UniProt Q92973
Transportin-1 (Q92973)
Transportin-1 (UniProt Q92973): 41 experimental structures and 1 predicted model on GenesisL1, 64 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q92973
- Protein
- Transportin-1
- Experimental structures
- 41
- Predicted models
- 1
- Pockets
- 64 · 6 records with a druggable one
Structures
42 records of Q92973 in the MolNFT archive: 41 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1QBK | Structure of the karyopherin BETA2-ran gppnhp nuclear transport complex | x-ray diffraction | B | — | — |
| 1QBK | Structure of the karyopherin BETA2-ran gppnhp nuclear transport complex | x-ray diffraction | B | — | — |
| 2H4M | Karyopherin Beta2/Transportin-M9NLS | x-ray diffraction | A, B | — | — |
| 2H4M | Karyopherin BETA2/TRANSPORTIN-M9NLS | x-ray diffraction | A, B | — | — |
| 2OT8 | Karyopherin Beta2/Transportin-hnRNPM NLS Complex | x-ray diffraction | A, B | — | — |
| 2OT8 | Karyopherin BETA2/TRANSPORTIN-hnrnpm nls complex | x-ray diffraction | A, B | — | — |
| 2QMR | Karyopherin beta2/transportin | x-ray diffraction | A, B, C, D | — | — |
| 2QMR | Karyopherin BETA2/TRANSPORTIN | x-ray diffraction | A, B, C, D | — | — |
| 2Z5J | Free Transportin 1 | x-ray diffraction | A | — | — |
| 2Z5J | Free transportin 1 | x-ray diffraction | A | — | — |
| 2Z5K | Complex of Transportin 1 with TAP NLS | x-ray diffraction | A | — | — |
| 2Z5K | Complex of transportin 1 with tap nls | x-ray diffraction | A | — | — |
| 2Z5M | Complex of Transportin 1 with TAP NLS, crystal form 2 | x-ray diffraction | A | — | — |
| 2Z5M | Complex of transportin 1 with tap nls, crystal form 2 | x-ray diffraction | A | — | — |
| 2Z5N | Complex of Transportin 1 with hnRNP D NLS | x-ray diffraction | A | — | — |
| 2Z5N | Complex of transportin 1 with hnrnp D nls | x-ray diffraction | A | — | — |
| 2Z5O | Complex of Transportin 1 with JKTBP NLS | x-ray diffraction | A | — | — |
| 2Z5O | Complex of transportin 1 with jktbp nls | x-ray diffraction | A | — | — |
| 4FDD | Crystal structure of KAP beta2-PY-NLS | x-ray diffraction | A | — | — |
| 4FDD | Crystal structure of kap BETA2-py-nls | x-ray diffraction | A | — | — |
| 4FQ3 | Crystal structure of transportin/FUS-NLS | x-ray diffraction | A | — | — |
| 4FQ3 | Crystal structure of TRANSPORTIN/FUS-nls | x-ray diffraction | A | — | — |
| 4JLQ | Crystal structure of human Karyopherin-beta2 bound to the PY-NLS of Saccharomyces cerevisiae NAB2 | x-ray diffraction | A | — | — |
| 4JLQ | Crystal structure of human karyopherin-BETA2 bound to the py-nls of saccharomyces cerevisiae NAB2 | x-ray diffraction | A | — | — |
| 4OO6 | Crystal structure of human KAP-beta2 bound to the NLS of HCC1 (Hepato Cellular Carcinoma protein 1) | x-ray diffraction | A | — | — |
| 4OO6 | Crystal structure of human kap-BETA2 bound to the nls of HCC1 (hepato cellular carcinoma protein 1) | x-ray diffraction | A | — | — |
| 5J3V | Crystal structure of human Karyopherin-beta2 bound to the histone H3 tail | x-ray diffraction | A, B | — | 15 (best 0.66) |
| 5J3V | Crystal structure of human karyopherin-BETA2 bound to the histone H3 tail | x-ray diffraction | A, B | — | — |
| 5TQC | Crystal structure of transport factor karyopherin-beta 2 in complex with the PY-NLS of ribosomal… | x-ray diffraction | A | — | 6 (best 0.69) |
| 5TQC | Crystal structure of transport factor karyopherin-beta 2 in complex with the py-nls of ribosomal… | x-ray diffraction | A | — | — |
| 5YVG | Crystal structure of Karyopherin beta2 in complex with FUS(full length) | x-ray diffraction | A, B | — | — |
| 5YVG | Crystal structure of karyopherin BETA2 in complex with FUS(FULL length) | x-ray diffraction | A, B | — | — |
| 5YVH | Crystal structure of Karyopherin beta2 in complex with FUS(371-526) | x-ray diffraction | A | — | 12 (best 0.56) |
| 5YVH | Crystal structure of karyopherin BETA2 in complex with FUS(371-526) | x-ray diffraction | A | — | — |
| 5YVI | Crystal structure of Karyopherin beta2 in complex with FUS(456-526) | x-ray diffraction | A | — | 8 (best 0.48) |
| 5YVI | Crystal structure of karyopherin BETA2 in complex with FUS(456-526) | x-ray diffraction | A | — | — |
| 7CYL | Crystal structure of Karyopherin-beta2 in complex with FUS PY-NLS(P525L) | x-ray diffraction | A | — | 4 (best 0.64) |
| 7CYL | Crystal structure of karyopherin-BETA2 in complex with fus py- NLS(P525L) | x-ray diffraction | A | — | — |
| 7VPW | Crystal structure of Transportin-1 in complex with BAP1 PY-NLS (residues 706-724) | x-ray diffraction | A | — | 5 (best 0.42) |
| 7VPW | Crystal structure of transportin-1 in complex with BAP1 py-nls (residues 706-724) | x-ray diffraction | A | — | — |
| 8SGH | Cryo-EM structure of Karyopherin-beta2 bound to HNRNPH2 PY-NLS | electron microscopy | A | — | 6 (best 0.72) |
| Q92973 | AlphaFold monomer V2.0 prediction for transportin-1 (Q92973) | predicted | A | — | 8 (best 0.80) |
Experiment against prediction
- 5YVH chain A against the predicted model Q92973: TM-score 0.98, RMSD 1.59 Å
- 5YVH chain A against the predicted model Q92973: TM-score 0.98, RMSD 1.59 Å
- 5YVI chain A against the predicted model Q92973: TM-score 0.97, RMSD 1.65 Å
- 5YVI chain A against the predicted model Q92973: TM-score 0.97, RMSD 1.65 Å
- 4FDD chain A against the predicted model Q92973: TM-score 0.97, RMSD 1.69 Å
- 4FDD chain A against the predicted model Q92973: TM-score 0.97, RMSD 1.69 Å
- 7CYL chain A against the predicted model Q92973: TM-score 0.97, RMSD 1.78 Å
- 7CYL chain A against the predicted model Q92973: TM-score 0.97, RMSD 1.78 Å
- 5J3V chain A against the predicted model Q92973: TM-score 0.97, RMSD 1.79 Å
- 5J3V chain A against the predicted model Q92973: TM-score 0.97, RMSD 1.79 Å
Elsewhere
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