UniProt Q0VGL1
Ragulator complex protein LAMTOR4 (Q0VGL1)
Ragulator complex protein LAMTOR4 (UniProt Q0VGL1): 30 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 28 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q0VGL1
- Protein
- Ragulator complex protein LAMTOR4
- Experimental structures
- 30
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 28 · 7 records with a druggable one
Structures
31 records of Q0VGL1 in the MolNFT archive: 30 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5VOK | Crystal structure of the C7orf59-HBXIP dimer | x-ray diffraction | B, D, F, H | — | 9 (best 0.61) |
| 5VOK | Crystal structure of the C7ORF59-hbxip dimer | x-ray diffraction | B, D, F, H | — | — |
| 5X6U | Crystal structure of human heteropentameric complex | x-ray diffraction | D | — | — |
| 5X6V | Crystal structure of human heteroheptameric complex | x-ray diffraction | D | — | — |
| 5Y38 | Crystal structure of C7orf59-HBXIP complex | x-ray diffraction | B | SO4 | — |
| 5Y38 | Crystal structure of C7ORF59-hbxip complex | x-ray diffraction | B | SO4 | — |
| 5Y39 | Crystal structure of Ragulator complex (p18 76-145) | x-ray diffraction | D, I | — | — |
| 5Y39 | Crystal structure of ragulator complex (P18 76-145) | x-ray diffraction | D, I | — | — |
| 5Y3A | Crystal structure of ragulator complex (P18 49-161) | x-ray diffraction | D, I | SO4 | — |
| 5YK3 | human Ragulator complex | x-ray diffraction | n, D, I | — | — |
| 5YK3 | Human ragulator complex | x-ray diffraction | n, D, I | — | — |
| 5YK5 | structure of the human Lamtor4-Lamtor5 complex | x-ray diffraction | A, C | — | 1 (best 0.49) |
| 5YK5 | Structure of the human LAMTOR4-LAMTOR5 complex | x-ray diffraction | A, C | — | — |
| 6B9X | Crystal structure of ragulator | x-ray diffraction | D | — | — |
| 6EHP | The crystal structure of the human lamtor complex | x-ray diffraction | D | CL | — |
| 6EHR | The crystal structure of the human lamtor-raga ctd-ragc ctd complex | x-ray diffraction | D | — | — |
| 6NZD | Cryo-EM Structure of the Lysosomal Folliculin Complex (FLCN-FNIP2-RagA-RagC-Ragulator) | electron microscopy | D | — | 3 (best 0.66) |
| 6NZD | Cryo-EM structure of the lysosomal folliculin complex (flcn-FNIP2- raga-ragc-ragulator) | electron microscopy | D | — | — |
| 6U62 | Raptor-Rag-Ragulator complex | electron microscopy | G | — | 2 (best 0.77) |
| 6U62 | Raptor-rag-ragulator complex | electron microscopy | G | — | — |
| 6ULG | Cryo-EM structure of the FLCN-FNIP2-Rag-Ragulator complex | electron microscopy | D | — | 2 (best 0.68) |
| 6ULG | Cryo-EM structure of the flcn-FNIP2-rag-ragulator complex | electron microscopy | D | — | — |
| 6WJ2 | CryoEM structure of the SLC38A9-RagA-RagC-Ragulator complex in the pre-GAP state | electron microscopy | D | — | 5 (best 0.73) |
| 6WJ2 | Cryoem structure of the SLC38A9-raga-ragc-ragulator complex in the pre-gap state | electron microscopy | D | — | — |
| 6WJ3 | CryoEM structure of the SLC38A9-RagA-RagC-Ragulator complex in the post-GAP state | electron microscopy | D | — | 3 (best 0.63) |
| 6WJ3 | Cryoem structure of the SLC38A9-raga-ragc-ragulator complex in the post-gap state | electron microscopy | D | — | — |
| 7T3A | GATOR1-rag-ragulator - inhibitory complex | electron microscopy | P | — | — |
| 7T3B | GATOR1-RAG-RAGULATOR - GAP Complex | electron microscopy | I | — | 3 (best 0.73) |
| 7T3B | GATOR1-rag-ragulator - gap complex | electron microscopy | I | — | — |
| 7T3C | GATOR1-rag-ragulator - dual complex | electron microscopy | I, P | — | — |
| Q0VGL1 | AlphaFold monomer V2.0 prediction for ragulator complex protein LAMTOR4 (Q0VGL1) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5X6V chain D against the predicted model Q0VGL1: TM-score 0.96, RMSD 0.74 Å
- 6B9X chain D against the predicted model Q0VGL1: TM-score 0.94, RMSD 1.17 Å
- 6NZD chain D against the predicted model Q0VGL1: TM-score 0.94, RMSD 1.17 Å
- 6NZD chain D against the predicted model Q0VGL1: TM-score 0.94, RMSD 1.17 Å
- 5Y3A chain I against the predicted model Q0VGL1: TM-score 0.94, RMSD 1.41 Å
- 5Y38 chain B against the predicted model Q0VGL1: TM-score 0.93, RMSD 0.95 Å
- 5Y38 chain B against the predicted model Q0VGL1: TM-score 0.93, RMSD 0.95 Å
- 6ULG chain D against the predicted model Q0VGL1: TM-score 0.93, RMSD 0.97 Å
- 6ULG chain D against the predicted model Q0VGL1: TM-score 0.93, RMSD 0.97 Å
- 5Y3A chain D against the predicted model Q0VGL1: TM-score 0.92, RMSD 1.25 Å
Elsewhere
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