MolNFT v1 · #138019 · protein + DNA + RNA
RNA polymerase I initial transcribing complex state 2
5W65: “RNA polymerase I initial transcribing complex state 2”. Electron microscopy, 1 ligand (ZN). MolNFT v1 #138019 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5W65
- Type
- protein + DNA + RNA
- Length
- 5,757 residues
- Chains
- 20
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P10964, P22138, P07703, P50106, P20434, P20435, P46669, P20436, P32529, P22139, P28000, P40422, Q01080, P47006, P32786, P40992, Q04712
- Ligands
- ZN
Structure
electron microscopy · 20 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 1461 | — | P10964 |
| B | — | protein | 1178 | — | P22138 |
| C | — | protein | 306 | — | P07703 |
| D | — | protein | 59 | — | P50106 |
| E | — | protein | 215 | — | P20434 |
| F | — | protein | 83 | — | P20435 |
| G | — | protein | 201 | — | P46669 |
| H | — | protein | 133 | — | P20436 |
| I | — | protein | 65 | — | P32529 |
| J | — | protein | 69 | — | P22139 |
| K | — | protein | 103 | — | P28000 |
| L | — | protein | 45 | — | P40422 |
| M | — | protein | 106 | — | Q01080 |
| N | — | protein | 158 | — | P47006 |
| O | — | protein | 640 | — | P32786 |
| P | — | protein | 481 | — | P40992 |
| Q | — | protein | 349 | — | Q04712 |
| R | — | rna | 6 | — | — |
| S | — | dna | 45 | — | — |
| T | — | dna | 54 | — | — |
Ligands and binding sites
- ZN · Zinc ion · metal · 7 copies · chains A, B, I, J, L, P
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- P22138 · AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase I subunit RPA135… · a predicted model of the same protein · chain B against A, TM-score 0.98
- P10964 · AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase I subunit RPA190… · a predicted model of the same protein · chain A against A, TM-score 0.97
- P07703 · AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerases I and III subunit… · a predicted model of the same protein · chain C against A, TM-score 0.96
- P28000 · AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerases I and III subunit… · a predicted model of the same protein · chain K against A, TM-score 0.96
- P32786 · AlphaFold monomer V2.0 prediction for RNA polymerase I-specific transcription initiation… · a predicted model of the same protein · chain O against A, TM-score 0.90
- P46669 · AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase I subunit RPA43 (P46669) · a predicted model of the same protein · chain G against A, TM-score 0.90
- Q01080 · AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase I subunit RPA49 (Q01080) · a predicted model of the same protein · chain M against A, TM-score 0.84
- P50106 · AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase I subunit RPA14 (P50106) · a predicted model of the same protein · chain D against A, TM-score 0.79
- P40992 · AlphaFold monomer V2.0 prediction for RNA polymerase I-specific transcription initiation… · a predicted model of the same protein · chain P against A, TM-score 0.76
- P32529 · AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase I subunit RPA12 (P32529) · a predicted model of the same protein · chain I against A, TM-score 0.70
- Q04712 · AlphaFold monomer V2.0 prediction for RNA polymerase I-specific transcription initiation… · a predicted model of the same protein · chain Q against A, TM-score 0.70
- P47006 · AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase I subunit RPA34 (P47006) · a predicted model of the same protein · chain N against A, TM-score 0.66
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P10964
- Every structure of UniProt P22138
- Every structure of UniProt P07703
- Every structure of UniProt P50106
- Every structure of UniProt P20434
- Every structure of UniProt P20435
- Every structure of UniProt P46669
- Every structure of UniProt P20436
- Every structure of UniProt P32529
- Every structure of UniProt P22139
- Every structure of UniProt P28000
- Every structure of UniProt P40422
- Every structure of UniProt Q01080
- Every structure of UniProt P47006
- Every structure of UniProt P32786
- Every structure of UniProt P40992
- Every structure of UniProt Q04712
- Elsewhere: RCSB PDB 5W65 · PDBe 5W65 · UniProt P10964 · UniProt P22138 · UniProt P07703 · UniProt P50106 · UniProt P20434 · UniProt P20435 · UniProt P46669 · UniProt P20436 · UniProt P32529 · UniProt P22139 · UniProt P28000 · UniProt P40422 · UniProt Q01080 · UniProt P47006 · UniProt P32786 · UniProt P40992 · UniProt Q04712
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.