UniProt Q03654
Pre-mRNA-splicing factor CEF1 (Q03654)
Pre-mRNA-splicing factor CEF1 (UniProt Q03654): 31 experimental structures and 1 predicted model on GenesisL1, 42 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q03654
- Protein
- Pre-mRNA-splicing factor CEF1
- Experimental structures
- 31
- Predicted models
- 1
- Pockets
- 42 · 12 records with a druggable one
Structures
32 records of Q03654 in the MolNFT archive: 31 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5GM6 | Cryo-EM structure of the activated spliceosome (Bact complex) at 3.5 angstrom resolution | electron microscopy | c | — | 3 (best 0.87) |
| 5GMK | Cryo-EM structure of the Catalytic Step I spliceosome (C complex) at 3.4 angstrom resolution | electron microscopy | c | — | 3 (best 0.89) |
| 5GMK | Cryo-EM structure of the catalytic step I spliceosome (C complex) at 3.4 ångström resolution | electron microscopy | c | — | — |
| 5LJ5 | Overall structure of the yeast spliceosome immediately after branching. | electron microscopy | O | — | 4 (best 0.88) |
| 5LJ5 | Overall structure of the yeast spliceosome immediately after branching. | electron microscopy | O | — | — |
| 5LQW | yeast activated spliceosome | electron microscopy | W | — | — |
| 5LQW | Yeast activated spliceosome | electron microscopy | W | — | — |
| 5MPS | Structure of a spliceosome remodeled for exon ligation | electron microscopy | O | — | 5 (best 0.89) |
| 5MPS | Structure of a spliceosome remodeled for exon ligation | electron microscopy | O | — | — |
| 5MQ0 | Structure of a spliceosome remodeled for exon ligation | electron microscopy | O | — | 4 (best 0.87) |
| 5MQ0 | Structure of a spliceosome remodeled for exon ligation | electron microscopy | O | — | — |
| 5WSG | Cryo-EM structure of the Catalytic Step II spliceosome (C* complex) at 4.0 angstrom resolution | electron microscopy | c | — | — |
| 5WSG | Cryo-EM structure of the catalytic step II spliceosome (C* complex) at 4.0 ångström resolution | electron microscopy | c | — | — |
| 5Y88 | Cryo-EM structure of the intron-lariat spliceosome ready for disassembly from S.cerevisiae at 3.5… | electron microscopy | J | — | 3 (best 0.89) |
| 5Y88 | Cryo-EM structure of the intron-lariat spliceosome ready for disassembly from S.CEREVISIAE at 3.5… | electron microscopy | J | — | — |
| 5YLZ | Cryo-EM Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae at 3.6 angstrom | electron microscopy | J | — | — |
| 5YLZ | Cryo-EM structure of the post-catalytic spliceosome from saccharomyces cerevisiae at 3.6 ångström | electron microscopy | J | — | — |
| 6BK8 | S. cerevisiae spliceosomal post-catalytic P complex | electron microscopy | S | — | 4 (best 0.88) |
| 6BK8 | S. cerevisiae spliceosomal post-catalytic P complex | electron microscopy | S | — | — |
| 6EXN | Post-catalytic P complex spliceosome with 3' splice site docked | electron microscopy | O | — | — |
| 6EXN | Post-catalytic P complex spliceosome with 3' splice site docked | electron microscopy | O | — | — |
| 6J6G | Cryo-EM structure of the yeast B*-a2 complex at an average resolution of 3.2 angstrom | electron microscopy | c | — | 4 (best 0.89) |
| 6J6G | Cryo-EM structure of the yeast B*-A2 complex at an average resolution of 3.2 ångström | electron microscopy | c | — | — |
| 6J6H | Cryo-EM structure of the yeast B*-a1 complex at an average resolution of 3.6 angstrom | electron microscopy | c | — | 3 (best 0.88) |
| 6J6H | Cryo-EM structure of the yeast B*-A1 complex at an average resolution of 3.6 ångström | electron microscopy | c | — | — |
| 6J6N | Cryo-EM structure of the yeast B*-b1 complex at an average resolution of 3.86 angstrom | electron microscopy | c | — | 2 (best 0.86) |
| 6J6N | Cryo-EM structure of the yeast B*-B1 complex at an average resolution of 3.86 ångström | electron microscopy | c | — | — |
| 6J6Q | Cryo-EM structure of the yeast B*-b2 complex at an average resolution of 3.7 angstrom | electron microscopy | c | — | 3 (best 0.87) |
| 6J6Q | Cryo-EM structure of the yeast B*-B2 complex at an average resolution of 3.7 ångström | electron microscopy | c | — | — |
| 7DCO | Cryo-EM structure of the activated spliceosome (Bact complex) at an atomic resolution of 2.5… | electron microscopy | L | — | — |
| 9DTR | Structure of the yeast post-catalytic P complex spliceosome at 2.3 Angstrom resolution | electron microscopy | O | — | 4 (best 0.88) |
| Q03654 | AlphaFold monomer V2.0 prediction for pre-mRNA-splicing factor CEF1 (Q03654) | predicted | A | — | — |
Experiment against prediction
- 6BK8 chain S against the predicted model Q03654: TM-score 0.94, RMSD 1.55 Å
- 6BK8 chain S against the predicted model Q03654: TM-score 0.94, RMSD 1.55 Å
- 5MQ0 chain O against the predicted model Q03654: TM-score 0.92, RMSD 1.68 Å
- 5MQ0 chain O against the predicted model Q03654: TM-score 0.92, RMSD 1.68 Å
- 5MPS chain O against the predicted model Q03654: TM-score 0.92, RMSD 1.68 Å
- 5MPS chain O against the predicted model Q03654: TM-score 0.92, RMSD 1.68 Å
- 5LQW chain W against the predicted model Q03654: TM-score 0.83, RMSD 1.92 Å
- 5LQW chain W against the predicted model Q03654: TM-score 0.83, RMSD 1.92 Å
- 6EXN chain O against the predicted model Q03654: TM-score 0.70, RMSD 1.63 Å
- 6EXN chain O against the predicted model Q03654: TM-score 0.70, RMSD 1.63 Å
Elsewhere
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