UniProt P62273
40S ribosomal protein S29 (P62273)
40S ribosomal protein S29 (UniProt P62273): 75 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 82 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P62273
- Protein
- 40S ribosomal protein S29
- Experimental structures
- 75
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 82 · 42 records with a druggable one
Structures
76 records of P62273 in the MolNFT archive: 75 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4UG0 | Structure of the human 80S ribosome | electron microscopy | Sd | — | — |
| 4V6X | Structure of the human 80S ribosome | electron microscopy | Ad | — | — |
| 5A2Q | Structure of the HCV IRES bound to the human ribosome | electron microscopy | d | ZN | 3 (best 0.86) |
| 5A2Q | Structure of the HCV ires bound to the human ribosome | electron microscopy | d | — | — |
| 5FLX | Mammalian 40S HCV-IRES complex | electron microscopy | d | ZN | 3 (best 0.86) |
| 5FLX | Mammalian 40S HCV-ires complex | electron microscopy | d | — | — |
| 5LKS | Structure-function insights reveal the human ribosome as a cancer target for antibiotics | electron microscopy | Sd | ZN | — |
| 5OA3 | Human 40S-EIF2D-re-initiation complex | electron microscopy | d | ZN | — |
| 5VYC | Crystal structure of the human 40S ribosomal subunit in complex with DENR-MCT-1. | x-ray diffraction | d1, d2, d3, d4, d5, d6 | — | 6 (best 0.90) |
| 6G51 | Cryo-EM structure of a late human pre-40S ribosomal subunit - state D | electron microscopy | d | — | — |
| 6G53 | Cryo-EM structure of a late human pre-40S ribosomal subunit - state E | electron microscopy | d | — | — |
| 6G5H | Cryo-EM structure of a late human pre-40S ribosomal subunit - Mature | electron microscopy | d | ZN | 3 (best 0.82) |
| 6G5H | Cryo-EM structure of a late human pre-40S ribosomal subunit - mature | electron microscopy | d | ZN | — |
| 6G5I | Cryo-EM structure of a late human pre-40S ribosomal subunit - state R | electron microscopy | d | ZN | — |
| 6IP8 | Cryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv) | electron microscopy | 3E | — | — |
| 6OLE | Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAs | electron microscopy | Sd | — | — |
| 6OLF | Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAs | electron microscopy | Sd | — | 2 (best 0.88) |
| 6OLI | Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule… | electron microscopy | Sd | — | — |
| 6OM0 | Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE… | electron microscopy | Sd | — | 1 (best 0.87) |
| 6OM7 | Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and… | electron microscopy | Sd | — | 2 (best 0.86) |
| 6QZP | High-resolution cryo-EM structure of the human 80S ribosome | electron microscopy | Sd | MG, ZN | 1 (best 0.87) |
| 6XA1 | Structure of a drug-like compound stalled human translation termination complex | electron microscopy | Sd | ZN | 1 (best 0.87) |
| 6YBS | Structure of a human 48S translational initiation complex - head | electron microscopy | i | — | — |
| 6Z6L | Cryo-EM structure of human CCDC124 bound to 80S ribosomes | electron microscopy | Sd | ZN | 2 (best 0.86) |
| 6ZLW | SARS-cov-2 NSP1 bound to the human 40S ribosomal subunit | electron microscopy | f | ZN | — |
| 6ZMO | SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complex | electron microscopy | Sd | ZN | — |
| 6ZMT | SARS-CoV-2 Nsp1 bound to a pre-40S-like ribosome complex | electron microscopy | f | ZN | 3 (best 0.89) |
| 6ZMT | SARS-cov-2 NSP1 bound to a pre-40S-like ribosome complex | electron microscopy | f | ZN | — |
| 6ZN5 | SARS-cov-2 NSP1 bound to a pre-40S-like ribosome complex - state 2 | electron microscopy | f | ZN | — |
| 6ZOJ | SARS-CoV-2-Nsp1-40S complex, composite map | electron microscopy | d | ZN | — |
| 6ZOJ | SARS-cov-2-NSP1-40S complex, composite MAP | electron microscopy | d | ZN | — |
| 6ZOL | SARS-cov-2-NSP1-40S complex, focused on head | electron microscopy | d | ZN | — |
| 6ZON | SARS-CoV-2 Nsp1 bound to a human 43S preinitiation ribosome complex - state 1 | electron microscopy | l | ZN | 3 (best 0.88) |
| 6ZUO | Human RIO1(KD)-stha late pre-40S particle, structural state a (pre 18S rRNA cleavage) | electron microscopy | d | ZN | — |
