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Ligand · FAD

FAD · Flavin-adenine dinucleotide

FAD, Flavin-adenine dinucleotide (C27 H33 N9 O15 P2, 785.5 g/mol), in the MolNFT structures on GenesisL1: bound in 1,680 records (1,169 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
FAD
Formula
C27 H33 N9 O15 P2
Class
ligand
Structures
1,680
PDB entries
1,169

Binding sites

FAD in 1,680 structures; the first of them:

  • 4XBF · Structure of LSD1:CoREST in complex with ssRNA · FAD A901 · binds ILE284, GLY285, SER286, GLY287, VAL288, SER289, GLY290, LEU307 and 33 more
  • 4XWR · X-ray structure of perdeuterated Cholesterol Oxidase from Streptomyces SA-COO · FAD A601 · binds ILE16, GLY17, THR18, GLY19, TYR20, GLY21, LEU39, GLU40 and 34 more
  • 4YAF · rat CYPOR with 2'-AMP · FAD A702 · binds HIS319, THR378, ARG424, ARG454, TYR455, TYR456, SER457, CYS472 and 13 more
  • 4YAO · Reduced CYPOR mutant - G143del · FAD A702 · binds HIS319, THR378, ARG424, ARG454, TYR455, TYR456, SER457, CYS472 and 12 more
  • 4YAU · Reduced CYPOR mutant - G141del/E142N · FAD A702 · binds HIS319, THR378, ARG424, ARG454, TYR455, TYR456, SER457, CYS472 and 13 more
  • 4YJG · Crystal structure of DAAO(Y228L/R283G) variant (R-3-amino 1-phenylbutane binding form) · FAD A402 · binds ILE6, GLY7, ALA8, GLY9, VAL10, ILE11, GLY12, TYR35 and 33 more
  • 4YNU · Crystal structure of Aspergillus flavus FADGDH in complex with D-glucono-1,5-lactone · FAD A601 · binds GLY12, GLY13, GLY14, THR15, SER16, LEU35, GLU36, ALA37 and 36 more
  • 4Z44 · F454K Mutant of Tryptophan 7-halogenase PrnA · FAD A601 · binds VAL11, GLY12, GLY13, GLY14, THR15, ALA16, ILE37, GLU38 and 32 more
  • 4ZCC · Renalase in complex with NADH · FAD A401 · binds ILE8, GLY9, THR10, GLY11, ILE12, ALA13, GLY14, PHE31 and 31 more
  • 4ZVN · Reduced qui reductase 2 in complex with acridine orange · FAD A302 · binds HIS11, LYS15, SER16, PHE17, ASN18, SER20, PRO102, LEU103 and 18 more
  • 5ADZ · Ether Lipid-Generating Enzyme AGPS in complex with inhibitor 1a · FAD A999 · binds TRP96, HIS189, ILE233, PRO234, ILE235, GLY236, GLY237, GLY238 and 29 more
  • 5AF7 · 3-Sulfinopropionyl-coenzyme A (3SP-CoA) desulfinase from Advenella mimigardefordensis… · FAD A410 · binds ARG84, ILE121, CYS122, ILE123, SER124, GLY129, SER130, TYR153 and 26 more
  • 5AHS · 3-Sulfinopropionyl-Coenzyme A (3SP-CoA) desulfinase from Advenella mimgardefordensis… · FAD A410 · binds ARG84, ILE121, CYS122, ILE123, SER124, GLY129, SER130, TYR153 and 27 more
  • 5BRT · Crystal Structure of 2-hydroxybiphenyl 3-monooxygenase from Pseudomonas azelaica with… · FAD A601 · binds VAL12, GLY13, ALA14, GLY15, PRO16, ALA17, GLY18, ILE35 and 24 more
  • 5BUC · Oxidized qui reductase 2 in complex with ethidium · FAD A302 · binds HIS11, LYS15, SER16, PHE17, ASN18, SER20, PRO102, LEU103 and 17 more
  • 5BUL · Structure of flavin-dependent brominase Bmp2 triple mutant Y302S F306V A345W · FAD A501 · binds ILE12, GLY13, SER14, GLY15, PRO16, ALA17, GLY18, ILE35 and 35 more
  • 5C2T · Crystal structure of Mitochondrial rhodoquinol-fumarate reductase from Ascaris suum with… · FAD A702 · binds ILE47, GLY48, ALA49, GLY50, GLY51, ALA52, VAL70, THR71 and 33 more
  • 5CHO · Crystal Structure of BorF, the Flavin Reductase Component of a Bacterial Two-Component… · FAD A201 · binds VAL48, HIS59, MET61, THR62, ALA63, ASN64, SER65, CYS79 and 19 more

Residues it binds most

GLY 3628, ALA 3308, THR 3251, LEU 3357, VAL 3253, SER 3249, ILE 2981, ARG 3261, TYR 2830, ASP 2621 (residue and the binding sites it lines).

Found with

  • GOL · Glycerol
  • SO4 · Sulfate ion
  • MG · Magnesium ion
  • CL · Chloride ion
  • PEG · Di(hydroxyethyl)ether
  • NAP · Nadp nicotinamide-adenine-dinucleotide phosphate
  • FES · Fe2/s2 (inorganic) cluster
  • SF4 · Iron/sulfur cluster
  • PGE · Triethylene glycol
  • EDO · 1,2-ethanediol
  • FMN · Flavin mononucleotide
  • NA · Sodium ion

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