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MolNFT v1 · #129091 · protein + RNA

Human 40S-EIF2D-re-initiation complex

5OA3: “Human 40S-EIF2D-re-initiation complex”. Electron microscopy, 1 ligand (ZN). MolNFT v1 #129091 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
5OA3
Type
protein + RNA
Length
7,270 residues
Chains
38
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P41214, P08865, P61247, P15880, P23396, P62701, P46782, P62753, P62081, P62241, P46781, P46783, P62280, P25398, P62277, P62263, P62841, P62249, P08708, P62269, P39019, P60866, P63220, P62244, P62266, P62847, P62851, P62854, P42677, P62857, P62273, P62861, Q5RKT7, P63244
Ligands
ZN

Structure

electron microscopy · 38 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
0—protein479—P41214
1—rna75——
2—rna1661——
3—rna186——
A—protein216—P08865
B—protein213—P61247
C—protein218—P15880
D—protein225—P23396
E—protein262—P62701
F—protein189—P46782
G—protein230—P62753
H—protein186—P62081
I—protein205—P62241
J—protein180—P46781
K—protein95—P46783
L—protein151—P62280
M—protein123—P25398
N—protein149—P62277
O—protein135—P62263
P—protein120—P62841
Q—protein139—P62249
R—protein132—P08708
S—protein143—P62269
T—protein144—P39019
U—protein101—P60866
V—protein82—P63220
W—protein129—P62244
X—protein141—P62266
Y—protein124—P62847
Z—protein72—P62851
a—protein101—P62854
b—protein82—P42677
c—protein61—P62857
d—protein55—P62273
e—protein56—P62861
f—protein72—Q5RKT7
g—protein314—P63244
h—protein24——

Ligands and binding sites

  • ZN · Zinc ion · metal · 3 copies · chains a, d, f

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • P62701 · AlphaFold monomer V2.0 prediction for 40S ribosomal protein S4, X isoform (P62701) · a predicted model of the same protein · chain E against A, TM-score 0.99
  • P15880 · AlphaFold monomer V2.0 prediction for 40S ribosomal protein S2 (P15880) · a predicted model of the same protein · chain C against A, TM-score 0.99
  • P62244 · AlphaFold monomer V2.0 prediction for 40S ribosomal protein S15A (P62244) · a predicted model of the same protein · chain W against A, TM-score 0.98
  • P62263 · AlphaFold monomer V2.0 prediction for 40S ribosomal protein S14 (P62263) · a predicted model of the same protein · chain O against A, TM-score 0.98
  • P63244 · AlphaFold monomer V2.0 prediction for receptor of activated protein C kinase 1 (P63244) · a predicted model of the same protein · chain g against A, TM-score 0.98
  • P62249 · AlphaFold monomer V2.0 prediction for 40S ribosomal protein S16 (P62249) · a predicted model of the same protein · chain Q against A, TM-score 0.98
  • P63220 · AlphaFold monomer V2.0 prediction for 40S ribosomal protein S21 (P63220) · a predicted model of the same protein · chain V against A, TM-score 0.97
  • P46781 · AlphaFold monomer V2.0 prediction for 40S ribosomal protein S9 (P46781) · a predicted model of the same protein · chain J against A, TM-score 0.97
  • P62241 · AlphaFold monomer V2.0 prediction for 40S ribosomal protein S8 (P62241) · a predicted model of the same protein · chain I against A, TM-score 0.97
  • P62854 · AlphaFold monomer V2.0 prediction for 40S ribosomal protein S26 (P62854) · a predicted model of the same protein · chain a against A, TM-score 0.96
  • P46783 · AlphaFold monomer V2.0 prediction for 40S ribosomal protein S10 (P46783) · a predicted model of the same protein · chain K against A, TM-score 0.96
  • P23396 · AlphaFold monomer V2.0 prediction for 40S ribosomal protein S3 (P23396) · a predicted model of the same protein · chain D against A, TM-score 0.96

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