 6BK8 · S. cerevisiae spliceosomal post-catalytic P complex · an experimental structure of the same protein · chain A against N, TM-score 0.54
- 5MQ0 · Structure of a spliceosome remodeled for exon ligation · an experimental structure of the same protein · chain A against a, TM-score 0.53
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P33411
- Elsewhere: UniProt P33411 · AlphaFold DB P33411
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