| 6ZV6 | Human RIO1(kd)-StHA late pre-40S particle, structural state B (post 18S rRNA cleavage) | electron microscopy | d | — | 4 (best 0.84) |
| 6ZV6 | Human RIO1(KD)-stha late pre-40S particle, structural state B (post 18S rRNA cleavage) | electron microscopy | d | — | — |
| 6ZVH | EDF1-ribosome complex | electron microscopy | d | ZN | — |
| 6ZXD | Cryo-EM structure of a late human pre-40S ribosomal subunit - state F1 | electron microscopy | d | — | — |
| 6ZXE | Cryo-EM structure of a late human pre-40S ribosomal subunit - state F2 | electron microscopy | d | — | — |
| 6ZXF | Cryo-EM structure of a late human pre-40S ribosomal subunit - State G | electron microscopy | d | ZN | 2 (best 0.89) |
| 6ZXF | Cryo-EM structure of a late human pre-40S ribosomal subunit - state G | electron microscopy | d | ZN | — |
| 6ZXG | Cryo-EM structure of a late human pre-40S ribosomal subunit - state H1 | electron microscopy | d | ZN, MG | — |
| 6ZXH | Cryo-EM structure of a late human pre-40S ribosomal subunit - state H2 | electron microscopy | d | ASP, ZN, MG | — |
| 7A09 | Structure of a human ABCE1-bound 43S pre-initiation complex - State III | electron microscopy | l | ZN | — |
| 7K5I | SARS-cov-2 NSP1 in complex with human 40S ribosome | electron microscopy | d | ZN | — |
| 7QP6 | Structure of the human 48S initiation complex in open state (h48S AUG open) | electron microscopy | i | — | 4 (best 0.88) |
| 7QP7 | Structure of the human 48S initiation complex in closed state (h48S AUG closed) | electron microscopy | i | — | 2 (best 0.88) |
| 7XNX | High resolution cry-EM structure of the human 80S ribosome from SNORD127+/+ Kasumi-1 cells | electron microscopy | Sd | MG, ZN | 2 (best 0.89) |
| 7XNY | High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cells | electron microscopy | Sd | MG, ZN | 1 (best 0.86) |
| 8G5Y | mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state) | electron microscopy | Sd | ZN, MG | 1 (best 0.88) |
| 8G5Z | mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state) | electron microscopy | Sd | ZN, MG | 1 (best 0.88) |
| 8G60 | mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state) | electron microscopy | Sd | MG, ZN | 1 (best 0.88) |
| 8G61 | mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state) | electron microscopy | Sd | ZN | — |
| 8GLP | mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU… | electron microscopy | Sd | ZN, MG | — |
| 8IFD | Dibekacin-added human 80S ribosome | electron microscopy | 3E | — | 1 (best 0.88) |
| 8JDJ | Structure of the Human cytoplasmic Ribosome with human tRNA Asp(Q34) and mRNA(GAU) | electron microscopy | AP | ZN | 1 (best 0.86) |
| 8JDK | Structure of the Human cytoplasmic Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU) | electron microscopy | AP | ZN | 1 (best 0.87) |
| 8JDL | Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (non-rotated… | electron microscopy | AP | ZN | 1 (best 0.87) |
| 8K2C | Cryo-EM structure of the human 80S ribosome with Tigecycline | electron microscopy | Sd | ZN | 1 (best 0.87) |
| 8OZ0 | Structure of a human 48S translation initiation complex with eIF4F and eIF4A | electron microscopy | o | — | 2 (best 0.89) |
16 records more on the page itself.
Ligands
Experiment against prediction
- 6YBS chain i against the predicted model P62273: TM-score 0.96, RMSD 0.54 Å
- 8PJ6 chain i against the predicted model P62273: TM-score 0.95, RMSD 0.59 Å
- 8JDL chain AP against the predicted model P62273: TM-score 0.94, RMSD 0.61 Å
- 8PJ1 chain i against the predicted model P62273: TM-score 0.94, RMSD 0.63 Å
- 8G5Y chain Sd against the predicted model P62273: TM-score 0.94, RMSD 0.72 Å
- 8GLP chain Sd against the predicted model P62273: TM-score 0.94, RMSD 0.73 Å
- 8JDJ chain AP against the predicted model P62273: TM-score 0.94, RMSD 0.66 Å
- 8G60 chain Sd against the predicted model P62273: TM-score 0.93, RMSD 0.74 Å
- 8JDK chain AP against the predicted model P62273: TM-score 0.93, RMSD 0.64 Å
- 6ZMT chain f against the predicted model P62273: TM-score 0.93, RMSD 0.71 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.