UniProt Q12980
GATOR complex protein NPRL3 (Q12980)
GATOR complex protein NPRL3 (UniProt Q12980): 11 experimental structures and 1 predicted model on GenesisL1, 66 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q12980
- Protein
- GATOR complex protein NPRL3
- Experimental structures
- 11
- Predicted models
- 1
- Pockets
- 66 · 12 records with a druggable one
Structures
12 records of Q12980 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6CES | Cryo-EM structure of GATOR1-RAG | electron microscopy | M | — | 7 (best 0.82) |
| 6CES | Cryo-EM structure of GATOR1-rag | electron microscopy | M | — | 7 (best 0.82) |
| 6CET | Cryo-EM structure of GATOR1 | electron microscopy | M | — | 10 (best 0.83) |
| 6CET | Cryo-EM structure of GATOR1 | electron microscopy | M | — | 10 (best 0.83) |
| 7T3A | GATOR1-RAG-RAGULATOR - Inhibitory Complex | electron microscopy | C | — | 5 (best 0.80) |
| 7T3A | GATOR1-rag-ragulator - inhibitory complex | electron microscopy | C | — | 5 (best 0.80) |
| 7T3B | GATOR1-RAG-RAGULATOR - GAP Complex | electron microscopy | C | — | 3 (best 0.75) |
| 7T3B | GATOR1-rag-ragulator - gap complex | electron microscopy | C | — | 3 (best 0.75) |
| 7T3C | GATOR1-RAG-RAGULATOR - Dual Complex | electron microscopy | C | — | 3 (best 0.77) |
| 7T3C | GATOR1-rag-ragulator - dual complex | electron microscopy | C | — | 3 (best 0.77) |
| 8FW5 | Chimeric HsGATOR1-SpGtr-SpLam complex | electron microscopy | C | — | 3 (best 0.77) |
| Q12980 | AlphaFold monomer V2.0 prediction for gator complex protein NPRL3 (Q12980) | predicted | A | — | 7 (best 0.52) |
Experiment against prediction
- 7T3A chain C against the predicted model Q12980: TM-score 0.85, RMSD 3.30 Å
- 7T3A chain C against the predicted model Q12980: TM-score 0.85, RMSD 3.30 Å
- 8FW5 chain C against the predicted model Q12980: TM-score 0.82, RMSD 3.60 Å
- 7T3C chain C against the predicted model Q12980: TM-score 0.82, RMSD 3.56 Å
- 7T3C chain C against the predicted model Q12980: TM-score 0.82, RMSD 3.56 Å
- 7T3B chain C against the predicted model Q12980: TM-score 0.81, RMSD 3.64 Å
- 7T3B chain C against the predicted model Q12980: TM-score 0.81, RMSD 3.64 Å
- 6CES chain M against the predicted model Q12980: TM-score 0.45, RMSD 5.61 Å
- 6CES chain M against the predicted model Q12980: TM-score 0.45, RMSD 5.61 Å
- 6CET chain M against the predicted model Q12980: TM-score 0.44, RMSD 5.49 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.