UniProt P01008
P01008
P01008 (UniProt P01008): 54 experimental structures and 1 predicted model on GenesisL1. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P01008
- Experimental structures
- 54
- Predicted models
- 1
Structures
55 records of P01008 in the MolNFT archive: 54 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1ANT | Biological implications of a 3 ångströms structure of dimeric antithrombin | x-ray diffraction | L, I | — | — |
| 1ANT | Biological implications of a 3 ångströms structure of dimeric antithrombin | x-ray diffraction | L, I | — | — |
| 1ATH | The intact and cleaved human antithrombin III complex as a model for serpin-proteinase interactions | x-ray diffraction | A, B | — | — |
| 1ATH | The intact and cleaved human antithrombin III complex as a model for serpin-proteinase interactions | x-ray diffraction | A, B | — | — |
| 1AZX | ANTITHROMBIN/PENTASACCHARIDE complex | x-ray diffraction | I, L | — | — |
| 1AZX | ANTITHROMBIN/PENTASACCHARIDE complex | x-ray diffraction | I, L | — | — |
| 1BR8 | Implications for function and therapy of a 2.9A structure of binary-complexed antithrombin | x-ray diffraction | L, I | — | — |
| 1BR8 | Implications for function and therapy of a 2.9A structure of binary-complexed antithrombin | x-ray diffraction | L, I | — | — |
| 1DZG | N135Q-S380C-antithrombin-III | x-ray diffraction | I, L | — | — |
| 1DZG | N135Q-S380C-antithrombin-III | x-ray diffraction | I, L | — | — |
| 1DZH | P14-fluorescein-N135Q-S380C-antithrombin-III | x-ray diffraction | I, L | — | — |
| 1DZH | P14-fluorescein-N135Q-S380C-antithrombin-III | x-ray diffraction | I, L | — | — |
| 1E03 | Plasma alpha antithrombin-III and pentasaccharide | x-ray diffraction | I, L | — | — |
| 1E03 | Plasma alpha antithrombin-III and pentasaccharide | x-ray diffraction | I, L | — | — |
| 1E04 | Plasma beta antithrombin-III | x-ray diffraction | I, L | — | — |
| 1E04 | Plasma beta antithrombin-III | x-ray diffraction | I, L | — | — |
| 1E05 | Plasma alpha antithrombin-III | x-ray diffraction | I, L | — | — |
| 1E05 | Plasma alpha antithrombin-III | x-ray diffraction | I, L | — | — |
| 1JVQ | Crystal structure at 2.6A of the ternary complex between antithrombin, a P14-P8 reactive loop… | x-ray diffraction | L, I | — | — |
| 1JVQ | Crystal structure at 2.6A of the ternary complex between antithrombin, a P14-P8 reactive loop… | x-ray diffraction | L, I | — | — |
| 1LK6 | Structure of dimeric antithrombin complexed with a P14-P9 reactive loop peptide and an exogenous… | x-ray diffraction | L, I | — | — |
| 1LK6 | Structure of dimeric antithrombin complexed with a P14-P9 reactive loop peptide and an exogenous… | x-ray diffraction | L, I | — | — |
| 1NQ9 | Crystal Structure of Antithrombin in the Pentasaccharide-Bound Intermediate State | x-ray diffraction | I, L | — | — |
| 1NQ9 | Crystal structure of antithrombin in the pentasaccharide-bound intermediate state | x-ray diffraction | I, L | — | — |
| 1OYH | Crystal Structure of P13 Alanine Variant of Antithrombin | x-ray diffraction | I, L | — | — |
| 1OYH | Crystal structure of P13 alanine variant of antithrombin | x-ray diffraction | I, L | — | — |
| 1R1L | Structure of dimeric antithrombin complexed with a P14-P9 reactive loop peptide and an exogenous… | x-ray diffraction | L, I | — | — |
| 1R1L | Structure of dimeric antithrombin complexed with a P14-P9 reactive loop peptide and an exogenous… | x-ray diffraction | L, I | — | — |
