AlphaFold monomer V2.0 prediction for 40S ribosomal protein S8 (P62241)

Structure

1 distinct chain · 33% helix, 25% strand (DSSP).

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Compared structures

• 8G60 · mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state) · an experimental structure of the same protein · chain A against SI, TM-score 0.96
• 6ZVH · EDF1-ribosome complex · an experimental structure of the same protein · chain A against I, TM-score 0.96
• 8G5Y · mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state) · an experimental structure of the same protein · chain A against SI, TM-score 0.96
• 7XNX · High resolution cry-EM structure of the human 80S ribosome from SNORD127+/+ Kasumi-1 cells · an experimental structure of the same protein · chain A against SI, TM-score 0.96
• 5A2Q · Structure of the HCV ires bound to the human ribosome · an experimental structure of the same protein · chain A against I, TM-score 0.95
• 8G61 · mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state) · an experimental structure of the same protein · chain A against SI, TM-score 0.95
• 8K2C · Cryo-EM structure of the human 80S ribosome with Tigecycline · an experimental structure of the same protein · chain A against SI, TM-score 0.95
• 7XNY · High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cells · an experimental structure of the same protein · chain A against SI, TM-score 0.95
• 5OA3 · Human 40S-EIF2D-re-initiation complex · an experimental structure of the same protein · chain A against I, TM-score 0.95
• 7QVP · Human collided disome (di-ribosome) stalled on XBP1 mRNA · an experimental structure of the same protein · chain A against SI, TM-score 0.95
• 6G53 · Cryo-EM structure of a late human pre-40S ribosomal subunit - state E · an experimental structure of the same protein · chain A against I, TM-score 0.95
• 6G51 · Cryo-EM structure of a late human pre-40S ribosomal subunit - state D · an experimental structure of the same protein · chain A against I, TM-score 0.95

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P62241
• Elsewhere: UniProt P62241 · AlphaFold DB P62241