MolNFT v1 · #409516 · protein
AlphaFold monomer V2.0 prediction for 40S ribosomal protein S8 (P62241)
P62241: “AlphaFold monomer V2.0 prediction for 40S ribosomal protein S8 (P62241)”. 2 pockets (best druggability 0.30). MolNFT v1 #409516 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P62241
- Type
- protein
- Length
- 208 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xFb1Fd01bBa777F5321d3CeBE17CEDAC28290Fb4D
- Molecule
- 40S ribosomal protein S8
- UniProt
- P62241
- Pockets
- 2 · best druggability 0.30
Structure
1 distinct chain · 33% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 40S ribosomal protein S8 | protein | 208 | 33% helix, 25% strand | P62241 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 60 | 0.30 | 0.75 | 16 | empty |
| 2 | 53 | 0.28 | 0.75 | 16 | empty |
Compared structures
- 9C3H · Structure of the CNOT3-bound human 80S ribosome with tRNA-ARG in the P-site. · an experimental structure of the same protein · chain A against SI, TM-score 0.96
- 8G60 · mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state) · an experimental structure of the same protein · chain A against SI, TM-score 0.96
- 8YOO · Cryo-EM structure of the human 80S ribosome with 100 um Tigecycline · an experimental structure of the same protein · chain A against SI, TM-score 0.96
- 8G5Z · mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state) · an experimental structure of the same protein · chain A against SI, TM-score 0.96
- 8G6J · mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2) · an experimental structure of the same protein · chain A against SI, TM-score 0.96
- 8GLP · mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus… · an experimental structure of the same protein · chain A against SI, TM-score 0.96
- 8QOI · Structure of the human 80S ribosome at 1.9 A resolution - the molecular role of chemical… · an experimental structure of the same protein · chain A against SI, TM-score 0.96
- 6ZVH · EDF1-ribosome complex · an experimental structure of the same protein · chain A against I, TM-score 0.96
- 6ZVH · EDF1-ribosome complex · an experimental structure of the same protein · chain A against I, TM-score 0.96
- 8G5Y · mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state) · an experimental structure of the same protein · chain A against SI, TM-score 0.96
- 7XNX · High resolution cry-EM structure of the human 80S ribosome from SNORD127+/+ Kasumi-1 cells · an experimental structure of the same protein · chain A against SI, TM-score 0.96
- 6QZP · High-resolution cryo-EM structure of the human 80S ribosome · an experimental structure of the same protein · chain A against SI, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P62241
- Elsewhere: UniProt P62241 · AlphaFold DB P62241
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