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UniProt P62263

40S ribosomal protein S14 (P62263)

40S ribosomal protein S14 (UniProt P62263): 46 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 16 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
P62263
Protein
40S ribosomal protein S14
Experimental structures
46
Predicted models
1
Ligands
3
Pockets
16 · 11 records with a druggable one

Structures

47 records of P62263 in the MolNFT archive: 46 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
4UG0Structure of the human 80S ribosomeelectron microscopySO——
4V6XStructure of the human 80S ribosomeelectron microscopyAO——
5A2QStructure of the HCV ires bound to the human ribosomeelectron microscopyO——
5FLXMammalian 40S HCV-ires complexelectron microscopyO——
5LKSStructure-function insights reveal the human ribosome as a cancer target for antibioticselectron microscopySO——
5OA3Human 40S-EIF2D-re-initiation complexelectron microscopyO——
6G18Cryo-EM structure of a late human pre-40S ribosomal subunit - state Celectron microscopyO——
6G4SCryo-EM structure of a late human pre-40S ribosomal subunit - state Belectron microscopyO——
6G4WCryo-EM structure of a late human pre-40S ribosomal subunit - state aelectron microscopyO——
6G51Cryo-EM structure of a late human pre-40S ribosomal subunit - state Delectron microscopyO——
6G53Cryo-EM structure of a late human pre-40S ribosomal subunit - state Eelectron microscopyO——
6G5HCryo-EM structure of a late human pre-40S ribosomal subunit - matureelectron microscopyO——
6G5ICryo-EM structure of a late human pre-40S ribosomal subunit - state Relectron microscopyO——
6IP8Cryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv)electron microscopy3L——
6OLEHuman ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAselectron microscopySO——
6OLIStructure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule…electron microscopySO——
6YBDStructure of a human 48S translational initiation complex - EIF3electron microscopyP——
6YBWStructure of a human 48S translational initiation complex - 40S bodyelectron microscopyP—4 (best 0.87)
6YBWStructure of a human 48S translational initiation complex - 40S bodyelectron microscopyP——
6ZLWSARS-cov-2 NSP1 bound to the human 40S ribosomal subunitelectron microscopyP——
6ZMTSARS-cov-2 NSP1 bound to a pre-40S-like ribosome complexelectron microscopyP——
6ZN5SARS-cov-2 NSP1 bound to a pre-40S-like ribosome complex - state 2electron microscopyP——
6ZOJSARS-CoV-2-Nsp1-40S complex, composite mapelectron microscopyOMG—
6ZOJSARS-cov-2-NSP1-40S complex, composite MAPelectron microscopyOMG—
6ZOKSARS-cov-2-NSP1-40S complex, focused on bodyelectron microscopyOMG—
6ZUOHuman RIO1(KD)-stha late pre-40S particle, structural state a (pre 18S rRNA cleavage)electron microscopyO——
6ZV6Human RIO1(kd)-StHA late pre-40S particle, structural state B (post 18S rRNA cleavage)electron microscopyO—1 (best 0.90)
6ZV6Human RIO1(KD)-stha late pre-40S particle, structural state B (post 18S rRNA cleavage)electron microscopyO——
6ZVHEDF1-ribosome complexelectron microscopyOMG—
6ZXDCryo-EM structure of a late human pre-40S ribosomal subunit - state F1electron microscopyO——
6ZXECryo-EM structure of a late human pre-40S ribosomal subunit - state F2electron microscopyO——
6ZXFCryo-EM structure of a late human pre-40S ribosomal subunit - state Gelectron microscopyO——
6ZXGCryo-EM structure of a late human pre-40S ribosomal subunit - state H1electron microscopyOMG—
6ZXHCryo-EM structure of a late human pre-40S ribosomal subunit - state H2electron microscopyOMG—
7A09Structure of a human ABCE1-bound 43S pre-initiation complex - State IIIelectron microscopyi——
7K5ISARS-cov-2 NSP1 in complex with human 40S ribosomeelectron microscopyO——
7WTWCryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A3electron microscopyO—2 (best 0.86)
7WTXCryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-B1electron microscopyO—2 (best 0.88)
7XNXHigh resolution cry-EM structure of the human 80S ribosome from SNORD127+/+ Kasumi-1 cellselectron microscopySOMG1 (best 0.88)
7XNYHigh resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cellselectron microscopySOMG1 (best 0.86)
8G5YmRNA decoding in human is kinetically and structurally distinct from bacteria (IC state)electron microscopySOK, MG—
8G61mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state)electron microscopySOMG1 (best 0.86)
8K2CCryo-EM structure of the human 80S ribosome with Tigecyclineelectron microscopySOMG1 (best 0.88)
8PPKBat-Hp-CoV Nsp1 and eIF1 bound to the human 40S small ribosomal subunitelectron microscopyOUNX1 (best 0.88)
8PPLMERS-CoV Nsp1 bound to the human 43S pre-initiation complexelectron microscopyAOMG, UNX1 (best 0.88)
9G8Mhuman 80S ribosome bound by a SKI2-exosome complexelectron microscopySOMG1 (best 0.88)
P62263AlphaFold monomer V2.0 prediction for 40S ribosomal protein S14 (P62263)predictedA——

Ligands

  • MG · Magnesium ion · in 13 records
  • UNX · Unknown atom or ion · in 2 records
  • K · Potassium ion · in 1 record

Experiment against prediction

Elsewhere

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