Ligand · 4QM
4QM · (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol
4QM, (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol (C24 H42 O3, 378.6 g/mol), in the MolNFT structures on GenesisL1…
- Component
- 4QM
- Formula
- C24 H42 O3
- Class
- ligand
- Structures
- 6
- PDB entries
- 6
Binding sites
4QM in 6 structures; the first of them:
- 7Z1L · Structure of yeast RNA Polymerase III Pre-Termination Complex (PTC) · 4QM A2003 · binds LYS1134, ASP1277, TYR1298, HIS1318, LEU1320, GLU1321
- 7Z1M · Structure of yeast RNA Polymerase III Elongation Complex (EC) · 4QM A2003 · binds LYS1134, ASP1277, TYR1298, HIS1318, LEU1320, GLU1321
- 7Z2Z · Structure of yeast RNA Polymerase III-DNA-Ty1 integrase complex (Pol III-DNA-IN1) at 3.1 A · 4QM A1504 · binds LYS1134, VAL1135, ASP1277, TYR1298, HIS1318, LEU1320, GLU1321, SER1324
- 8BWS · Structure of yeast RNA Polymerase III elongation complex at 3.3 A · 4QM A1504 · binds LYS1134, ASP1277, TYR1298, HIS1318, LEU1320, GLU1321, SER1324
- 8EHF · Cryo-EM structure of his-elemental paused elongation complex with an unfolded TL (1) · 4QM I1401 · binds GLN46, TYR47, TYR179, ASP396, SER398, ALA399, VAL400, ARG452 and 5 more
- 8TO1 · Escherichia coli RNA polymerase unwinding intermediate (I1a) at the lambda PR promoter · 4QM I1401 · binds GLU72, ASP135, GLN725, TYR726, ARG731, GLU962, GLN965, ILE966 and 1 more
Residues it binds most
GLU 10, TYR 8, ASP 11, LYS 7, ILE 7, PHE 5, LEU 7, SER 5, GLN 3, HIS 4 (residue and the binding sites it lines).
Found with
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