UniProt P62857
40S ribosomal protein S28 (P62857)
40S ribosomal protein S28 (UniProt P62857): 60 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P62857
- Protein
- 40S ribosomal protein S28
- Experimental structures
- 60
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 4 · 3 records with a druggable one
Structures
61 records of P62857 in the MolNFT archive: 60 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4UG0 | Structure of the human 80S ribosome | electron microscopy | Sc | — | — |
| 4V6X | Structure of the human 80S ribosome | electron microscopy | Ac | — | — |
| 5A2Q | Structure of the HCV IRES bound to the human ribosome | electron microscopy | c | — | — |
| 5A2Q | Structure of the HCV ires bound to the human ribosome | electron microscopy | c | — | — |
| 5FLX | Mammalian 40S HCV-IRES complex | electron microscopy | c | — | — |
| 5FLX | Mammalian 40S HCV-ires complex | electron microscopy | c | — | — |
| 5LKS | Structure-function insights reveal the human ribosome as a cancer target for antibiotics | electron microscopy | Sc | — | — |
| 5OA3 | Human 40S-EIF2D-re-initiation complex | electron microscopy | c | — | — |
| 6G18 | Cryo-EM structure of a late human pre-40S ribosomal subunit - state C | electron microscopy | c | — | — |
| 6G4S | Cryo-EM structure of a late human pre-40S ribosomal subunit - State B | electron microscopy | c | — | 1 (best 0.79) |
| 6G4S | Cryo-EM structure of a late human pre-40S ribosomal subunit - state B | electron microscopy | c | — | — |
| 6G4W | Cryo-EM structure of a late human pre-40S ribosomal subunit - state a | electron microscopy | c | — | — |
| 6G51 | Cryo-EM structure of a late human pre-40S ribosomal subunit - state D | electron microscopy | c | — | — |
| 6G53 | Cryo-EM structure of a late human pre-40S ribosomal subunit - state E | electron microscopy | c | — | — |
| 6G5H | Cryo-EM structure of a late human pre-40S ribosomal subunit - mature | electron microscopy | c | — | — |
| 6G5I | Cryo-EM structure of a late human pre-40S ribosomal subunit - state R | electron microscopy | c | — | — |
| 6IP8 | Cryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv) | electron microscopy | 3D | — | — |
| 6OLE | Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAs | electron microscopy | Sc | — | — |
| 6OLI | Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule… | electron microscopy | Sc | — | — |
| 6YBS | Structure of a human 48S translational initiation complex - head | electron microscopy | n | — | — |
| 6ZLW | SARS-cov-2 NSP1 bound to the human 40S ribosomal subunit | electron microscopy | d | — | — |
| 6ZMT | SARS-cov-2 NSP1 bound to a pre-40S-like ribosome complex | electron microscopy | d | — | — |
| 6ZN5 | SARS-cov-2 NSP1 bound to a pre-40S-like ribosome complex - state 2 | electron microscopy | d | — | — |
| 6ZOJ | SARS-CoV-2-Nsp1-40S complex, composite map | electron microscopy | c | — | — |
| 6ZOJ | SARS-cov-2-NSP1-40S complex, composite MAP | electron microscopy | c | — | — |
| 6ZOL | SARS-cov-2-NSP1-40S complex, focused on head | electron microscopy | c | — | — |
| 6ZUO | Human RIO1(KD)-stha late pre-40S particle, structural state a (pre 18S rRNA cleavage) | electron microscopy | c | — | — |
| 6ZV6 | Human RIO1(kd)-StHA late pre-40S particle, structural state B (post 18S rRNA cleavage) | electron microscopy | c | — | — |
| 6ZV6 | Human RIO1(KD)-stha late pre-40S particle, structural state B (post 18S rRNA cleavage) | electron microscopy | c | — | — |
| 6ZVH | EDF1-ribosome complex | electron microscopy | c | — | — |
| 6ZXD | Cryo-EM structure of a late human pre-40S ribosomal subunit - state F1 | electron microscopy | c | — | — |
| 6ZXE | Cryo-EM structure of a late human pre-40S ribosomal subunit - state F2 | electron microscopy | c | — | — |
| 6ZXF | Cryo-EM structure of a late human pre-40S ribosomal subunit - state G | electron microscopy | c | — | — |
