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MolNFT v1 · #187925 · protein

GATOR1-rag-ragulator - inhibitory complex

7T3A: “GATOR1-rag-ragulator - inhibitory complex”. Electron microscopy, 1 ligand (GNP). MolNFT v1 #187925 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7T3A
Type
protein
Length
2,897 residues
Chains
10
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
O75140, Q8WTW4, Q12980, Q7L523, Q9HB90, Q6IAA8, Q9Y2Q5, Q9UHA4, Q0VGL1, O43504
Ligands
GNP

Structure

electron microscopy · 10 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein990—O75140
B—protein362—Q8WTW4
C—protein406—Q12980
K—protein294—Q7L523
L—protein299—Q9HB90
M—protein115—Q6IAA8
N—protein125—Q9Y2Q5
O—protein118—Q9UHA4
P—protein97—Q0VGL1
Q—protein91—O43504

Ligands and binding sites

  • GNP · Phosphoaminophosphonic acid-guanylate ester · ligand · chains K

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7T3A · GATOR1-RAG-RAGULATOR - Inhibitory Complex · the same entry in another collection · chain Q against Q, TM-score 1.00
  • O75140 · AlphaFold monomer V2.0 prediction for gator complex protein DEPDC5 (O75140) · a predicted model of the same protein · chain A against A, TM-score 0.98
  • Q7L523 · AlphaFold monomer V2.0 prediction for RAS-related GTP-binding protein a (Q7L523) · a predicted model of the same protein · chain K against A, TM-score 0.97

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