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MolNFT v1 · #172274 · protein + RNA

Cryo-EM structure of a late human pre-40S ribosomal subunit - state H2

6ZXH: “Cryo-EM structure of a late human pre-40S ribosomal subunit - state H2”. Electron microscopy, 4 ligands (ASP, ATP, MG). MolNFT v1 #172274 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6ZXH
Type
protein + RNA
Length
6,845 residues
Chains
36
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P08865, P61247, P15880, P62854, P62701, P23396, P62753, P62081, P62241, P46781, P46782, P62280, P46783, P62277, P62263, P25398, P62841, P08708, P62249, P62269, P39019, P63220, P62244, P62266, P62847, P60866, P62851, P42677, P62857, P62273, P62861, P62979, P63244, Q8N9N8, Q9BRS2
Ligands
ASP, ATP, MG, ZN

Structure

electron microscopy · 36 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
2—rna1651——
A—protein216—P08865
B—protein211—P61247
C—protein216—P15880
h—protein99—P62854
E—protein255—P62701
D—protein224—P23396
G—protein223—P62753
H—protein179—P62081
I—protein199—P62241
J—protein176—P46781
F—protein184—P46782
L—protein136—P62280
K—protein95—P46783
N—protein149—P62277
O—protein126—P62263
M—protein108—P25398
P—protein132—P62841
R—protein132—P08708
Q—protein140—P62249
S—protein141—P62269
T—protein141—P39019
V—protein83—P63220
W—protein129—P62244
X—protein139—P62266
Y—protein122—P62847
U—protein98—P60866
Z—protein82—P62851
b—protein77—P42677
c—protein61—P62857
d—protein54—P62273
e—protein50—P62861
f—protein57—P62979
g—protein295—P63244
j—protein116—Q8N9N8
z—protein349—Q9BRS2

Ligands and binding sites

  • ASP · Aspartic acid · ligand · chains 2, U, d
  • ATP · Adenosine-5'-triphosphate · ligand · chains 2, z
  • MG · Magnesium ion · metal · 131 copies · chains 2, T, I, h, z, O, N, U, Q, X, G, F, d
  • ZN · Zinc ion · metal · 3 copies · chains h, d, f

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6ZXH · Cryo-EM structure of a late human pre-40S ribosomal subunit - State H2 · the same entry in another collection · chain J against J, TM-score 1.00

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