UniProt P20436
DNA-directed RNA polymerases I, II, and III subunit RPABC3 (P20436)
DNA-directed RNA polymerases I, II, and III subunit RPABC3 (UniProt P20436), EC 2.7.7.6: 427 experimental structures and 1 predicted model on GenesisL1, 755 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P20436
- Protein
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- EC
- 2.7.7.6
- Experimental structures
- 427
- Predicted models
- 1
- Pockets
- 755 · 336 records with a druggable one
Structures
428 records of P20436 in the MolNFT archive: 427 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1A1D | Yeast RNA polymerase subunit RPB8, NMR, minimized average structure, alpha carbons only | solution nmr | A | — | — |
| 1A1D | Yeast RNA polymerase subunit RPB8, NMR, minimized average structure, alpha carbons only | solution nmr | A | — | — |
| 1I3Q | RNA polymerase II crystal form I at 3.1 a resolution | x-ray diffraction | H | — | 2 (best 0.89) |
| 1I3Q | RNA polymerase II crystal form I at 3.1 a resolution | x-ray diffraction | H | — | 2 (best 0.89) |
| 1I50 | RNA polymerase II crystal form II at 2.8 a resolution | x-ray diffraction | H | — | 2 (best 0.88) |
| 1I50 | RNA polymerase II crystal form II at 2.8 a resolution | x-ray diffraction | H | — | 2 (best 0.88) |
| 1I6H | RNA polymerase II elongation complex | x-ray diffraction | H | — | 2 (best 0.89) |
| 1I6H | RNA polymerase II elongation complex | x-ray diffraction | H | — | 2 (best 0.89) |
| 1K83 | Crystal Structure of Yeast RNA Polymerase II Complexed with the Inhibitor Alpha Amanitin | x-ray diffraction | H | — | 2 (best 0.89) |
| 1K83 | Crystal structure of yeast RNA polymerase II complexed with the inhibitor alpha amanitin | x-ray diffraction | H | — | 2 (best 0.89) |
| 1NIK | Wild Type RNA Polymerase II | x-ray diffraction | H | — | 4 (best 0.88) |
| 1NIK | Wild type RNA polymerase II | x-ray diffraction | H | — | 4 (best 0.88) |
| 1NT9 | Complete 12-subunit RNA polymerase II | x-ray diffraction | H | — | — |
| 1NT9 | Complete 12-subunit RNA polymerase II | x-ray diffraction | H | — | — |
| 1PQV | RNA polymerase II-TFIIS complex | x-ray diffraction | H | — | — |
| 1PQV | RNA polymerase II-tfiis complex | x-ray diffraction | H | — | — |
| 1R5U | RNA polymerase II tfiib complex | x-ray diffraction | H | — | 3 (best 0.89) |
| 1R5U | RNA polymerase II tfiib complex | x-ray diffraction | H | — | 3 (best 0.89) |
| 1R9S | RNA polymerase II strand separated elongation complex, matched nucleotide | x-ray diffraction | H | — | 2 (best 0.89) |
| 1R9S | RNA polymerase II strand separated elongation complex, matched nucleotide | x-ray diffraction | H | — | 2 (best 0.89) |
| 1R9T | RNA polymerase II strand separated elongation complex, mismatched nucleotide | x-ray diffraction | H | — | 3 (best 0.89) |
| 1R9T | RNA polymerase II strand separated elongation complex, mismatched nucleotide | x-ray diffraction | H | — | 3 (best 0.89) |
| 1SFO | RNA polymerase II strand separated elongation complex | x-ray diffraction | H | — | 2 (best 0.88) |
| 1SFO | RNA polymerase II strand separated elongation complex | x-ray diffraction | H | — | 2 (best 0.88) |
| 1TWA | RNA polymerase II complexed with ATP | x-ray diffraction | H | — | 2 (best 0.88) |
| 1TWA | RNA polymerase II complexed with ATP | x-ray diffraction | H | — | 2 (best 0.88) |
| 1TWC | RNA polymerase II complexed with GTP | x-ray diffraction | H | — | 2 (best 0.88) |
| 1TWC | RNA polymerase II complexed with GTP | x-ray diffraction | H | — | 2 (best 0.88) |
| 1TWF | RNA polymerase II complexed with UTP at 2.3 A resolution | x-ray diffraction | H | — | 2 (best 0.88) |
| 1TWF | RNA polymerase II complexed with UTP at 2.3 a resolution | x-ray diffraction | H | — | 2 (best 0.88) |
| 1TWG | RNA polymerase II complexed with CTP | x-ray diffraction | H | — | 2 (best 0.88) |
| 1TWG | RNA polymerase II complexed with CTP | x-ray diffraction | H | — | 2 (best 0.88) |
