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Southeast collaboratory for structural genomics: hypothetical human protein Q15691 N-terminal fragment

Analyse Southeast collaboratory for structural genomics: hypothetical human protein… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
1VKA
Type
protein
Length
260 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Microtubule-associated protein RP/EB family member 1
UniProt
Q15691
Pockets
2 · best druggability 0.40

Structure

x-ray diffraction · 2 distinct chains · 58% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AMicrotubule-associated protein RP/EB family member 1protein13159% helix, 0% strandQ15691
BMicrotubule-associated protein RP/EB family member 1protein12958% helix, 0% strandQ15691

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1780.400.7819empty
2610.330.7715empty

Interfaces

1 interface between chains.

  • A–B · 211 Ų buried · 4 hydrogen bonds · protein-protein

Compared structures

  • 1VKA · Southeast Collaboratory for Structural Genomics: Hypothetical Human Protein Q15691… · the same entry in another collection · chain A against A, TM-score 1.00
  • Q15691 · AlphaFold monomer V2.0 prediction for microtubule-associated protein RP/EB family member… · a predicted model of the same protein · chain B against A, TM-score 0.97

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