Research workbench
Human 40S-EIF2D-re-initiation complex
Analyse Human 40S-EIF2D-re-initiation complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5OA3
- Type
- protein + RNA
- Length
- 7,270 residues
- Chains
- 38
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P41214, P08865, P61247, P15880, P23396, P62701, P46782, P62753, P62081, P62241, P46781, P46783, P62280, P25398, P62277, P62263, P62841, P62249, P08708, P62269, P39019, P60866, P63220, P62244, P62266, P62847, P62851, P62854, P42677, P62857, P62273, P62861, Q5RKT7, P63244
- Ligands
- ZN
Structure
electron microscopy · 38 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| 0 | — | protein | 479 | — | P41214 |
| 1 | — | rna | 75 | — | — |
| 2 | — | rna | 1661 | — | — |
| 3 | — | rna | 186 | — | — |
| A | — | protein | 216 | — | P08865 |
| B | — | protein | 213 | — | P61247 |
| C | — | protein | 218 | — | P15880 |
| D | — | protein | 225 | — | P23396 |
| E | — | protein | 262 | — | P62701 |
| F | — | protein | 189 | — | P46782 |
| G | — | protein | 230 | — | P62753 |
| H | — | protein | 186 | — | P62081 |
| I | — | protein | 205 | — | P62241 |
| J | — | protein | 180 | — | P46781 |
| K | — | protein | 95 | — | P46783 |
| L | — | protein | 151 | — | P62280 |
| M | — | protein | 123 | — | P25398 |
| N | — | protein | 149 | — | P62277 |
| O | — | protein | 135 | — | P62263 |
| P | — | protein | 120 | — | P62841 |
| Q | — | protein | 139 | — | P62249 |
| R | — | protein | 132 | — | P08708 |
| S | — | protein | 143 | — | P62269 |
| T | — | protein | 144 | — | P39019 |
| U | — | protein | 101 | — | P60866 |
| V | — | protein | 82 | — | P63220 |
| W | — | protein | 129 | — | P62244 |
| X | — | protein | 141 | — | P62266 |
| Y | — | protein | 124 | — | P62847 |
| Z | — | protein | 72 | — | P62851 |
| a | — | protein | 101 | — | P62854 |
| b | — | protein | 82 | — | P42677 |
| c | — | protein | 61 | — | P62857 |
| d | — | protein | 55 | — | P62273 |
| e | — | protein | 56 | — | P62861 |
| f | — | protein | 72 | — | Q5RKT7 |
| g | — | protein | 314 | — | P63244 |
| h | — | protein | 24 | — | — |
Ligands and binding sites
- ZN · Zinc ion · metal · 3 copies · chains a, d, f
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- P62701 · AlphaFold monomer V2.0 prediction for 40S ribosomal protein S4, X isoform (P62701) · a predicted model of the same protein · chain E against A, TM-score 0.99
- P15880 · AlphaFold monomer V2.0 prediction for 40S ribosomal protein S2 (P15880) · a predicted model of the same protein · chain C against A, TM-score 0.99
- P62244 · AlphaFold monomer V2.0 prediction for 40S ribosomal protein S15A (P62244) · a predicted model of the same protein · chain W against A, TM-score 0.98
- P62263 · AlphaFold monomer V2.0 prediction for 40S ribosomal protein S14 (P62263) · a predicted model of the same protein · chain O against A, TM-score 0.98
- P63244 · AlphaFold monomer V2.0 prediction for receptor of activated protein C kinase 1 (P63244) · a predicted model of the same protein · chain g against A, TM-score 0.98
- P62249 · AlphaFold monomer V2.0 prediction for 40S ribosomal protein S16 (P62249) · a predicted model of the same protein · chain Q against A, TM-score 0.98
- P63220 · AlphaFold monomer V2.0 prediction for 40S ribosomal protein S21 (P63220) · a predicted model of the same protein · chain V against A, TM-score 0.97
- P46781 · AlphaFold monomer V2.0 prediction for 40S ribosomal protein S9 (P46781) · a predicted model of the same protein · chain J against A, TM-score 0.97
- P62241 · AlphaFold monomer V2.0 prediction for 40S ribosomal protein S8 (P62241) · a predicted model of the same protein · chain I against A, TM-score 0.97
- P62854 · AlphaFold monomer V2.0 prediction for 40S ribosomal protein S26 (P62854) · a predicted model of the same protein · chain a against A, TM-score 0.96
- P46783 · AlphaFold monomer V2.0 prediction for 40S ribosomal protein S10 (P46783) · a predicted model of the same protein · chain K against A, TM-score 0.96
- P23396 · AlphaFold monomer V2.0 prediction for 40S ribosomal protein S3 (P23396) · a predicted model of the same protein · chain D against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P41214
- Every structure of UniProt P08865
- Every structure of UniProt P61247
- Every structure of UniProt P15880
- Every structure of UniProt P23396
- Every structure of UniProt P62701
- Every structure of UniProt P46782
- Every structure of UniProt P62753
- Every structure of UniProt P62081
- Every structure of UniProt P62241
- Every structure of UniProt P46781
- Every structure of UniProt P46783
- Every structure of UniProt P62280
- Every structure of UniProt P25398
- Every structure of UniProt P62277
- Every structure of UniProt P62263
- Every structure of UniProt P62841
- Every structure of UniProt P62249
- Every structure of UniProt P08708
- Every structure of UniProt P62269
- Every structure of UniProt P39019
- Every structure of UniProt P60866
- Every structure of UniProt P63220
- Every structure of UniProt P62244
- Every structure of UniProt P62266
- Every structure of UniProt P62847
- Every structure of UniProt P62851
- Every structure of UniProt P62854
- Every structure of UniProt P42677
- Every structure of UniProt P62857
- Every structure of UniProt P62273
- Every structure of UniProt P62861
- Every structure of UniProt Q5RKT7
- Every structure of UniProt P63244
- Elsewhere: RCSB PDB 5OA3 · PDBe 5OA3 · UniProt P41214 · UniProt P08865 · UniProt P61247 · UniProt P15880 · UniProt P23396 · UniProt P62701 · UniProt P46782 · UniProt P62753 · UniProt P62081 · UniProt P62241 · UniProt P46781 · UniProt P46783 · UniProt P62280 · UniProt P25398 · UniProt P62277 · UniProt P62263 · UniProt P62841 · UniProt P62249 · UniProt P08708 · UniProt P62269 · UniProt P39019 · UniProt P60866 · UniProt P63220 · UniProt P62244 · UniProt P62266 · UniProt P62847 · UniProt P62851 · UniProt P62854 · UniProt P42677 · UniProt P62857 · UniProt P62273 · UniProt P62861 · UniProt Q5RKT7 · UniProt P63244
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