| 1TWH | RNA polymerase II complexed with 2'dATP | x-ray diffraction | H | — | 2 (best 0.88) |
| 1TWH | RNA polymerase II complexed with 2'DATP | x-ray diffraction | H | — | 2 (best 0.88) |
| 1WCM | Complete 12-Subunit RNA Polymerase II at 3.8 Angstrom | x-ray diffraction | H | — | 3 (best 0.88) |
| 1WCM | Complete 12-subunit RNA polymerase II at 3.8 ang | x-ray diffraction | H | — | 3 (best 0.88) |
| 1Y1V | Refined RNA Polymerase II-TFIIS complex | x-ray diffraction | H | — | 3 (best 0.89) |
| 1Y1V | Refined RNA polymerase II-tfiis complex | x-ray diffraction | H | — | 3 (best 0.89) |
| 1Y1W | Complete RNA Polymerase II elongation complex | x-ray diffraction | H | — | 2 (best 0.84) |
| 1Y1W | Complete RNA polymerase II elongation complex | x-ray diffraction | H | — | 2 (best 0.84) |
| 1Y1Y | RNA Polymerase II-TFIIS-DNA/RNA complex | x-ray diffraction | H | — | — |
| 1Y1Y | RNA polymerase II-tfiis-DNA/RNA complex | x-ray diffraction | H | — | — |
| 1Y77 | Complete RNA Polymerase II elongation complex with substrate analogue GMPCPP | x-ray diffraction | H | — | 2 (best 0.89) |
| 1Y77 | Complete RNA polymerase II elongation complex with substrate analogue gmpcpp | x-ray diffraction | H | — | 2 (best 0.89) |
| 2B63 | Complete RNA Polymerase II-RNA inhibitor complex | x-ray diffraction | H | — | — |
| 2B63 | Complete RNA polymerase II-RNA inhibitor complex | x-ray diffraction | H | — | 3 (best 0.89) |
| 2B8K | 12-subunit RNA Polymerase II | x-ray diffraction | H | — | — |
| 2B8K | 12-subunit RNA polymerase II | x-ray diffraction | H | — | 2 (best 0.89) |
| 2E2H | RNA polymerase II elongation complex at 5 mM Mg2+ with GTP | x-ray diffraction | H | — | 2 (best 0.87) |
| 2E2H | RNA polymerase II elongation complex at 5 mm MG2+ with GTP | x-ray diffraction | H | — | 2 (best 0.87) |
| 2E2I | RNA polymerase II elongation complex in 5 mM Mg+2 with 2'-dGTP | x-ray diffraction | H | — | 2 (best 0.89) |
| 2E2I | RNA polymerase II elongation complex in 5 mm MG+2 with 2'- dgtp | x-ray diffraction | H | — | 2 (best 0.89) |
| 2E2J | RNA polymerase II elongation complex in 5 mM Mg+2 with GMPCPP | x-ray diffraction | H | — | 4 (best 0.88) |
| 2E2J | RNA polymerase II elongation complex in 5 mm MG+2 with gmpcpp | x-ray diffraction | H | — | 4 (best 0.88) |
| 2JA5 | CPD lesion containing RNA Polymerase II elongation complex A | x-ray diffraction | H | — | 3 (best 0.89) |
| 2JA5 | Cpd lesion containing RNA polymerase II elongation complex a | x-ray diffraction | H | — | 3 (best 0.89) |
| 2JA6 | CPD lesion containing RNA Polymerase II elongation complex B | x-ray diffraction | H | — | 3 (best 0.89) |
| 2JA6 | Cpd lesion containing RNA polymerase II elongation complex B | x-ray diffraction | H | — | 3 (best 0.89) |
| 2JA7 | CPD lesion containing RNA Polymerase II elongation complex C | x-ray diffraction | H, T | — | 2 (best 0.88) |
| 2JA7 | Cpd lesion containing RNA polymerase II elongation complex C | x-ray diffraction | H, T | — | 2 (best 0.88) |
368 records more on the page itself.
Experiment against prediction
- 6HLQ chain H against the predicted model P20436: TM-score 0.98, RMSD 0.69 Å
- 6HKO chain H against the predicted model P20436: TM-score 0.98, RMSD 0.71 Å
- 4C2M chain H against the predicted model P20436: TM-score 0.97, RMSD 0.76 Å
- 4C3H chain H against the predicted model P20436: TM-score 0.95, RMSD 0.97 Å
- 3CQZ chain H against the predicted model P20436: TM-score 0.95, RMSD 1.06 Å
- 4BBS chain H against the predicted model P20436: TM-score 0.95, RMSD 1.02 Å
- 4BBR chain H against the predicted model P20436: TM-score 0.95, RMSD 1.04 Å
- 3S14 chain H against the predicted model P20436: TM-score 0.94, RMSD 1.07 Å
- 4BY1 chain H against the predicted model P20436: TM-score 0.94, RMSD 1.11 Å
- 4BY1 chain H against the predicted model P20436: TM-score 0.94, RMSD 1.11 Å
Elsewhere
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