MolNFT v1 · #171075 · protein
Lamin a 1-70 COIL1A dimer stabilized by C-terminal capping
6YSH · Prelamin-A/C,MICROTUBULE-associated protein RP/EB family…: “Lamin a 1-70 COIL1A dimer stabilized by C-terminal capping”. X-ray diffraction, 1 pocket (best druggability 0.30). MolNFT v1 #171075 on GenesisL1: 3D structure, binding…
- PDB
- 6YSH
- Type
- protein
- Length
- 164 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Prelamin-A/C,MICROTUBULE-associated protein RP/EB family member 1
- UniProt
- P02545, Q15691
- Pockets
- 1 · best druggability 0.30
Structure
x-ray diffraction · 2 distinct chains · 85% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Prelamin-A/C,MICROTUBULE-associated protein RP/EB family member 1 | protein | 83 | 84% helix, 0% strand | P02545, Q15691 |
| B | Prelamin-A/C,MICROTUBULE-associated protein RP/EB family member 1 | protein | 81 | 86% helix, 0% strand | P02545, Q15691 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 50 | 0.30 | 0.75 | 9 | empty |
Interfaces
1 interface between chains.
- A–B · 1894 Ų buried · 19 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P02545
- Every structure of UniProt Q15691
- Elsewhere: RCSB PDB 6YSH · PDBe 6YSH · UniProt P02545 · UniProt Q15691
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