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Ligand · MMA

MMA · methyl alpha-D-mannopyranoside

MMA, methyl alpha-D-mannopyranoside (C7 H14 O6, 194.2 g/mol), in the MolNFT structures on GenesisL1: bound in 35 records (26 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found…

Component
MMA
Formula
C7 H14 O6
Class
sugar
Structures
35
PDB entries
26

Binding sites

MMA in 35 structures; the first of them:

  • 5AV7 · Crystal structure of Calsepa lectin in complex with bisected glycan · MMA E1 · binds ASN96, TYR141, TYR141
  • 5CNA · Refined structure of concanavalin a complexed with alpha-methyl-D-mannopyranoside at 2.0… · MMA A238 · binds TYR12, ASN14, GLY98, LEU99, TYR100, ALA207, ASP208, THR226 and 2 more
  • 5EYX · Monoclinic Form of Centrolobium tomentosum seed lectin (CTL) complexed with Man1-3Man-OMe. · MMA C1 · binds PHE132, SER137, GLU221, GLN222
  • 5EYY · Tetragonal Form of Centrolobium tomentosum seed lectin (CTL) complexed with Man1-3Man-OMe. · MMA B1 · binds PHE133, ASN137, SER138, GLU222
  • 5F5Q · Crystal structure of Canavalia virosa lectin in complex with alpha-methyl-mannoside · MMA A303 · binds TYR12, ASN14, GLY98, LEU99, TYR100, ALA207, ASP208, GLY227 and 1 more
  • 5JCQ · Crystal structure of the FimH lectin domain from E.coli K12 in complex with methyl… · MMA A301 · binds PHE1, ILE13, ASN46, ASP47, TYR48, ILE52, ASP54, GLN133 and 3 more
  • 5JCR · Crystal structure of the FimH lectin domain from E.coli K12 in complex with methyl… · MMA A301 · binds PHE1, ILE13, ASN46, ASP47, TYR48, ILE52, ASP54, GLN133 and 3 more
  • 5U3E · Crystal Structure of Native Lectin from Canavalia bonariensis Seeds (CaBo) complexed with… · MMA A301 · binds TYR12, ASN14, THR97, GLY98, LEU99, TYR100, ASN168, ALA207 and 4 more
  • 6FWG · Structure of an E333Q variant of the GH99 endo-alpha-mannanase from Bacteroides… · MMA B1 · binds TYR195, ASP196, TYR198, LEU229, PHE253, PHE258, THR259
  • 6GTZ · Crystal structure of a FimH*DsG complex from E.coli F18 with bound dimannoside… · MMA E1 · binds TYR48, ILE52, ASN138
  • 6GU0 · Crystal structure of a FimH*DsG complex from E.coli F18 with bound dimannoside… · MMA C1 · binds ILE13, TYR48, ILE52, TYR137, ASN138
  • 7JUB · C-type carbohydrate-recognition domain 4 of the mannose receptor complexed with… · MMA A802 · binds GLU725, ASN727, TYR729, GLU733, ASN747, ASP748, ILE749
  • 7JUD · C-type carbohydrate-recognition domain 4 of the mannose receptor complexed with… · MMA A803 · binds GLU725, ASN727, TYR729, GLU733, ASN747, ASP748, ILE749
  • 7MGB · Concanavalin A bound to a DNA glycoconjugate, A(Man-T)AT · MMA A301 · binds TYR12, ASN14, GLY98, LEU99, TYR100, ALA207, ASP208, THR226 and 2 more
  • 7MGC · Concanavalin A bound to a DNA glycoconjugate, G(Man-T)AC · MMA A301 · binds TYR12, ASN14, THR97, GLY98, LEU99, TYR100, ALA207, ASP208 and 3 more
  • 7MGD · Concanavalin A bound to a DNA glycoconjugate, T(Man-T)TT · MMA A303 · binds TYR12, ASN14, GLY98, LEU99, TYR100, ALA207, ASP208, GLY227 and 1 more
  • 8ROV · Human dectin-2 with dimerization domain · MMA A403 · binds GLU168, ASN170, GLU174, TRP182, ASN190, ASP191, VAL192
  • 8SZO · Canavalia villosa lectin in complex with alpha-methyl-mannoside · MMA A303 · binds TYR12, ASN14, GLY98, LEU99, TYR100, ALA207, ASP208, THR226 and 2 more
  • 9C4I · Centrolobium microchaete seed lectin (CML) complexed with Man1-3Man-OMe · MMA C1 · binds PHE133, SER138, GLU222, GLN223

Residues it binds most

TYR 63, GLY 38, ASN 62, ASP 57, ALA 36, LEU 37, ARG 32, ILE 23, GLU 18, PHE 13 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion
  • MN · Manganese (II) ion
  • MAN · alpha-D-mannopyranose
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • SO4 · Sulfate ion
  • NA · Sodium ion
  • ACT · Acetate ion
  • GOL · Glycerol
  • CL · Chloride ion
  • CIT · Citric acid

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