UniProt P28000
DNA-directed RNA polymerases I and III subunit RPAC2 (P28000)
DNA-directed RNA polymerases I and III subunit RPAC2 (UniProt P28000): 74 experimental structures on GenesisL1, 1 ligand bound, 8 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P28000
- Protein
- DNA-directed RNA polymerases I and III subunit RPAC2
- Experimental structures
- 74
- Predicted models
- 0
- Ligands
- 1
- Pockets
- 8 · 6 records with a druggable one
Structures
74 records of P28000 in the MolNFT archive: 74 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4C2M | Structure of RNA polymerase I at 2.8 A resolution | x-ray diffraction | K, Z | — | — |
| 4C2M | Structure of RNA polymerase I at 2.8 a resolution | x-ray diffraction | K, Z | — | — |
| 4C3H | Structure of 14-subunit RNA polymerase I at 3.27 A resolution, crystal form C2-93 | x-ray diffraction | K | — | — |
| 4C3H | Structure of 14-subunit RNA polymerase I at 3.27 a resolution, crystal form C2-93 | x-ray diffraction | K | — | — |
| 4C3I | Structure of 14-subunit RNA polymerase I at 3.0 A resolution, crystal form C2-100 | x-ray diffraction | K | — | — |
| 4C3I | Structure of 14-subunit RNA polymerase I at 3.0 a resolution, crystal form C2-100 | x-ray diffraction | K | — | — |
| 4C3J | Structure of 14-subunit RNA polymerase I at 3.35 A resolution, crystal form C2-90 | x-ray diffraction | K | — | — |
| 4C3J | Structure of 14-subunit RNA polymerase I at 3.35 a resolution, crystal form C2-90 | x-ray diffraction | K | — | — |
| 5FJ8 | Cryo-EM structure of yeast RNA polymerase III elongation complex at 3. 9 A | electron microscopy | K | — | — |
| 5FJ8 | Cryo-EM structure of yeast RNA polymerase III elongation complex at 3. 9 a | electron microscopy | K | — | — |
| 5FJ9 | Cryo-EM structure of yeast apo RNA polymerase III at 4.6 A | electron microscopy | K | — | — |
| 5FJ9 | Cryo-EM structure of yeast apo RNA polymerase III at 4.6 a | electron microscopy | K | — | — |
| 5FJA | Cryo-EM structure of yeast RNA polymerase III at 4.7 a | electron microscopy | K | — | — |
| 5G5L | RNA polymerase I-RRN3 complex at 4.8 a resolution | electron microscopy | K | — | — |
| 5LMX | Monomeric RNA polymerase I at 4.9 a resolution | electron microscopy | K | — | — |
| 5M3F | Yeast RNA polymerase I elongation complex at 3.8A | electron microscopy | K | — | — |
| 5M3M | Free monomeric RNA polymerase I at 4.0A resolution | electron microscopy | K | — | — |
| 5M3M | Free monomeric RNA polymerase I at 4.0A resolution | electron microscopy | K | — | — |
| 5M5W | RNA polymerase I open complex | electron microscopy | K | — | — |
| 5M5X | RNA Polymerase I elongation complex 1 | electron microscopy | K | — | — |
| 5M5X | RNA polymerase I elongation complex 1 | electron microscopy | K | — | — |
| 5M5Y | RNA polymerase I elongation complex 2 | electron microscopy | K | — | — |
| 5M64 | RNA polymerase I elongation complex with A49 tandem winged helix domain | electron microscopy | K | — | — |
| 5N5Y | Cryo-EM structure of RNA polymerase I in complex with RRN3 and core factor (orientation III) | electron microscopy | K | — | — |
| 5N5Z | Cryo-EM structure of RNA polymerase I in complex with Rrn3 and Core Factor (Orientation II) | electron microscopy | K | — | 1 (best 0.82) |
| 5N5Z | Cryo-EM structure of RNA polymerase I in complex with RRN3 and core factor (orientation II) | electron microscopy | K | — | — |
| 5N60 | Cryo-EM structure of RNA polymerase I in complex with RRN3 and core factor (orientation I) | electron microscopy | K | — | — |
