UniProt Q9BRS2
Serine/threonine-protein kinase RIO1 (Q9BRS2)
Serine/threonine-protein kinase RIO1 (UniProt Q9BRS2), EC 2.7.11.1, 3.6.3.-: 16 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 22 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q9BRS2
- Protein
- Serine/threonine-protein kinase RIO1
- EC
- 2.7.11.1, 3.6.3.-
- Experimental structures
- 16
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 22 · 7 records with a druggable one
Structures
17 records of Q9BRS2 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4OTP | Crystal structure of the catalytic domain of the human RioK1 atypical protein kinase in complex… | x-ray diffraction | A | — | — |
| 4OTP | Crystal structure of the catalytic domain of the human RIOK1 atypical protein kinase in complex… | x-ray diffraction | A | — | — |
| 6G5I | Cryo-EM structure of a late human pre-40S ribosomal subunit - State R | electron microscopy | z | — | 1 (best 0.87) |
| 6G5I | Cryo-EM structure of a late human pre-40S ribosomal subunit - state R | electron microscopy | z | — | — |
| 6ZV6 | Human RIO1(kd)-StHA late pre-40S particle, structural state B (post 18S rRNA cleavage) | electron microscopy | h | ADP, MG | 1 (best 0.86) |
| 6ZV6 | Human RIO1(KD)-stha late pre-40S particle, structural state B (post 18S rRNA cleavage) | electron microscopy | h | ADP, MG | — |
| 6ZXD | Cryo-EM structure of a late human pre-40S ribosomal subunit - State F1 | electron microscopy | z | — | — |
| 6ZXD | Cryo-EM structure of a late human pre-40S ribosomal subunit - state F1 | electron microscopy | z | — | — |
| 6ZXE | Cryo-EM structure of a late human pre-40S ribosomal subunit - State F2 | electron microscopy | z | — | 1 (best 0.81) |
| 6ZXE | Cryo-EM structure of a late human pre-40S ribosomal subunit - state F2 | electron microscopy | z | — | — |
| 6ZXF | Cryo-EM structure of a late human pre-40S ribosomal subunit - State G | electron microscopy | z | MG, ATP | 3 (best 0.88) |
| 6ZXF | Cryo-EM structure of a late human pre-40S ribosomal subunit - state G | electron microscopy | z | MG, ATP | — |
| 6ZXG | Cryo-EM structure of a late human pre-40S ribosomal subunit - State H1 | electron microscopy | z | MG, ATP | 5 (best 0.89) |
| 6ZXG | Cryo-EM structure of a late human pre-40S ribosomal subunit - state H1 | electron microscopy | z | MG, ATP | — |
| 6ZXH | Cryo-EM structure of a late human pre-40S ribosomal subunit - State H2 | electron microscopy | z | MG, ATP | 4 (best 0.87) |
| 6ZXH | Cryo-EM structure of a late human pre-40S ribosomal subunit - state H2 | electron microscopy | z | MG, ATP | — |
| Q9BRS2 | AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase RIO1 (Q9BRS2) | predicted | A | — | 7 (best 0.72) |
Ligands
Experiment against prediction
- 4OTP chain A against the predicted model Q9BRS2: TM-score 0.97, RMSD 1.05 Å
- 4OTP chain A against the predicted model Q9BRS2: TM-score 0.97, RMSD 1.05 Å
- 6ZV6 chain h against the predicted model Q9BRS2: TM-score 0.97, RMSD 0.98 Å
- 6ZV6 chain h against the predicted model Q9BRS2: TM-score 0.97, RMSD 0.98 Å
- 6ZXE chain z against the predicted model Q9BRS2: TM-score 0.86, RMSD 1.17 Å
- 6ZXE chain z against the predicted model Q9BRS2: TM-score 0.86, RMSD 1.17 Å
- 6ZXD chain z against the predicted model Q9BRS2: TM-score 0.85, RMSD 1.76 Å
- 6ZXD chain z against the predicted model Q9BRS2: TM-score 0.85, RMSD 1.76 Å
- 6ZXF chain z against the predicted model Q9BRS2: TM-score 0.82, RMSD 2.00 Å
- 6ZXF chain z against the predicted model Q9BRS2: TM-score 0.82, RMSD 2.00 Å
Elsewhere
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