UniProt Q15691
Microtubule-associated protein RP/EB family member 1 (Q15691)
Microtubule-associated protein RP/EB family member 1 (UniProt Q15691): 58 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 19 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q15691
- Protein
- Microtubule-associated protein RP/EB family member 1
- Experimental structures
- 58
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 19 · 3 records with a druggable one
Structures
59 records of Q15691 in the MolNFT archive: 58 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1PA7 | Crystal structure of amino-terminal microtubule binding domain of EB1 | x-ray diffraction | A | — | — |
| 1PA7 | Crystal structure of amino-terminal microtubule binding domain of EB1 | x-ray diffraction | A | — | — |
| 1TXQ | Crystal structure of the EB1 C-terminal domain complexed with the CAP-Gly domain of p150Glued | x-ray diffraction | B | — | — |
| 1TXQ | Crystal structure of the EB1 C-terminal domain complexed with the cap-gly domain of P150GLUED | x-ray diffraction | B | — | — |
| 1UEG | Crystal structure of amino-terminal microtubule binding domain of EB1 | x-ray diffraction | A | — | — |
| 1UEG | Crystal structure of amino-terminal microtubule binding domain of EB1 | x-ray diffraction | A | — | — |
| 1VKA | Southeast Collaboratory for Structural Genomics: Hypothetical Human Protein Q15691 N-Terminal… | x-ray diffraction | A, B | — | — |
| 1VKA | Southeast collaboratory for structural genomics: hypothetical human protein Q15691 N-terminal… | x-ray diffraction | A, B | — | — |
| 1WU9 | Crystal structure of the C-terminal domain of the end-binding protein 1 (EB1) | x-ray diffraction | A, B | — | — |
| 1WU9 | Crystal structure of the C-terminal domain of the end-binding protein 1 (EB1) | x-ray diffraction | A, B | — | — |
| 1YIB | Crystal Structure of the Human EB1 C-terminal Dimerization Domain | x-ray diffraction | A | — | — |
| 1YIB | Crystal structure of the human EB1 C-terminal dimerization domain | x-ray diffraction | A | — | — |
| 1YIG | Crystal Structure of the Human EB1 C-terminal Dimerization Domain | x-ray diffraction | A, B | — | — |
| 1YIG | Crystal structure of the human EB1 C-terminal dimerization domain | x-ray diffraction | A, B | — | — |
| 2HKQ | Crystal structure of the C-terminal domain of human EB1 in complex with the CAP-Gly domain of human… | x-ray diffraction | A | — | — |
| 2HKQ | Crystal structure of the C-terminal domain of human EB1 in complex with the cap-gly domain of human… | x-ray diffraction | A | — | — |
| 2HL3 | Crystal structure of the A49M mutant CAP-Gly domain of human Dynactin-1 (p150-Glued) in complex… | x-ray diffraction | C | — | 1 (best 0.44) |
| 2HL3 | Crystal structure of the A49M mutant cap-gly domain of human dynactin- 1 (P150-glued) in complex… | x-ray diffraction | C | — | — |
| 2HL5 | Crystal structure of the C-terminal domain of human EB1 in complex with the A49M mutant CAP-Gly… | x-ray diffraction | A, B | — | — |
| 2HL5 | Crystal structure of the C-terminal domain of human EB1 in complex with the A49M mutant cap-gly… | x-ray diffraction | A, B | — | — |
| 2QJZ | Structural Basis of Microtubule Plus End Tracking by XMAP215, CLIP-170 and EB1 | x-ray diffraction | A, B | — | — |
| 2QJZ | Structural basis of microtubule plus end tracking by XMAP215, clip-170 and EB1 | x-ray diffraction | A, B | — | — |
| 2R8U | Structure of fragment of human end-binding protein 1 (EB1) containing the N-terminal domain at 1.35… | x-ray diffraction | A, B | — | — |
| 2R8U | Structure of fragment of human end-binding protein 1 (EB1) containing the N-terminal domain at 1.35… | x-ray diffraction | A, B | — | — |
| 3GJO | Crystal structure of human EB1 in complex with microtubule Tip localization signal peptide of MACF | x-ray diffraction | A, B, C, D | — | — |
| 3GJO | Crystal structure of human EB1 in complex with microtubule tip localization signal peptide of macf | x-ray diffraction | A, B, C, D | — | — |
| 3MTU | Structure of the Tropomyosin Overlap Complex from Chicken Smooth Muscle | x-ray diffraction | A, B, C, D | — | — |
| 3MTU | Structure of the tropomyosin overlap complex from chicken smooth muscle | x-ray diffraction | A, B, C, D | — | — |
| 3MUD | Structure of the Tropomyosin Overlap Complex from Chicken Smooth Muscle | x-ray diffraction | C, D | — | — |
| 3MUD | Structure of the tropomyosin overlap complex from chicken smooth muscle | x-ray diffraction | C, D | — | — |
