UniProt P62701
40S ribosomal protein S4, X isoform (P62701)
40S ribosomal protein S4, X isoform (UniProt P62701): 121 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 203 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P62701
- Protein
- 40S ribosomal protein S4, X isoform
- Experimental structures
- 121
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 203 · 84 records with a druggable one
Structures
122 records of P62701 in the MolNFT archive: 121 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4UG0 | Structure of the human 80S ribosome | electron microscopy | SE | — | — |
| 4V6X | Structure of the human 80S ribosome | electron microscopy | AE | — | — |
| 5A2Q | Structure of the HCV IRES bound to the human ribosome | electron microscopy | E | MG | 2 (best 0.84) |
| 5A2Q | Structure of the HCV ires bound to the human ribosome | electron microscopy | E | — | — |
| 5LKS | Structure-function insights reveal the human ribosome as a cancer target for antibiotics | electron microscopy | SE | — | — |
| 5OA3 | Human 40S-EIF2D-re-initiation complex | electron microscopy | E | — | — |
| 5VYC | Crystal structure of the human 40S ribosomal subunit in complex with DENR-MCT-1. | x-ray diffraction | E1, E2, E3, E4, E5, E6 | — | 5 (best 0.88) |
| 6FEC | Human cap-dependent 48S pre-initiation complex | electron microscopy | I | — | 1 (best 0.84) |
| 6G18 | Cryo-EM structure of a late human pre-40S ribosomal subunit - State C | electron microscopy | E | — | 3 (best 0.88) |
| 6G18 | Cryo-EM structure of a late human pre-40S ribosomal subunit - state C | electron microscopy | E | — | — |
| 6G4S | Cryo-EM structure of a late human pre-40S ribosomal subunit - State B | electron microscopy | E | — | — |
| 6G4S | Cryo-EM structure of a late human pre-40S ribosomal subunit - state B | electron microscopy | E | — | — |
| 6G4W | Cryo-EM structure of a late human pre-40S ribosomal subunit - State A | electron microscopy | E | — | 1 (best 0.76) |
| 6G4W | Cryo-EM structure of a late human pre-40S ribosomal subunit - state a | electron microscopy | E | — | — |
| 6G51 | Cryo-EM structure of a late human pre-40S ribosomal subunit - State D | electron microscopy | E | — | 1 (best 0.80) |
| 6G51 | Cryo-EM structure of a late human pre-40S ribosomal subunit - state D | electron microscopy | E | — | — |
| 6G53 | Cryo-EM structure of a late human pre-40S ribosomal subunit - State E | electron microscopy | E | — | 2 (best 0.82) |
| 6G53 | Cryo-EM structure of a late human pre-40S ribosomal subunit - state E | electron microscopy | E | — | — |
| 6G5H | Cryo-EM structure of a late human pre-40S ribosomal subunit - Mature | electron microscopy | E | — | 4 (best 0.88) |
| 6G5H | Cryo-EM structure of a late human pre-40S ribosomal subunit - mature | electron microscopy | E | — | — |
| 6G5I | Cryo-EM structure of a late human pre-40S ribosomal subunit - State R | electron microscopy | E | — | 5 (best 0.88) |
| 6G5I | Cryo-EM structure of a late human pre-40S ribosomal subunit - state R | electron microscopy | E | — | — |
| 6IP5 | Cryo-EM structure of the CMV-stalled human 80S ribosome (Structure ii) | electron microscopy | 2q | — | — |
| 6IP8 | Cryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv) | electron microscopy | 2q | — | — |
| 6OLE | Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAs | electron microscopy | SE | — | — |
| 6OLF | Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAs | electron microscopy | SE | — | 1 (best 0.88) |
| 6OLI | Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule… | electron microscopy | SE | — | — |
| 6OM0 | Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE… | electron microscopy | SE | — | 1 (best 0.86) |
| 6OM7 | Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and… | electron microscopy | SE | — | 2 (best 0.88) |
| 6QZP | High-resolution cryo-EM structure of the human 80S ribosome | electron microscopy | SE | MG | 1 (best 0.88) |
| 6XA1 | Structure of a drug-like compound stalled human translation termination complex | electron microscopy | SE | — | 2 (best 0.89) |
| 6Y0G | Structure of human ribosome in classical-PRE state | electron microscopy | SE | MG | 1 (best 0.88) |
