UniProt P02866
concanavalin A (P02866)
concanavalin A (UniProt P02866): 138 experimental structures and 1 predicted model on GenesisL1, 30 ligands bound, 127 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P02866
- Protein
- concanavalin A
- Experimental structures
- 138
- Predicted models
- 1
- Ligands
- 30
- Pockets
- 127 · 26 records with a druggable one
Structures
139 records of P02866 in the MolNFT archive: 138 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1APN | The crystallographic structure of metal-free concanavalin a at 2.5 ångströms resolution | x-ray diffraction | A, B | — | 2 (best 0.70) |
| 1APN | The crystallographic structure of metal-free concanavalin a at 2.5 ångströms resolution | x-ray diffraction | A, B | — | — |
| 1BXH | Concanavalin a complexed to methyl ALPHA1-2 mannobioside | x-ray diffraction | A, B, C, D | MMA, AMG, MN, CA | 6 (best 0.88) |
| 1BXH | Concanavalin a complexed to methyl ALPHA1-2 mannobioside | x-ray diffraction | A, B, C, D | — | — |
| 1CES | Crystals of demetallized concanavalin a soaked with zinc have a zinc ion bound in the S1 site | x-ray diffraction | A, B | ZN | 2 (best 0.71) |
| 1CES | Crystals of demetallized concanavalin a soaked with zinc have a zinc ion bound in the S1 site | x-ray diffraction | A, B | — | — |
| 1CJP | Concanavalin a complex with 4'-methylumbelliferyl-alpha-D-glucopyranoside | x-ray diffraction | A, B, C, D | MUG, MN, CA | 4 (best 0.84) |
| 1CJP | Concanavalin a complex with 4'-methylumbelliferyl-alpha-D- glucopyranoside | x-ray diffraction | A, B, C, D | — | — |
| 1CN1 | Crystal structure of demetallized concanavalin a. the metal-binding region | x-ray diffraction | A, B | — | 2 (best 0.73) |
| 1CN1 | Crystal structure of demetallized concanavalin a. the metal- binding region | x-ray diffraction | A, B | — | — |
| 1CON | The refined structure of cadmium substituted concanavalin a at 2.0 ångströms resolution | x-ray diffraction | A | CD, CA | — |
| 1CON | The refined structure of cadmium substituted concanavalin a at 2.0 ångströms resolution | x-ray diffraction | A | — | — |
| 1CVN | Concanavalin a complexed to trimannoside | x-ray diffraction | A, B, C, D | MAN, MN, CA | 6 (best 0.88) |
| 1CVN | Concanavalin a complexed to trimannoside | x-ray diffraction | A, B, C, D | — | — |
| 1DQ6 | Manganese;Manganese concanavalin A at pH 7.0 | x-ray diffraction | A | MN | — |
| 1DQ6 | MANGANESE;MANGANESE concanavalin a at pH 7.0 | x-ray diffraction | A | — | — |
| 1ENQ | Co-crystals of demetallized concanavalin a with zinc having a zinc ion bound in the S1 site | x-ray diffraction | A, B, C, D | ZN | 4 (best 0.76) |
| 1ENQ | Co-crystals of demetallized concanavalin a with zinc having a zinc ion bound in the S1 site | x-ray diffraction | A, B, C, D | — | — |
| 1ENR | Co-crystals of demetallized concanavalin a with zinc and calcium having a zinc ion bound in the S1… | x-ray diffraction | A | CA, ZN | — |
| 1ENR | Co-crystals of demetallized concanavalin a with zinc and calcium having a zinc ion bound in the S1… | x-ray diffraction | A | — | — |
| 1ENS | Crystals of demetallized concanavalin a soaked with cobalt having a cobalt ion bound in the S1 site | x-ray diffraction | A, B | CO | 1 (best 0.33) |
| 1ENS | Crystals of demetallized concanavalin a soaked with cobalt having a cobalt ion bound in the S1 site | x-ray diffraction | A, B | — | — |
| 1GIC | Concanavalin a complexed with methyl alpha-D-glucopyranoside | x-ray diffraction | A, B | GYP, MN, CA | — |
| 1GIC | Concanavalin a complexed with methyl alpha-D-glucopyranoside | x-ray diffraction | A, B | — | — |
| 1GKB | Concanavalin a, new crystal form | x-ray diffraction | A, B | MN, CA, MG | — |
| 1GKB | Concanavalin a, new crystal form | x-ray diffraction | A, B | — | — |
| 1I3H | Concanavalin a-dimannose structure | x-ray diffraction | A | MAN, MN, CA | — |
| 1I3H | Concanavalin a-dimannose structure | x-ray diffraction | A | — | — |
| 1JBC | Concanavalin a | x-ray diffraction | A | MN, CA | — |
