UniProt P15880
40S ribosomal protein S2 (P15880)
40S ribosomal protein S2 (UniProt P15880): 74 experimental structures on GenesisL1, 2 ligands bound, 38 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P15880
- Protein
- 40S ribosomal protein S2
- Experimental structures
- 74
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 38 · 31 records with a druggable one
Structures
74 records of P15880 in the MolNFT archive: 74 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4UG0 | Structure of the human 80S ribosome | electron microscopy | SC | — | — |
| 4V6X | Structure of the human 80S ribosome | electron microscopy | AC | — | — |
| 5A2Q | Structure of the HCV IRES bound to the human ribosome | electron microscopy | C | MG | 2 (best 0.85) |
| 5A2Q | Structure of the HCV ires bound to the human ribosome | electron microscopy | C | — | — |
| 5FLX | Mammalian 40S HCV-IRES complex | electron microscopy | C | MG | 3 (best 0.87) |
| 5FLX | Mammalian 40S HCV-ires complex | electron microscopy | C | — | — |
| 5LKS | Structure-function insights reveal the human ribosome as a cancer target for antibiotics | electron microscopy | SC | — | — |
| 5OA3 | Human 40S-EIF2D-re-initiation complex | electron microscopy | C | — | — |
| 6G18 | Cryo-EM structure of a late human pre-40S ribosomal subunit - state C | electron microscopy | C | — | — |
| 6G4S | Cryo-EM structure of a late human pre-40S ribosomal subunit - State B | electron microscopy | C | — | 1 (best 0.81) |
| 6G4S | Cryo-EM structure of a late human pre-40S ribosomal subunit - state B | electron microscopy | C | — | — |
| 6G51 | Cryo-EM structure of a late human pre-40S ribosomal subunit - state D | electron microscopy | C | — | — |
| 6G53 | Cryo-EM structure of a late human pre-40S ribosomal subunit - state E | electron microscopy | C | — | — |
| 6G5H | Cryo-EM structure of a late human pre-40S ribosomal subunit - mature | electron microscopy | C | — | — |
| 6G5I | Cryo-EM structure of a late human pre-40S ribosomal subunit - state R | electron microscopy | C | — | — |
| 6IP8 | Cryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv) | electron microscopy | 3G | — | — |
| 6OLE | Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAs | electron microscopy | SC | — | — |
| 6OLF | Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAs | electron microscopy | SC | — | 1 (best 0.87) |
| 6OLI | Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule… | electron microscopy | SC | — | — |
| 6OM7 | Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and… | electron microscopy | SC | — | 1 (best 0.86) |
| 6XA1 | Structure of a drug-like compound stalled human translation termination complex | electron microscopy | SC | — | 1 (best 0.86) |
| 6YBD | Structure of a human 48S translational initiation complex - EIF3 | electron microscopy | L | — | — |
| 6YBW | Structure of a human 48S translational initiation complex - 40S body | electron microscopy | L | — | 1 (best 0.86) |
| 6YBW | Structure of a human 48S translational initiation complex - 40S body | electron microscopy | L | — | — |
| 6Z6L | Cryo-EM structure of human CCDC124 bound to 80S ribosomes | electron microscopy | SC | — | 1 (best 0.86) |
| 6ZLW | SARS-cov-2 NSP1 bound to the human 40S ribosomal subunit | electron microscopy | D | — | — |
| 6ZMO | SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complex | electron microscopy | SC | — | 1 (best 0.88) |
| 6ZMT | SARS-CoV-2 Nsp1 bound to a pre-40S-like ribosome complex | electron microscopy | D | — | 1 (best 0.83) |
| 6ZMT | SARS-cov-2 NSP1 bound to a pre-40S-like ribosome complex | electron microscopy | D | — | — |
| 6ZN5 | SARS-cov-2 NSP1 bound to a pre-40S-like ribosome complex - state 2 | electron microscopy | D | — | — |
| 6ZOJ | SARS-CoV-2-Nsp1-40S complex, composite map | electron microscopy | C | — | — |
| 6ZOJ | SARS-cov-2-NSP1-40S complex, composite MAP | electron microscopy | C | — | — |
| 6ZOK | SARS-cov-2-NSP1-40S complex, focused on body | electron microscopy | C | — | — |
| 6ZUO | Human RIO1(KD)-stha late pre-40S particle, structural state a (pre 18S rRNA cleavage) | electron microscopy | C | — | — |
| 6ZV6 | Human RIO1(kd)-StHA late pre-40S particle, structural state B (post 18S rRNA cleavage) | electron microscopy | C | — | 2 (best 0.86) |
| 6ZV6 | Human RIO1(KD)-stha late pre-40S particle, structural state B (post 18S rRNA cleavage) | electron microscopy | C | — | — |
| 6ZVH | EDF1-ribosome complex | electron microscopy | C | — | — |
| 6ZXD | Cryo-EM structure of a late human pre-40S ribosomal subunit - state F1 | electron microscopy | C | — | — |
| 6ZXE | Cryo-EM structure of a late human pre-40S ribosomal subunit - state F2 | electron microscopy | C | — | — |
| 6ZXF | Cryo-EM structure of a late human pre-40S ribosomal subunit - state G | electron microscopy | C | — | — |
| 6ZXG | Cryo-EM structure of a late human pre-40S ribosomal subunit - state H1 | electron microscopy | C | — | — |
| 6ZXH | Cryo-EM structure of a late human pre-40S ribosomal subunit - state H2 | electron microscopy | C | — | — |
| 7A09 | Structure of a human ABCE1-bound 43S pre-initiation complex - State III | electron microscopy | d | — | — |
| 7K5I | SARS-cov-2 NSP1 in complex with human 40S ribosome | electron microscopy | C | — | — |
| 7QP6 | Structure of the human 48S initiation complex in open state (h48S AUG open) | electron microscopy | L | — | 1 (best 0.89) |
| 7QP7 | Structure of the human 48S initiation complex in closed state (h48S AUG closed) | electron microscopy | L | — | 2 (best 0.87) |
| 7QVP | Human collided disome (di-ribosome) stalled on XBP1 mRNA | electron microscopy | RC, SC | — | — |
| 7TQL | Cryoem structure of the human 40S small ribosomal subunit in complex with translation initiation… | electron microscopy | D | — | — |
| 7WTW | Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A3 | electron microscopy | C | — | 2 (best 0.87) |
| 7WTX | Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-B1 | electron microscopy | C | — | 1 (best 0.85) |
| 7XNX | High resolution cry-EM structure of the human 80S ribosome from SNORD127+/+ Kasumi-1 cells | electron microscopy | SC | MG | 1 (best 0.87) |
| 7XNY | High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cells | electron microscopy | SC | MG | 1 (best 0.87) |
| 8G5Y | mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state) | electron microscopy | SC | MG | 2 (best 0.88) |
| 8G5Z | mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state) | electron microscopy | SC | — | 1 (best 0.88) |
| 8G60 | mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state) | electron microscopy | SC | MG | — |
| 8G61 | mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state) | electron microscopy | SC | MG | 1 (best 0.88) |
| 8GLP | mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU… | electron microscopy | SC | MG | — |
| 8JDJ | Structure of the Human cytoplasmic Ribosome with human tRNA Asp(Q34) and mRNA(GAU) | electron microscopy | z | — | — |
| 8JDK | Structure of the Human cytoplasmic Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU) | electron microscopy | z | — | — |
| 8K2C | Cryo-EM structure of the human 80S ribosome with Tigecycline | electron microscopy | SC | — | 1 (best 0.86) |
14 records more on the page itself.
Ligands
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