| 5N61 | RNA polymerase I initially transcribing complex | electron microscopy | K | — | — |
| 5OA1 | RNA polymerase I pre-initiation complex | electron microscopy | K | — | — |
| 5W5Y | RNA polymerase I initial transcribing complex | electron microscopy | K | — | — |
| 5W64 | RNA polymerase I initial transcribing complex state 1 | electron microscopy | K | — | — |
| 5W65 | RNA polymerase I initial transcribing complex state 2 | electron microscopy | K | — | — |
| 5W66 | RNA polymerase I initial transcribing complex state 3 | electron microscopy | K | — | — |
| 6CNB | Yeast RNA polymerase III initial transcribing complex | electron microscopy | K | — | — |
| 6CNC | Yeast RNA polymerase III open complex | electron microscopy | K | — | — |
| 6CND | Yeast RNA polymerase III natural open complex (noc) | electron microscopy | K | — | — |
| 6CNF | Yeast RNA polymerase III elongation complex | electron microscopy | K | — | — |
| 6EU0 | RNA polymerase III open pre-initiation complex (oc-pic) | electron microscopy | K | — | — |
| 6EU1 | RNA Polymerase III - open DNA complex (OC-POL3). | electron microscopy | K | — | — |
| 6EU1 | RNA polymerase III - open DNA complex (oc-POL3). | electron microscopy | K | — | — |
| 6EU2 | Apo RNA polymerase III - open conformation (OPOL3) | electron microscopy | K | — | — |
| 6EU3 | Apo RNA polymerase III - closed conformation (CPOL3) | electron microscopy | K | — | — |
| 6F40 | RNA polymerase III open complex | electron microscopy | K | — | — |
| 6F41 | RNA Polymerase III initially transcribing complex | electron microscopy | K | — | 1 (best 0.88) |
| 6F41 | RNA polymerase III initially transcribing complex | electron microscopy | K | — | — |
| 6F42 | RNA polymerase III closed complex CC1. | electron microscopy | K | — | — |
| 6F44 | RNA Polymerase III closed complex CC2. | electron microscopy | K | — | 1 (best 0.86) |
| 6F44 | RNA polymerase III closed complex CC2. | electron microscopy | K | — | — |
| 6H67 | Yeast RNA polymerase I elongation complex stalled by cyclobutane pyrimidine dimer (CPD) | electron microscopy | K | — | — |
| 6H67 | Yeast RNA polymerase I elongation complex stalled by cyclobutane pyrimidine dimer (cpd) | electron microscopy | K | — | — |
| 6H68 | Yeast RNA polymerase I elongation complex stalled by cyclobutane pyrimidine dimer (CPD) with… | electron microscopy | K | — | — |
| 6H68 | Yeast RNA polymerase I elongation complex stalled by cyclobutane pyrimidine dimer (cpd) with… | electron microscopy | K | — | — |
| 6HKO | Yeast RNA polymerase I elongation complex bound to nucleotide analog GMPCPP | electron microscopy | K | — | — |
| 6HKO | Yeast RNA polymerase I elongation complex bound to nucleotide analog gmpcpp | electron microscopy | K | — | — |
| 6HLQ | Yeast RNA polymerase I* elongation complex bound to nucleotide analog GMPCPP | electron microscopy | K | — | — |
| 6HLQ | Yeast RNA polymerase I* elongation complex bound to nucleotide analog gmpcpp | electron microscopy | K | — | — |
| 6HLR | Yeast RNA polymerase I elongation complex bound to nucleotide analog gmpcpp (core focused) | electron microscopy | K | — | — |
| 6HLS | Yeast apo RNA polymerase I* | electron microscopy | K | — | — |
| 6HLS | Yeast apo RNA polymerase I* | electron microscopy | K | — | — |
| 6RQH | RNA Polymerase I Closed Conformation 1 (CC1) | electron microscopy | K | — | — |
14 records more on the page itself.
Ligands
- 4QM · (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol · in 1 record
Elsewhere
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