| 1JBC | Concanavalin a | x-ray diffraction | A | — | — |
| 1JN2 | Crystal Structure of meso-tetrasulphonatophenyl porphyrin complexed with Concanavalin A | x-ray diffraction | P | CA, MN, SFP | — |
| 1JN2 | Crystal structure of meso-tetrasulphonatophenyl porphyrin complexed with concanavalin a | x-ray diffraction | P | — | — |
| 1JW6 | Crystal Structure of the Complex of Concanavalin A and Hexapeptide | x-ray diffraction | A | MN, CA, PTD | — |
| 1JW6 | Crystal structure of the complex of concanavalin a and hexapeptide | x-ray diffraction | A | — | — |
| 1NLS | Concanavalin a and its bound solvent at 0.94A resolution | x-ray diffraction | A | MN, CA | — |
| 1NLS | Concanavalin a and its bound solvent at 0.94A resolution | x-ray diffraction | A | — | — |
| 1NXD | Crystal structure of MnMn Concanavalin A | x-ray diffraction | 1, 2, 3, 4 | AZI, MN, NA | 2 (best 0.60) |
| 1NXD | Crystal structure of mnmn concanavalin a | x-ray diffraction | 1, 2, 3, 4 | — | — |
| 1ONA | Co-crystals of concanavalin a with methyl-3,6-di-O-(alpha-D-mannopyranosyl)-alpha-D-mannopyranoside | x-ray diffraction | A, B, C, D | MMA, MAN, MN, CA | 3 (best 0.86) |
| 1ONA | Co-crystals of concanavalin a with methyl-3,6-di-O-(alpha-D- mannopyranosyl)-alpha-D-mannopyranoside | x-ray diffraction | A, B, C, D | — | — |
| 1QNY | X-ray refinement of D2O soaked crystal of concanavalin A | x-ray diffraction | A | MN, CA | — |
| 1QNY | X-ray refinement of D2O soaked crystal of concanavalin a | x-ray diffraction | A | — | — |
| 1SCR | High-resolution structures of single-metal-substituted concanavalin a: the CO,CA-protein at 1.6… | x-ray diffraction | A | NI, CA | — |
| 1SCR | High-resolution structures of single-metal-substituted concanavalin a: the CO,CA-protein at 1.6… | x-ray diffraction | A | — | — |
| 1SCS | High-resolution structures of single-metal-substituted concanavalin a: the CO,CA-protein at 1.6… | x-ray diffraction | A | CO, CA | — |
| 1SCS | High-resolution structures of single-metal-substituted concanavalin a: the CO,CA-protein at 1.6… | x-ray diffraction | A | — | — |
| 1TEI | Structure of concanavalin a complexed to beta-D-glcnac… | x-ray diffraction | A, B, C, D, E, F, G, H | MAN, NAG, MN, CA | 10 (best 0.89) |
| 1TEI | Structure of concanavalin a complexed to beta-D-glcnac (1,2)ALPHA-D… | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 1VAL | Concanavalin a complex with 4'-nitrophenyl-alpha-D-glucopyranoside | x-ray diffraction | A, B, C, D | PNG, MN, CA | 8 (best 0.82) |
| 1VAL | Concanavalin a complex with 4'-nitrophenyl-alpha-D-glucopyranoside | x-ray diffraction | A, B, C, D | — | — |
| 1VAM | Concanavalin a complex with 4'-nitrophenyl-alpha-D-mannopyranoside | x-ray diffraction | A, B, C, D | PNA, MN, CA | 8 (best 0.81) |
| 1VAM | Concanavalin a complex with 4'-nitrophenyl-alpha-D-mannopyranoside | x-ray diffraction | A, B, C, D | — | — |
| 1XQN | The 15k neutron structure of saccharide-free concanavalin A | neutron diffraction | A | MN, CA | — |
| 1XQN | The 15K neutron structure of saccharide-free concanavalin a | neutron diffraction | A | — | — |
| 2CNA | The covalent and three-dimensional structure of concanavalin a, IV.ATOMIC COORDINATES,HYDROGEN… | x-ray diffraction | A | MN, CA | 1 (best 0.51) |
| 2CNA | The covalent and three-dimensional structure of concanavalin a, IV.ATOMIC COORDINATES,HYDROGEN… | x-ray diffraction | A | — | — |
| 2CTV | High resolution crystallographic studies of native concanavalin a using rapid laue data collection… | x-ray diffraction | A | MN, CA | — |
| 2CTV | High resolution crystallographic studies of native concanavalin a using rapid laue data collection… | x-ray diffraction | A | — | — |
| 2ENR | Co-crystals of demetallized concanavalin a with cadmium having a cadmium ion bound in both the S1… | x-ray diffraction | A | CD | — |
| 2ENR | Co-crystals of demetallized concanavalin a with cadmium having a cadmium ion bound in both the S1… | x-ray diffraction | A | — | — |
79 records more on the page itself.