| 6Y2L | Structure of human ribosome in POST state | electron microscopy | SE | MG | 1 (best 0.88) |
| 6Y57 | Structure of human ribosome in hybrid-PRE state | electron microscopy | SE | MG | 1 (best 0.86) |
| 6YBW | Structure of a human 48S translational initiation complex - 40S body | electron microscopy | C | — | 5 (best 0.86) |
| 6YBW | Structure of a human 48S translational initiation complex - 40S body | electron microscopy | C | — | — |
| 6Z6L | Cryo-EM structure of human CCDC124 bound to 80S ribosomes | electron microscopy | SE | — | 1 (best 0.86) |
| 6Z6M | Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1 | electron microscopy | SE | — | 2 (best 0.87) |
| 6ZLW | SARS-CoV-2 Nsp1 bound to the human 40S ribosomal subunit | electron microscopy | E | — | 2 (best 0.88) |
| 6ZLW | SARS-cov-2 NSP1 bound to the human 40S ribosomal subunit | electron microscopy | E | — | — |
| 6ZM7 | SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complex | electron microscopy | SE | — | 2 (best 0.88) |
| 6ZMO | SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complex | electron microscopy | SE | — | 2 (best 0.88) |
| 6ZMT | SARS-CoV-2 Nsp1 bound to a pre-40S-like ribosome complex | electron microscopy | E | — | 5 (best 0.88) |
| 6ZMT | SARS-cov-2 NSP1 bound to a pre-40S-like ribosome complex | electron microscopy | E | — | — |
| 6ZN5 | SARS-CoV-2 Nsp1 bound to a pre-40S-like ribosome complex - state 2 | electron microscopy | E | — | 3 (best 0.87) |
| 6ZN5 | SARS-cov-2 NSP1 bound to a pre-40S-like ribosome complex - state 2 | electron microscopy | E | — | — |
| 6ZOJ | SARS-CoV-2-Nsp1-40S complex, composite map | electron microscopy | E | MG | — |
| 6ZOJ | SARS-cov-2-NSP1-40S complex, composite MAP | electron microscopy | E | MG | — |
| 6ZOK | SARS-cov-2-NSP1-40S complex, focused on body | electron microscopy | E | MG | — |
| 6ZON | SARS-CoV-2 Nsp1 bound to a human 43S preinitiation ribosome complex - state 1 | electron microscopy | q | — | 3 (best 0.88) |
| 6ZP4 | SARS-CoV-2 Nsp1 bound to a human 43S preinitiation ribosome complex - state 2 | electron microscopy | q | — | 3 (best 0.88) |
| 6ZUO | Human RIO1(kd)-StHA late pre-40S particle, structural state A (pre 18S rRNA cleavage) | electron microscopy | E | — | 3 (best 0.88) |
| 6ZUO | Human RIO1(KD)-stha late pre-40S particle, structural state a (pre 18S rRNA cleavage) | electron microscopy | E | — | — |
| 6ZV6 | Human RIO1(kd)-StHA late pre-40S particle, structural state B (post 18S rRNA cleavage) | electron microscopy | E | — | 3 (best 0.85) |
| 6ZV6 | Human RIO1(KD)-stha late pre-40S particle, structural state B (post 18S rRNA cleavage) | electron microscopy | E | — | — |
| 6ZVH | EDF1-ribosome complex | electron microscopy | E | — | — |
| 6ZVJ | Structure of a human ABCE1-bound 43S pre-initiation complex - State II | electron microscopy | q | — | 4 (best 0.88) |
| 6ZXD | Cryo-EM structure of a late human pre-40S ribosomal subunit - state F1 | electron microscopy | E | — | — |
| 6ZXE | Cryo-EM structure of a late human pre-40S ribosomal subunit - state F2 | electron microscopy | E | — | — |
| 6ZXF | Cryo-EM structure of a late human pre-40S ribosomal subunit - State G | electron microscopy | E | — | 3 (best 0.89) |
62 records more on the page itself.
Ligands
Experiment against prediction
- 9BLN chain C against the predicted model P62701: TM-score 1.00, RMSD 0.32 Å
- 8GLP chain SE against the predicted model P62701: TM-score 1.00, RMSD 0.33 Å
- 8K2C chain SE against the predicted model P62701: TM-score 1.00, RMSD 0.34 Å
- 6YBW chain C against the predicted model P62701: TM-score 1.00, RMSD 0.34 Å
- 6YBW chain C against the predicted model P62701: TM-score 1.00, RMSD 0.34 Å
- 8G5Y chain SE against the predicted model P62701: TM-score 1.00, RMSD 0.35 Å
- 6ZP4 chain q against the predicted model P62701: TM-score 1.00, RMSD 0.35 Å
- 8YOO chain SE against the predicted model P62701: TM-score 1.00, RMSD 0.36 Å
- 6ZON chain q against the predicted model P62701: TM-score 1.00, RMSD 0.36 Å
- 7WTS chain E against the predicted model P62701: TM-score 1.00, RMSD 0.36 Å
Elsewhere
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