| 6ZXG | Cryo-EM structure of a late human pre-40S ribosomal subunit - state H1 | electron microscopy | c | — | — |
| 6ZXH | Cryo-EM structure of a late human pre-40S ribosomal subunit - state H2 | electron microscopy | c | — | — |
| 7A09 | Structure of a human ABCE1-bound 43S pre-initiation complex - State III | electron microscopy | S | — | — |
| 7K5I | SARS-cov-2 NSP1 in complex with human 40S ribosome | electron microscopy | c | — | — |
| 7MQA | Cryo-EM structure of the human SSU processome, state post-A1 | electron microscopy | LG | — | — |
| 7QP6 | Structure of the human 48S initiation complex in open state (h48S AUG open) | electron microscopy | n | — | 2 (best 0.86) |
| 7QP7 | Structure of the human 48S initiation complex in closed state (h48S AUG closed) | electron microscopy | n | — | — |
| 7WTT | Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A1 (with CK1) | electron microscopy | c | — | 1 (best 0.83) |
| 7WTW | Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A3 | electron microscopy | c | — | — |
| 7WTX | Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-B1 | electron microscopy | c | — | — |
| 7XNX | High resolution cry-EM structure of the human 80S ribosome from SNORD127+/+ Kasumi-1 cells | electron microscopy | Sc | — | — |
| 7XNY | High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cells | electron microscopy | Sc | — | — |
| 8G5Y | mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state) | electron microscopy | Sc | — | — |
| 8G60 | mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state) | electron microscopy | Sc | — | — |
| 8G61 | mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state) | electron microscopy | Sc | — | — |
| 8GLP | mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU… | electron microscopy | Sc | — | — |
| 8JDJ | Structure of the Human cytoplasmic Ribosome with human tRNA Asp(Q34) and mRNA(GAU) | electron microscopy | AO | — | — |
| 8JDK | Structure of the Human cytoplasmic Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU) | electron microscopy | AO | — | — |
| 8K2C | Cryo-EM structure of the human 80S ribosome with Tigecycline | electron microscopy | Sc | — | — |
| 8PPK | Bat-Hp-CoV Nsp1 and eIF1 bound to the human 40S small ribosomal subunit | electron microscopy | c | — | — |
| 8PPL | MERS-CoV Nsp1 bound to the human 43S pre-initiation complex | electron microscopy | Ac | — | — |
| 8UKB | In situ HHT and CHX treated human hibernating state without E-tRNA 80S ribosome | electron microscopy | Sc | — | — |
| 8XSX | Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2 | electron microscopy | Sc | — | — |
| 8XXM | Cryo-EM structure of the human 40S ribosome with PDCD4 and eIF3G | electron microscopy | Sc | — | — |
| 8YOP | Cryo-EM structure of the human 80S ribosome with 4 um Tigecycline | electron microscopy | Sc | — | — |
| 9G8M | human 80S ribosome bound by a SKI2-exosome complex | electron microscopy | Sc | MG | — |
| 9G8O | human 40S ribosome bound by a SKI238-exosome complex | electron microscopy | Sc | — | — |
1 record more on the page itself.
Ligands
- MG · Magnesium ion · in 1 record
Experiment against prediction
- 6ZOL chain c against the predicted model P62857: TM-score 0.97, RMSD 0.46 Å
- 6ZOJ chain c against the predicted model P62857: TM-score 0.97, RMSD 0.46 Å
- 6ZOJ chain c against the predicted model P62857: TM-score 0.97, RMSD 0.46 Å
- 9G8O chain Sc against the predicted model P62857: TM-score 0.96, RMSD 0.57 Å
- 8YOP chain Sc against the predicted model P62857: TM-score 0.94, RMSD 0.82 Å
- 8K2C chain Sc against the predicted model P62857: TM-score 0.94, RMSD 0.84 Å
- 7K5I chain c against the predicted model P62857: TM-score 0.93, RMSD 1.36 Å
- 8G60 chain Sc against the predicted model P62857: TM-score 0.93, RMSD 0.98 Å
- 8JDJ chain AO against the predicted model P62857: TM-score 0.93, RMSD 0.74 Å
- 8G5Y chain Sc against the predicted model P62857: TM-score 0.93, RMSD 1.23 Å
Elsewhere
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