Ligands
- CA · Calcium ion · in 79 records
- MN · Manganese (II) ion · in 74 records
- MAN · alpha-D-mannopyranose · in 24 records
- SQ0 · 3-{[2-(2-hydroxyethoxy)ethyl]amino}-4-[(6-hydroxyhexyl)amino]cyclobut-3-ene-1,2-dione · in 12 records
- MMA · methyl alpha-D-mannopyranoside · in 9 records
- ZN · Zinc ion · in 6 records
- CL · Chloride ion · in 5 records
- CD · Cadmium ion · in 4 records
- NA · Sodium ion · in 3 records
- 2KO · 2-{2-[2-(2-{4-[(alpha-D-mannopyranosyloxy)methyl]-1H-1, 2,3-triazol-1-yl}ethoxy)ethoxy]ethoxy}ethyl 2-[3,6-bis(diethylamino)-9H-xanthen-9-yl]benzoate · in 2 records
- 96O · (1-methyl-1H-1,2,3-triazol-4-yl)methyl alpha-D-mannopyranoside · in 2 records
- A1EAW · ~{N}2,~{N}9-bis[2-[2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyethoxy]ethyl]-1,10-phenanthroline-2,9-dicarboxamide · in 2 records
- CO · Cobalt (II) ion · in 2 records
- ETA · Ethanolamine · in 2 records
- R3M · 2-[2-(2-{4-[(alpha-D-mannopyranosyloxy)methyl]-1H-1,2, 3-triazol-1-yl}ethoxy)ethoxy]ethyl 2-[3,6-bis(diethylamino)-9H-xanthen-9-yl]benzoate · in 2 records
- A1EAT · ~{N}-[2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyethyl]-4-[3-[4-[2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyethylcarbamoyl]phenyl]imidazol-3-ium-1-yl]benzamide · in 1 record
- A1EAU · ~{N}2,~{N}6-bis[2-[2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyethoxy]ethyl]naphthalene-2,6-dicarboxamide · in 1 record
- AMG · methyl alpha-D-galactopyranoside · in 1 record
- AZI · Azide ion · in 1 record
- GYP · methyl alpha-D-glucopyranoside · in 1 record
- MG · Magnesium ion · in 1 record
- MUG · 4-methylumbelliferyl-alpha-D-glucose · in 1 record
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 1 record
- NI · Nickel (II) ion · in 1 record
- PNA · 4-nitrophenyl alpha-D-mannopyranoside · in 1 record
- PNG · 4-nitrophenyl alpha-D-glucopyranoside · in 1 record
- PTD · Pentanedial · in 1 record
- SFP · 5,10,15,20-tetrakis(4-sulpfonatophenyl)-21H,23H-porphine · in 1 record
- WRW · 4-[3,5-bis(4-carboxyphenyl)phenyl]benzoic acid · in 1 record
- WU0 · 4-[3-(4-carboxyphenyl)phenyl]benzoic acid · in 1 record
Experiment against prediction
- 6XT6 chain A against the predicted model P02866: TM-score 1.00, RMSD 0.26 Å
- 6XT6 chain A against the predicted model P02866: TM-score 1.00, RMSD 0.26 Å
- 6XT6 chain B against the predicted model P02866: TM-score 0.97, RMSD 1.29 Å
- 6XT6 chain B against the predicted model P02866: TM-score 0.97, RMSD 1.29 Å
- 5Z5P chain A against the predicted model P02866: TM-score 0.53, RMSD 2.15 Å
- 5Z5P chain A against the predicted model P02866: TM-score 0.53, RMSD 2.15 Å
- 5Z5P chain B against the predicted model P02866: TM-score 0.53, RMSD 2.06 Å
- 5Z5P chain B against the predicted model P02866: TM-score 0.53, RMSD 2.06 Å
- 7MGD chain A against the predicted model P02866: TM-score 0.52, RMSD 2.03 Å
- 7MGD chain A against the predicted model P02866: TM-score 0.52, RMSD 2.03 Å
Elsewhere
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