UniProt P36070
RNA polymerase I-specific transcription initiation factor RRN3 (P36070)
RNA polymerase I-specific transcription initiation factor RRN3 (UniProt P36070): 28 experimental structures and 1 predicted model on GenesisL1, 26 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- P36070
- Protein
- RNA polymerase I-specific transcription initiation factor RRN3
- Experimental structures
- 28
- Predicted models
- 1
- Pockets
- 26 · 11 records with a druggable one
Structures
29 records of P36070 in the MolNFT archive: 28 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3TJ1 | Crystal Structure of RNA Polymerase I Transcription Initiation Factor Rrn3 | x-ray diffraction | A, B | — | — |
| 3TJ1 | Crystal structure of RNA polymerase I transcription initiation factor RRN3 | x-ray diffraction | A, B | — | — |
| 5G5L | RNA polymerase I-RRN3 complex at 4.8 a resolution | electron microscopy | O | — | — |
| 5N5Y | Cryo-EM structure of RNA polymerase I in complex with Rrn3 and Core Factor (Orientation III) | electron microscopy | O | — | 2 (best 0.79) |
| 5N5Y | Cryo-EM structure of RNA polymerase I in complex with RRN3 and core factor (orientation III) | electron microscopy | O | — | — |
| 5N5Z | Cryo-EM structure of RNA polymerase I in complex with Rrn3 and Core Factor (Orientation II) | electron microscopy | O | — | 2 (best 0.82) |
| 5N5Z | Cryo-EM structure of RNA polymerase I in complex with RRN3 and core factor (orientation II) | electron microscopy | O | — | — |
| 5N60 | Cryo-EM structure of RNA polymerase I in complex with Rrn3 and Core Factor (Orientation I) | electron microscopy | O | — | 2 (best 0.80) |
| 5N60 | Cryo-EM structure of RNA polymerase I in complex with RRN3 and core factor (orientation I) | electron microscopy | O | — | — |
| 5N61 | RNA polymerase I initially transcribing complex | electron microscopy | O | — | — |
| 5OA1 | RNA polymerase I pre-initiation complex | electron microscopy | O | — | 1 (best 0.82) |
| 5OA1 | RNA polymerase I pre-initiation complex | electron microscopy | O | — | — |
| 6RQH | RNA Polymerase I Closed Conformation 1 (CC1) | electron microscopy | O | — | — |
| 6RQH | RNA polymerase I closed conformation 1 (CC1) | electron microscopy | O | — | — |
| 6RQL | RNA Polymerase I Closed Conformation 2 (CC2) | electron microscopy | O | — | 1 (best 0.85) |
| 6RQL | RNA polymerase I closed conformation 2 (CC2) | electron microscopy | O | — | — |
| 6RQT | RNA Polymerase I-tWH-Rrn3-DNA | electron microscopy | O | — | — |
| 6RQT | RNA polymerase I-twh-RRN3-DNA | electron microscopy | O | — | — |
| 6RRD | RNA Polymerase I Pre-initiation complex DNA opening intermediate 1 | electron microscopy | O | — | 3 (best 0.85) |
| 6RRD | RNA polymerase I pre-initiation complex DNA opening intermediate 1 | electron microscopy | O | — | — |
| 6RUI | RNA Polymerase I Pre-initiation complex DNA opening intermediate 2 | electron microscopy | O | — | 2 (best 0.83) |
| 6RUI | RNA polymerase I pre-initiation complex DNA opening intermediate 2 | electron microscopy | O | — | — |
| 6RUO | RNA Polymerase I Open Complex conformation 1 | electron microscopy | O | — | 4 (best 0.82) |
| 6RUO | RNA polymerase I open complex conformation 1 | electron microscopy | O | — | — |
| 6RWE | RNA Polymerase I Open Complex conformation 2 | electron microscopy | O | — | 2 (best 0.81) |
| 6RWE | RNA polymerase I open complex conformation 2 | electron microscopy | O | — | — |
| 6TPS | early intermediate RNA Polymerase I Pre-initiation complex - eiPIC | electron microscopy | O | — | 2 (best 0.83) |
| 6TPS | Early intermediate RNA polymerase I pre-initiation complex - eipic | electron microscopy | O | — | — |
| P36070 | AlphaFold monomer V2.0 prediction for RNA polymerase I-specific transcription initiation factor… | predicted | A | — | 5 (best 0.52) |
Experiment against prediction
- 3TJ1 chain B against the predicted model P36070: TM-score 0.98, RMSD 1.19 Å
- 3TJ1 chain B against the predicted model P36070: TM-score 0.98, RMSD 1.19 Å
- 3TJ1 chain A against the predicted model P36070: TM-score 0.98, RMSD 1.20 Å
- 3TJ1 chain A against the predicted model P36070: TM-score 0.98, RMSD 1.20 Å
- 5N61 chain O against the predicted model P36070: TM-score 0.98, RMSD 1.19 Å
- 5N60 chain O against the predicted model P36070: TM-score 0.98, RMSD 1.28 Å
- 5N60 chain O against the predicted model P36070: TM-score 0.98, RMSD 1.28 Å
- 5N5Y chain O against the predicted model P36070: TM-score 0.98, RMSD 1.28 Å
- 5N5Y chain O against the predicted model P36070: TM-score 0.98, RMSD 1.28 Å
- 5N5Z chain O against the predicted model P36070: TM-score 0.98, RMSD 1.28 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.