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Ligand · UD2

UD2 · Uridine-diphosphate-N-acetylgalactosamine

UD2, Uridine-diphosphate-N-acetylgalactosamine (C17 H27 N3 O17 P2, 607.4 g/mol), in the MolNFT structures on GenesisL1: bound in 15 records (13 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and…

Component
UD2
Formula
C17 H27 N3 O17 P2
Class
ligand
Structures
15
PDB entries
13

Binding sites

UD2 in 15 structures; the first of them:

  • 6D99 · Crystal structure of Corynebacterium diphtheriae UDP-galactopyranose mutase in complex… · UD2 A403 · binds HIS64, PHE98, PHE153, ILE154, TYR157, THR158, GLN161, TRP162 and 8 more
  • 6GX1 · Blood group synthase AAGlyB in complex with UDP-GalNAc and cryoprotected with PEG 3350 · UD2 A402 · binds PHE121, ALA122, ILE123, LYS124, TYR126, TRP181, VAL184, SER185 and 5 more
  • 7YSM · Crystal Structure of UDP-glucose 4-epimerase (Rv3634c) co-crystallized with… · UD2 A402 · binds ILE81, VAL83, ARG84, SER121, GLY123, SER124, TYR146, PRO173 and 19 more
  • 7YSY · Crystal Structure of UDP-glucose 4-epimerase (Rv3634c) co-crystallized with… · UD2 A402 · binds ILE81, VAL83, ARG84, SER121, GLY123, SER124, TYR146, PRO173 and 17 more
  • 8B63 · Crystal Structure of P. aeruginosa WaaG in complex with UDP-GalNAc · UD2 A401 · binds PRO12, PHE13, GLY14, GLY15, LEU16, ARG18, ASP19, TYR97 and 21 more
  • 8DQD · Structure of the Campylobacter concisus glycosyltransferase PglA · UD2 A401 · binds MET12, PHE16, PHE17, GLU113, GLY114, VAL150, VAL175, ILE201 and 15 more
  • 8JJQ · Structure of SenB in complex with UDP-GalNAc at 1.64 Angstroms resolution · UD2 C401 · binds ASN17, ASN18, GLY19, ASN20, ARG22, THR23, LEU57, THR83 and 25 more
  • 6D99 · Crystal structure of corynebacterium diphtheriae udp-galactopyranose mutase in complex… · UD2 A403 · binds HIS64, PHE98, PHE153, ILE154, TYR157, THR158, GLN161, TRP162 and 7 more
  • 6D9A · Crystal structure of corynebacterium diphtheriae udp-galactopyranose mutase in complex… · UD2 A403 · binds PHE98, PHE153, ILE154, TYR157, THR158, GLN161, TRP162, TYR187 and 5 more
  • 6EGS · Crystal structure of the galnac-T2 F104S mutant in complex with udp- galnac · UD2 A602 · binds THR143, PHE144, HIS145, ASP176, ARG201, GLY203, LEU204, SER207 and 13 more
  • 6EJI · Structure of a glycosyltransferase · UD2 A401 · binds SER14, GLY16, ALA17, ARG19, PHE45, TYR46, HIS118, SER119 and 20 more
  • 6GX1 · Blood group synthase aaglyb in complex with udp-galnac and cryoprotected with peg 3350 · UD2 A402 · binds PHE121, ALA122, ILE123, LYS124, TYR126, TRP181, VAL184, SER185 and 5 more
  • 6IWR · Crystal structure of galnac-T7 with udp, galnac and MN2+ · UD2 D704 · binds LYS163, GLN167, GLY457, SER458, SER459, ASP547, MET549, HIS563 and 5 more
  • 6SVM · Crystal structure of human gfat-1 in complex with glucose-6-phosphate, L-glu, and… · UD2 A703 · binds GLN310, ARG343, GLY354, GLY355, GLY445, THR447, VAL450, SER455 and 5 more
  • 6WJA · Udp-glcnac C4-epimerase mutant S121A/Y146F from pseudomonas protegens in complex with… · UD2 A402 · binds VAL83, ALA123, ASN175, TYR187, SER188, GLY189, VAL190, PHE194 and 9 more

Residues it binds most

GLY 18, ARG 22, VAL 19, ASN 17, PHE 17, THR 16, TYR 13, ILE 18, SER 16, LEU 12 (residue and the binding sites it lines).

Found with

  • UDP · Uridine-5'-diphosphate
  • MN · Manganese (II) ion
  • NA · Sodium ion
  • NAD · Nicotinamide-adenine-dinucleotide
  • IPA · Isopropyl alcohol
  • FAD · Flavin-adenine dinucleotide
  • SO4 · Sulfate ion
  • ACT · Acetate ion
  • PEG · Di(hydroxyethyl)ether
  • FDA · Dihydroflavine-adenine dinucleotide
  • G6Q · Glucose-6-phosphate
  • K · Potassium ion

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