UniProt Q9UHA4
Ragulator complex protein LAMTOR3 (Q9UHA4)
Ragulator complex protein LAMTOR3 (UniProt Q9UHA4): 27 experimental structures and 1 predicted model on GenesisL1, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9UHA4
- Protein
- Ragulator complex protein LAMTOR3
- Experimental structures
- 27
- Predicted models
- 1
- Pockets
- 10 · 3 records with a druggable one
Structures
28 records of Q9UHA4 in the MolNFT archive: 27 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1SKO | MP1-p14 Complex | x-ray diffraction | A | — | — |
| 1SKO | MP1-P14 complex | x-ray diffraction | A | — | — |
| 2ZL1 | MP1-p14 Scaffolding complex | x-ray diffraction | A | — | — |
| 2ZL1 | MP1-P14 scaffolding complex | x-ray diffraction | A | — | — |
| 3CPT | MP1-p14 Scaffolding complex | x-ray diffraction | A | — | — |
| 3CPT | MP1-P14 scaffolding complex | x-ray diffraction | A | — | — |
| 5X6U | Crystal structure of human heteropentameric complex | x-ray diffraction | A | — | — |
| 5X6V | Crystal structure of human heteroheptameric complex | x-ray diffraction | A | — | — |
| 5Y39 | Crystal structure of Ragulator complex (p18 76-145) | x-ray diffraction | C, H | — | — |
| 5Y39 | Crystal structure of ragulator complex (P18 76-145) | x-ray diffraction | C, H | — | — |
| 5Y3A | Crystal structure of ragulator complex (P18 49-161) | x-ray diffraction | C, H | — | — |
| 5YK3 | human Ragulator complex | x-ray diffraction | m, C, H | — | — |
| 5YK3 | Human ragulator complex | x-ray diffraction | m, C, H | — | — |
| 6B9X | Crystal structure of ragulator | x-ray diffraction | C | — | — |
| 6EHP | The crystal structure of the human lamtor complex | x-ray diffraction | A | — | — |
| 6EHR | The crystal structure of the human lamtor-raga ctd-ragc ctd complex | x-ray diffraction | A | — | — |
| 6NZD | Cryo-EM structure of the lysosomal folliculin complex (flcn-FNIP2- raga-ragc-ragulator) | electron microscopy | C | — | — |
| 6U62 | Raptor-rag-ragulator complex | electron microscopy | F | — | — |
| 6ULG | Cryo-EM structure of the flcn-FNIP2-rag-ragulator complex | electron microscopy | A | — | — |
| 6WJ2 | CryoEM structure of the SLC38A9-RagA-RagC-Ragulator complex in the pre-GAP state | electron microscopy | C | — | 6 (best 0.77) |
| 6WJ2 | Cryoem structure of the SLC38A9-raga-ragc-ragulator complex in the pre-gap state | electron microscopy | C | — | — |
| 6WJ3 | CryoEM structure of the SLC38A9-RagA-RagC-Ragulator complex in the post-GAP state | electron microscopy | C | — | 3 (best 0.63) |
| 6WJ3 | Cryoem structure of the SLC38A9-raga-ragc-ragulator complex in the post-gap state | electron microscopy | C | — | — |
| 7T3A | GATOR1-rag-ragulator - inhibitory complex | electron microscopy | O | — | — |
| 7T3B | GATOR1-RAG-RAGULATOR - GAP Complex | electron microscopy | H | — | 1 (best 0.65) |
| 7T3B | GATOR1-rag-ragulator - gap complex | electron microscopy | H | — | — |
| 7T3C | GATOR1-rag-ragulator - dual complex | electron microscopy | H, O | — | — |
| Q9UHA4 | AlphaFold monomer V2.0 prediction for ragulator complex protein LAMTOR3 (Q9UHA4) | predicted | A | — | — |
Experiment against prediction
- 5Y39 chain H against the predicted model Q9UHA4: TM-score 0.99, RMSD 0.47 Å
- 5Y39 chain H against the predicted model Q9UHA4: TM-score 0.99, RMSD 0.47 Å
- 2ZL1 chain A against the predicted model Q9UHA4: TM-score 0.98, RMSD 0.57 Å
- 2ZL1 chain A against the predicted model Q9UHA4: TM-score 0.98, RMSD 0.57 Å
- 6EHP chain A against the predicted model Q9UHA4: TM-score 0.98, RMSD 0.66 Å
- 6B9X chain C against the predicted model Q9UHA4: TM-score 0.98, RMSD 0.67 Å
- 6NZD chain C against the predicted model Q9UHA4: TM-score 0.98, RMSD 0.67 Å
- 6EHR chain A against the predicted model Q9UHA4: TM-score 0.98, RMSD 0.69 Å
- 5Y3A chain C against the predicted model Q9UHA4: TM-score 0.97, RMSD 0.76 Å
- 5X6V chain A against the predicted model Q9UHA4: TM-score 0.97, RMSD 0.83 Å
Elsewhere
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