| 3TQ7 | EB1c/EB3c heterodimer in complex with the CAP-Gly domain of P150glued | x-ray diffraction | A | — | — |
| 3TQ7 | EB1C/EB3C heterodimer in complex with the cap-gly domain of P150GLUED | x-ray diffraction | A | — | — |
| 4XA1 | Crystal Structure of the coiled-coil surrounding Skip 1 of MYH7 | x-ray diffraction | A, B, C, D | — | — |
| 4XA1 | Crystal structure of the coiled-coil surrounding skip 1 of MYH7 | x-ray diffraction | A, B, C, D | — | — |
| 4XA3 | Crystal structure of the coiled-coil surrounding Skip 2 of MYH7 | x-ray diffraction | A, B | — | — |
| 4XA3 | Crystal structure of the coiled-coil surrounding skip 2 of MYH7 | x-ray diffraction | A, B | — | — |
| 4XA6 | Crystal Structure of the coiled-coil surrounding Skip 4 of MYH7 | x-ray diffraction | A, B, C, D | — | — |
| 4XA6 | Crystal structure of the coiled-coil surrounding skip 4 of MYH7 | x-ray diffraction | A, B, C, D | — | — |
| 5JV3 | The neck-linker and alpha 7 helix of Homo sapiens Eg5 fused to EB1 | x-ray diffraction | A, B, C, D | CA | — |
| 5JV3 | The neck-linker and alpha 7 helix of homo sapiens EG5 fused to EB1 | x-ray diffraction | A, B, C, D | — | — |
| 5JVM | The neck-linker and alpha 7 helix of Mus musculus KIF3C | x-ray diffraction | A, B | — | — |
| 5JVM | The neck-linker and alpha 7 helix of mus musculus KIF3C | x-ray diffraction | A, B | MG | — |
| 5JVP | The neck-linker and alpha 7 helix of Homo sapiens CENP-E | x-ray diffraction | A, B, C, D, E, F | CD | — |
| 5JVP | The neck-linker and alpha 7 helix of homo sapiens cenp-E | x-ray diffraction | A, B, C, D, E, F | CD | 1 (best 0.38) |
| 5JVR | The neck-linker of Mus musculus KIF3A fused to the alpha 7 helix of Drosophila melanogaster… | x-ray diffraction | A, B, C, D, E, F, G, H | — | 8 (best 0.73) |
| 5JVR | The neck-linker of mus musculus KIF3A fused to the alpha 7 helix of drosophila melanogaster… | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 5JVS | The neck-linker + DAL and alpha 7 helix of Drosophila melanogaster Kinesin-1 fused to EB1 | x-ray diffraction | A | — | — |
| 5JVS | The neck-linker + dal and alpha 7 helix of drosophila melanogaster kinesin-1 fused to EB1 | x-ray diffraction | A | — | — |
| 5JVU | The neck-linker and alpha 7 helix of Drosophila melanogaster kinesin-1 fused to EB1 | x-ray diffraction | A, B | — | 1 (best 0.35) |
| 5JVU | The neck-linker and alpha 7 helix of drosophila melanogaster kinesin-1 fused to EB1 | x-ray diffraction | A, B | — | — |
| 5JX1 | The neck-linker and alpha 7 helix of Mus musculus KIF3A fused to EB1 | x-ray diffraction | A | — | — |
| 5JX1 | The neck-linker and alpha 7 helix of mus musculus KIF3A fused to EB1 | x-ray diffraction | A | — | — |
| 5N74 | Microtubule end binding protein complex | x-ray diffraction | A, B, C, D, E, F, G, H | — | 5 (best 0.71) |
| 5N74 | Microtubule end binding protein complex | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 5WLQ | Crystal Structure of Amino Acids 1677-1755 of Human Beta Cardiac Myosin Fused to Gp7 and Eb1 | x-ray diffraction | A | TMO | — |
| 5WLQ | Crystal structure of amino acids 1677-1755 of human beta cardiac myosin fused to GP7 and EB1 | x-ray diffraction | A | TMO | — |
| 6YF5 | Lamin a 17-70 COIL1A dimer stabilized by C-terminal capping | x-ray diffraction | A, B, C, D | — | — |
| 6YSH | Lamin a 1-70 COIL1A dimer stabilized by C-terminal capping | x-ray diffraction | A, B | — | — |
| Q15691 | AlphaFold monomer V2.0 prediction for microtubule-associated protein RP/EB family member 1 (Q15691) | predicted | A | — | 3 (best 0.53) |
Ligands
Experiment against prediction
- 2HL3 chain C against the predicted model Q15691: TM-score 1.00, RMSD 0.03 Å
- 2HL3 chain C against the predicted model Q15691: TM-score 1.00, RMSD 0.03 Å
- 1UEG chain A against the predicted model Q15691: TM-score 0.98, RMSD 0.72 Å
- 1UEG chain A against the predicted model Q15691: TM-score 0.98, RMSD 0.72 Å
- 2QJZ chain A against the predicted model Q15691: TM-score 0.97, RMSD 1.03 Å
- 2QJZ chain A against the predicted model Q15691: TM-score 0.97, RMSD 1.03 Å
- 2QJZ chain B against the predicted model Q15691: TM-score 0.97, RMSD 0.91 Å
- 2QJZ chain B against the predicted model Q15691: TM-score 0.97, RMSD 0.91 Å
- 2R8U chain A against the predicted model Q15691: TM-score 0.97, RMSD 1.16 Å
- 2R8U chain A against the predicted model Q15691: TM-score 0.97, RMSD 1.16 Å
Elsewhere
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