MolNFT v1 · #25259 · protein
Southeast collaboratory for structural genomics: hypothetical human protein Q15691 N-terminal fragment
1VKA · Microtubule-associated protein RP/EB family member 1: “Southeast collaboratory for structural genomics: hypothetical human protein Q15691 N-terminal fragment”. X-ray diffraction, 2 pockets (best druggability 0.40). MolNFT v1 #25259…
- PDB
- 1VKA
- Type
- protein
- Length
- 260 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Microtubule-associated protein RP/EB family member 1
- UniProt
- Q15691
- Pockets
- 2 · best druggability 0.40
Structure
x-ray diffraction · 2 distinct chains · 58% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Microtubule-associated protein RP/EB family member 1 | protein | 131 | 59% helix, 0% strand | Q15691 |
| B | Microtubule-associated protein RP/EB family member 1 | protein | 129 | 58% helix, 0% strand | Q15691 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 78 | 0.40 | 0.78 | 19 | empty |
| 2 | 61 | 0.33 | 0.77 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 211 Ų buried · 4 hydrogen bonds · protein-protein
Compared structures
- 1VKA · Southeast Collaboratory for Structural Genomics: Hypothetical Human Protein Q15691… · the same entry in another collection · chain A against A, TM-score 1.00
- Q15691 · AlphaFold monomer V2.0 prediction for microtubule-associated protein RP/EB family member… · a predicted model of the same protein · chain B against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q15691
- Elsewhere: RCSB PDB 1VKA · PDBe 1VKA · UniProt Q15691
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