UniProt O75140
GATOR complex protein DEPDC5 (O75140)
GATOR complex protein DEPDC5 (UniProt O75140): 8 experimental structures and 1 predicted model on GenesisL1, 26 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O75140
- Protein
- GATOR complex protein DEPDC5
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 26 · 2 records with a druggable one
Structures
9 records of O75140 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6CES | Cryo-EM structure of GATOR1-RAG | electron microscopy | D | — | — |
| 6CES | Cryo-EM structure of GATOR1-rag | electron microscopy | D | — | — |
| 6CET | Cryo-EM structure of GATOR1 | electron microscopy | D | — | — |
| 7T3A | GATOR1-rag-ragulator - inhibitory complex | electron microscopy | A | — | — |
| 7T3B | GATOR1-RAG-RAGULATOR - GAP Complex | electron microscopy | A | — | 12 (best 0.80) |
| 7T3B | GATOR1-rag-ragulator - gap complex | electron microscopy | A | — | — |
| 7T3C | GATOR1-rag-ragulator - dual complex | electron microscopy | A | — | — |
| 8FW5 | Chimeric HsGATOR1-SpGtr-SpLam complex | electron microscopy | A | — | 14 (best 0.81) |
| O75140 | AlphaFold monomer V2.0 prediction for gator complex protein DEPDC5 (O75140) | predicted | A | — | — |
Experiment against prediction
- 7T3A chain A against the predicted model O75140: TM-score 0.98, RMSD 1.51 Å
- 7T3B chain A against the predicted model O75140: TM-score 0.98, RMSD 1.52 Å
- 7T3B chain A against the predicted model O75140: TM-score 0.98, RMSD 1.52 Å
- 7T3C chain A against the predicted model O75140: TM-score 0.97, RMSD 1.94 Å
- 8FW5 chain A against the predicted model O75140: TM-score 0.95, RMSD 2.42 Å
- 6CES chain D against the predicted model O75140: TM-score 0.82, RMSD 4.03 Å
- 6CES chain D against the predicted model O75140: TM-score 0.82, RMSD 4.03 Å
- 6CET chain D against the predicted model O75140: TM-score 0.81, RMSD 4.12 Å
Elsewhere
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