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MolNFT v1 · #409516 · protein

AlphaFold monomer V2.0 prediction for 40S ribosomal protein S8 (P62241)

P62241: “AlphaFold monomer V2.0 prediction for 40S ribosomal protein S8 (P62241)”. 2 pockets (best druggability 0.30). MolNFT v1 #409516 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
P62241
Type
protein
Length
208 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xFb1Fd01bBa777F5321d3CeBE17CEDAC28290Fb4D
Molecule
40S ribosomal protein S8
UniProt
P62241
Pockets
2 · best druggability 0.30

Structure

1 distinct chain · 33% helix, 25% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A40S ribosomal protein S8protein20833% helix, 25% strandP62241

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1600.300.7516empty
2530.280.7516empty

Compared structures

  • 9C3H · Structure of the CNOT3-bound human 80S ribosome with tRNA-ARG in the P-site. · an experimental structure of the same protein · chain A against SI, TM-score 0.96
  • 8G60 · mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state) · an experimental structure of the same protein · chain A against SI, TM-score 0.96
  • 8YOO · Cryo-EM structure of the human 80S ribosome with 100 um Tigecycline · an experimental structure of the same protein · chain A against SI, TM-score 0.96
  • 8G5Z · mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state) · an experimental structure of the same protein · chain A against SI, TM-score 0.96
  • 8G6J · mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2) · an experimental structure of the same protein · chain A against SI, TM-score 0.96
  • 8GLP · mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus… · an experimental structure of the same protein · chain A against SI, TM-score 0.96
  • 8QOI · Structure of the human 80S ribosome at 1.9 A resolution - the molecular role of chemical… · an experimental structure of the same protein · chain A against SI, TM-score 0.96
  • 6ZVH · EDF1-ribosome complex · an experimental structure of the same protein · chain A against I, TM-score 0.96
  • 6ZVH · EDF1-ribosome complex · an experimental structure of the same protein · chain A against I, TM-score 0.96
  • 8G5Y · mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state) · an experimental structure of the same protein · chain A against SI, TM-score 0.96
  • 7XNX · High resolution cry-EM structure of the human 80S ribosome from SNORD127+/+ Kasumi-1 cells · an experimental structure of the same protein · chain A against SI, TM-score 0.96
  • 6QZP · High-resolution cryo-EM structure of the human 80S ribosome · an experimental structure of the same protein · chain A against SI, TM-score 0.96

Analyse

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