UniProt P16442
Histo-blood group ABO system transferase (P16442)
Histo-blood group ABO system transferase (UniProt P16442), EC 2.4.1.37, 2.4.1.40: 215 experimental structures and 1 predicted model on GenesisL1, 14 ligands bound, 28 pockets. Binding sites, druggability and experiment against…
- UniProt
- P16442
- Protein
- Histo-blood group ABO system transferase
- EC
- 2.4.1.37, 2.4.1.40
- Experimental structures
- 215
- Predicted models
- 1
- Ligands
- 14
- Pockets
- 28 · 14 records with a druggable one
Structures
216 records of P16442 in the MolNFT archive: 215 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1LZ0 | Glycosyltransferase A | x-ray diffraction | A | — | — |
| 1LZ0 | Glycosyltransferase a | x-ray diffraction | A | — | — |
| 1LZ7 | Glycosyltransferase B | x-ray diffraction | A | — | — |
| 1LZ7 | Glycosyltransferase B | x-ray diffraction | A | — | — |
| 1LZI | Glycosyltransferase A + UDP + H antigen acceptor | x-ray diffraction | A | — | — |
| 1LZI | Glycosyltransferase a + udp + H antigen acceptor | x-ray diffraction | A | — | — |
| 1R7T | Glycosyltransferase A in complex with 3-deoxy-acceptor analog inhibitor | x-ray diffraction | A | — | — |
| 1R7T | Glycosyltransferase a in complex with 3-deoxy-acceptor analog inhibitor | x-ray diffraction | A | — | — |
| 1R7U | Glycosyltransferase B in complex with 3-deoxy-acceptor analog inhibitor | x-ray diffraction | A | — | — |
| 1R7U | Glycosyltransferase B in complex with 3-deoxy-acceptor analog inhibitor | x-ray diffraction | A | — | — |
| 1R7V | Glycosyltransferase A in complex with 3-amino-acceptor analog inhibitor | x-ray diffraction | A | — | — |
| 1R7V | Glycosyltransferase a in complex with 3-amino-acceptor analog inhibitor | x-ray diffraction | A | — | — |
| 1R7X | Glycosyltransferase B in complex with 3-amino-acceptor analog inhibitor | x-ray diffraction | A | — | — |
| 1R7X | Glycosyltransferase B in complex with 3-amino-acceptor analog inhibitor | x-ray diffraction | A | — | — |
| 1R7Y | Glycosyltransferase A in complex with 3-amino-acceptor analog inhibitor and uridine diphosphate | x-ray diffraction | A | — | — |
| 1R7Y | Glycosyltransferase a in complex with 3-amino-acceptor analog inhibitor and uridine diphosphate | x-ray diffraction | A | — | — |
| 1R80 | Glycosyltransferase B in complex with 3-amino-acceptor analog inhibitor and uridine diphosphate | x-ray diffraction | A | — | — |
| 1R80 | Glycosyltransferase B in complex with 3-amino-acceptor analog inhibitor and uridine diphosphate | x-ray diffraction | A | — | — |
| 1R81 | Glycosyltransferase A in complex with 3-amino-acceptor analog inhibitor and uridine… | x-ray diffraction | A | — | — |
| 1R81 | Glycosyltransferase a in complex with 3-amino-acceptor analog inhibitor and uridine… | x-ray diffraction | A | — | — |
| 1R82 | Glycosyltransferase B in complex with 3-amino-acceptor analog inhibitor, and uridine… | x-ray diffraction | A | — | — |
| 1R82 | Glycosyltransferase B in complex with 3-amino-acceptor analog inhibitor, and uridine… | x-ray diffraction | A | — | — |
| 1WSZ | Mutant human ABO(H) blood group transferase A | x-ray diffraction | A | — | — |
| 1WSZ | Mutant human ABO(H) blood group transferase a | x-ray diffraction | A | — | — |
| 1WT0 | Mutant human ABO(H) blood group glycosyltransferase A | x-ray diffraction | A | — | — |
| 1WT0 | Mutant human ABO(H) blood group glycosyltransferase a | x-ray diffraction | A | — | — |
| 1WT1 | Mutant ABO(H) blood group glycosyltransferase with bound UDP and acceptor | x-ray diffraction | A | — | — |
| 1WT1 | Mutant ABO(H) blood group glycosyltransferase with bound udp and acceptor | x-ray diffraction | A | — | — |
| 1WT2 | Mutant human ABO(H) blood group glycosyltransferase A with bound UDP and inhibitor | x-ray diffraction | A | — | — |
| 1WT2 | Mutant human ABO(H) blood group glycosyltransferase a with bound udp and inhibitor | x-ray diffraction | A | — | — |
| 1WT3 | Mutant human ABO(H) blood group glycosyltransferase with bound UDP and acceptor | x-ray diffraction | A | — | — |
| 1WT3 | Mutant human ABO(H) blood group glycosyltransferase with bound udp and acceptor | x-ray diffraction | A | — | — |
| 1XZ6 | Mutant ABO(H) blood group glycosyltransferase A | x-ray diffraction | A | — | — |
| 1XZ6 | Mutant ABO(H) blood group glycosyltransferase a | x-ray diffraction | A | — | — |
| 1ZHJ | Crystal Structure of human N-acetylgalactosaminyltransferase (GTA) Complexed with Galactose | x-ray diffraction | A | — | — |
| 1ZHJ | Crystal structure of human N-acetylgalactosaminyltransferase (gta) complexed with galactose | x-ray diffraction | A | — | — |
| 1ZI1 | Crystal Structure of Human N-acetylgalactosaminyltransferase (GTA) Complexed with Lactose | x-ray diffraction | A | — | — |
