RNA polymerase I pre-initiation complex

Structure

electron microscopy · 31 distinct chains · 38% helix, 20% strand (DSSP).

Ligands and binding sites

• ZN · Zinc ion · metal · 7 copies · chains A, B, I, J, L

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.

Interfaces

67 interfaces between chains.

• A–B · 9204 Ų buried · 141 hydrogen bonds · protein-protein
• A–I · 3008 Ų buried · 37 hydrogen bonds · protein-protein
• A–E · 2902 Ų buried · 50 hydrogen bonds · protein-protein
• M–N · 2474 Ų buried · 29 hydrogen bonds · protein-protein
• A–F · 2239 Ų buried · 25 hydrogen bonds · protein-protein

Compared structures

• 5OA1 · RNA polymerase I pre-initiation complex · the same entry in another collection · chain C against C, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P10964
• Every structure of UniProt P22138
• Every structure of UniProt P07703
• Every structure of UniProt P50106
• Every structure of UniProt P20434
• Every structure of UniProt P20435
• Every structure of UniProt P46669
• Every structure of UniProt P20436
• Every structure of UniProt P32529
• Every structure of UniProt P22139
• Every structure of UniProt P28000
• Every structure of UniProt P40422
• Every structure of UniProt Q01080
• Every structure of UniProt P47006
• Every structure of UniProt P36070
• Every structure of UniProt P40992
• Every structure of UniProt P32786
• Every structure of UniProt Q04712
• Elsewhere: RCSB PDB 5OA1 · PDBe 5OA1 · UniProt P10964 · UniProt P22138 · UniProt P07703 · UniProt P50106 · UniProt P20434 · UniProt P20435 · UniProt P46669 · UniProt P20436 · UniProt P32529 · UniProt P22139 · UniProt P28000 · UniProt P40422 · UniProt Q01080 · UniProt P47006 · UniProt P36070 · UniProt P40992 · UniProt P32786 · UniProt Q04712