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Ligand · GAL

GAL · beta-D-galactopyranose

GAL, beta-D-galactopyranose (C6 H12 O6, 180.2 g/mol), in the MolNFT structures on GenesisL1: bound in 788 records (574 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with…

Component
GAL
Formula
C6 H12 O6
Class
sugar
Structures
788
PDB entries
574

Binding sites

GAL in 788 structures; the first of them:

  • 4WZL · Crystal structure of P domain from norovirus strain Saga4 in complex with HBGA type Lea… · GAL C2 · binds GLY392, TYR444
  • 4X10 · JC Polyomavirus genotype 3 VP1 in complex with GM2 oligosaccharide · GAL F2
  • 4X15 · JC Mad-1 polyomavirus VP1 in complex with GM2 oligosaccharide · GAL F2
  • 4XBL · Crystal Structure of Human Galectin-1 in Complex with Type 1 N-acetyllactosamine · GAL C2 · binds HIS44, ASN46, ARG48, HIS52, VAL59, ASN61, TRP68, GLU71
  • 4Y1X · Complex of human Galectin-1 and Galbeta1-4(6OSO3)GlcNAc · GAL C2 · binds HIS44, ASN46, ARG48, HIS52, ASN61, TRP68, GLU71
  • 4Z3G · Crystal structure of the lectin domain of PapG from E. coli BI47 in complex with… · GAL C1 · binds GLU59, GLY104, LYS106, TRP107, ARG170
  • 4ZBV · Structural studies on a non-toxic homologue of type II RIPs from Momordica charantia… · GAL B309 · binds ASP22, VAL23, TYR24, GLY25, ALA26, ILE35, TYR37, GLN42 and 3 more
  • 4ZFW · Structural studies on a non-toxic homologue of type II RIPs from Momordica charantia… · GAL B302 · binds ASP22, VAL23, TYR24, GLY25, TYR37, GLN42, ASN44, ARG112
  • 4ZLB · Structural studies on a non-toxic homologue of type II RIPs from Momordica charantia… · GAL F2 · binds ASP22, VAL23, TYR24, GLY25, ALA26, ILE35, TYR37, GLN42 and 2 more
  • 5A57 · The structure of GH101 from Streptococcus pneumoniae TIGR4 in complex with PUGT · GAL A2457 · binds MET616, PHE618, HIS657, ASP658, TRP724, TRP726, TRP867, GLN868 and 2 more
  • 5A5A · The structure of GH101 E796Q mutant from Streptococcus pneumoniae TIGR4 in complex with… · GAL B2 · binds MET616, PHE618, HIS657, ASP658, TRP724, TRP726, TRP867, GLN868 and 1 more
  • 5BN6 · Crystal Structure of Frutalin from Artocarpus incisa in complex with galactose · GAL E200 · binds GLY25, PHE71, TYR102, VAL104, GLY145, TYR146, TRP147, ASP149
  • 5BNN · Crystal structure of human enterovirus D68 in complex with 6'SL · GAL E2 · binds ALA273, PRO274, GLY282, ASP91
  • 5BNO · Crystal structure of human enterovirus D68 in complex with 6'SLN · GAL E2 · binds PRO274, GLY282, ASP91
  • 5BQZ · Crystal structure of hemagglutinin of A/Chicken/Guangdong/S1311/2010 (H6N6) in complex… · GAL G1
  • 5CA3 · Crystal structure of the glycosynthase mutant D324N of Escherichia coli GH63 glycosidase… · GAL C2 · binds TRP321, ASP368, LEU369, ASN386, LYS391, TRP496, ASP501
  • 5CB7 · Crystallographic structure of human rotavirus K8 VP8* in complex with A-type HBGA · GAL B305 · binds SER187, TYR188, TYR189
  • 5CJZ · BT4246 with galactose · GAL A707 · binds TYR66, LEU67, TRP83, ASP86, TYR371, ARG467, ASP468
  • 5CPW · Crystal structure of murine polyomavirus PTA strain VP1 in complex with the GT1a glycan · GAL F1

Residues it binds most

ASN 713, ASP 699, GLU 784, TRP 661, TYR 519, HIS 627, GLY 482, ARG 506, LYS 498, GLN 375 (residue and the binding sites it lines).

Found with

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • BMA · beta-D-mannopyranose
  • FUC · alpha-L-fucopyranose
  • SIA · N-acetyl-alpha-neuraminic acid
  • MAN · alpha-D-mannopyranose
  • BGC · beta-D-glucopyranose
  • CA · Calcium ion
  • GOL · Glycerol
  • EDO · 1,2-ethanediol
  • GLC · alpha-D-glucopyranose
  • CL · Chloride ion
  • NA · Sodium ion

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