| 1ZI1 | Crystal structure of human N-acetylgalactosaminyltransferase (gta) complexed with lactose | x-ray diffraction | A | — | — |
| 1ZI3 | Crystal Structure of Human N-acetylgalactosaminyltransferase (GTA) Complexed with… | x-ray diffraction | A | — | — |
| 1ZI3 | Crystal structure of human N-acetylgalactosaminyltransferase (gta) complexed with… | x-ray diffraction | A | — | — |
| 1ZI4 | Crystal Structure of Human N-acetylgalactosaminyltransferase (GTA) Complexed with H type II… | x-ray diffraction | A | — | — |
| 1ZI4 | Crystal structure of human N-acetylgalactosaminyltransferase (gta) complexed with H type II… | x-ray diffraction | A | — | — |
| 1ZI5 | Crystal Structure of Human N-acetylgalactosaminyltransferase (GTA) Complexed with H type I… | x-ray diffraction | A | — | — |
| 1ZI5 | Crystal structure of human N-acetylgalactosaminyltransferase (gta) complexed with H type I… | x-ray diffraction | A | — | — |
| 1ZIZ | Crystal Structure of Human Galactosyltransferase (GTB) Complexed with Galactose | x-ray diffraction | A | — | — |
| 1ZIZ | Crystal structure of human galactosyltransferase (gtb) complexed with galactose | x-ray diffraction | A | — | — |
| 1ZJ0 | Crystal Structure of Human Galactosyltransferase (GTB) Complexed with Lactose | x-ray diffraction | A | — | — |
| 1ZJ0 | Crystal structure of human galactosyltransferase (gtb) complexed with lactose | x-ray diffraction | A | — | — |
| 1ZJ1 | Crystal Structure of Human Galactosyltransferase (GTB) Complexed with N-acetyllactosamine | x-ray diffraction | A | — | — |
| 1ZJ1 | Crystal structure of human galactosyltransferase (gtb) complexed with N-acetyllactosamine | x-ray diffraction | A | — | — |
| 1ZJ2 | Crystal Structure of Human Galactosyltransferase (GTB) Complexed with H type I Trisaccharide | x-ray diffraction | A | — | — |
| 1ZJ2 | Crystal structure of human galactosyltransferase (gtb) complexed with H type I trisaccharide | x-ray diffraction | A | — | — |
| 1ZJ3 | Crystal Structure of Human Galactosyltransferase (GTB) Complexed with H type II Trisaccharide | x-ray diffraction | A | — | — |
| 1ZJ3 | Crystal structure of human galactosyltransferase (gtb) complexed with H type II trisaccharide | x-ray diffraction | A | — | — |
| 1ZJO | Crystal Structure of Human N-acetylgalactosaminyltransferase (GTA) Complexed with Galactose-grease | x-ray diffraction | A | — | — |
| 1ZJO | Crystal structure of human N-acetylgalactosaminyltransferase (gta) complexed with galactose-grease | x-ray diffraction | A | — | — |
| 1ZJP | Crystal Structure of Human Galactosyltransferase (GTB) Complexed with Galactose-grease | x-ray diffraction | A | — | — |
| 1ZJP | Crystal structure of human galactosyltransferase (gtb) complexed with galactose-grease | x-ray diffraction | A | — | — |
| 2A8U | Crystal Structure of Human Galactosyltransferase (GTB) Complexed with Beta-Methyl Lactoside | x-ray diffraction | A | — | — |
| 2A8U | Crystal structure of human galactosyltransferase (gtb) complexed with beta-methyl lactoside | x-ray diffraction | A | — | — |
156 records more on the page itself.
Ligands
- MN · Manganese (II) ion · in 17 records
- HG · Mercury (II) ion · in 9 records
- SO4 · Sulfate ion · in 9 records
- DA8 · octyl 3-deoxy-2-O-(6-deoxy-alpha-L-galactopyranosyl)-beta-D-xylo-hexopyranoside · in 6 records
- FUC · alpha-L-fucopyranose · in 5 records
- HSH · octyl beta-D-galactopyranoside · in 5 records
- UDP · Uridine-5'-diphosphate · in 5 records
- U5P · Uridine-5'-monophosphate · in 4 records
- URM · (((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)methyl)phosphonic (((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphoric) anhydride · in 4 records
- GDU · Galactose-uridine-5'-diphosphate · in 3 records
- GLA · alpha-D-galactopyranose · in 3 records
- A2G · 2-acetamido-2-deoxy-alpha-D-galactopyranose · in 2 records
- 4YA · hexyl 2-O-(6-deoxy-alpha-L-galactopyranosyl)-beta-D-galactopyranoside · in 1 record
- UPG · Uridine-5'-diphosphate-glucose · in 1 record
Experiment against prediction
- 4Y63 chain A against the predicted model P16442: TM-score 1.00, RMSD 0.19 Å
- 4Y63 chain A against the predicted model P16442: TM-score 1.00, RMSD 0.19 Å
- 5M7B chain A against the predicted model P16442: TM-score 1.00, RMSD 0.29 Å
- 5M7B chain A against the predicted model P16442: TM-score 1.00, RMSD 0.29 Å
- 5M79 chain A against the predicted model P16442: TM-score 1.00, RMSD 0.30 Å
- 5M79 chain A against the predicted model P16442: TM-score 1.00, RMSD 0.30 Å
- 5M7A chain A against the predicted model P16442: TM-score 1.00, RMSD 0.30 Å
- 5M7A chain A against the predicted model P16442: TM-score 1.00, RMSD 0.30 Å
- 3ZGF chain B against the predicted model P16442: TM-score 1.00, RMSD 0.29 Å
- 3ZGF chain B against the predicted model P16442: TM-score 1.00, RMSD 0.29 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.