| 1SR5 | Antithrombin-anhydrothrombin-heparin ternary complex structure | x-ray diffraction | A | — | — |
| 1SR5 | Antithrombin-anhydrothrombin-heparin ternary complex structure | x-ray diffraction | A | — | — |
| 1T1F | Crystal Structure of Native Antithrombin in its Monomeric Form | x-ray diffraction | A, B, C | — | — |
| 1T1F | Crystal structure of native antithrombin in its monomeric form | x-ray diffraction | A, B, C | — | — |
| 1TB6 | 2.5A Crystal Structure of the Antithrombin-Thrombin-Heparin Ternary Complex | x-ray diffraction | I | — | — |
| 1TB6 | 2.5A crystal structure of the antithrombin-thrombin-heparin ternary complex | x-ray diffraction | I | — | — |
| 2ANT | The 2.6 a structure of antithrombin indicates a conformational change at the heparin binding site | x-ray diffraction | L, I | — | — |
| 2ANT | The 2.6 a structure of antithrombin indicates a conformational change at the heparin binding site | x-ray diffraction | L, I | — | — |
| 2B4X | Crystal Structure of Antithrombin-III | x-ray diffraction | I, L | — | — |
| 2B4X | Crystal structure of antithrombin-III | x-ray diffraction | I, L | — | — |
| 2B5T | 2.1 Angstrom structure of a nonproductive complex between antithrombin, synthetic heparin mimetic… | x-ray diffraction | I | — | — |
| 2B5T | 2.1 ångström structure of a nonproductive complex between antithrombin, synthetic heparin mimetic… | x-ray diffraction | I | — | — |
| 2BEH | Crystal structure of antithrombin variant S137A/V317C/T401C with plasma latent antithrombin | x-ray diffraction | I, L | — | — |
| 2BEH | Crystal structure of antithrombin variant S137A/V317C/T401C with plasma latent antithrombin | x-ray diffraction | I, L | — | — |
| 2GD4 | Crystal Structure of the Antithrombin-S195A Factor Xa-Pentasaccharide Complex | x-ray diffraction | I, C | — | — |
| 2GD4 | Crystal structure of the antithrombin-S195A factor xa-pentasaccharide complex | x-ray diffraction | I, C | — | — |
| 2HIJ | Crystal Structure of P14 Alanine Variant of Antithrombin | x-ray diffraction | I, L | — | — |
| 2HIJ | Crystal structure of P14 alanine variant of antithrombin | x-ray diffraction | I, L | — | — |
| 2ZNH | Crystal Structure of a Domain-Swapped Serpin Dimer | x-ray diffraction | A, B | — | — |
| 2ZNH | Crystal structure of a domain-swapped serpin dimer | x-ray diffraction | A, B | — | — |
| 3EVJ | Intermediate structure of antithrombin bound to the natural pentasaccharide | x-ray diffraction | I, L | — | — |
| 3EVJ | Intermediate structure of antithrombin bound to the natural pentasaccharide | x-ray diffraction | I, L | — | — |
| 3KCG | Crystal structure of the antithrombin-factor IXa-pentasaccharide complex | x-ray diffraction | I | — | — |
| 3KCG | Crystal structure of the antithrombin-factor ixa-pentasaccharide complex | x-ray diffraction | I | — | — |
| 4EB1 | Hyperstable in-frame insertion variant of antithrombin | x-ray diffraction | I, L | — | — |
| 4EB1 | Hyperstable in-frame insertion variant of antithrombin | x-ray diffraction | I, L | — | — |
| P01008 | AlphaFold monomer V2.0 prediction for antithrombin-III (P01008) | predicted | A | — | — |
Experiment against prediction
- 3KCG chain I against the predicted model P01008: TM-score 0.99, RMSD 0.75 Å
- 3KCG chain I against the predicted model P01008: TM-score 0.99, RMSD 0.75 Å
- 1SR5 chain A against the predicted model P01008: TM-score 0.98, RMSD 1.22 Å
- 1SR5 chain A against the predicted model P01008: TM-score 0.98, RMSD 1.22 Å
- 1TB6 chain I against the predicted model P01008: TM-score 0.97, RMSD 1.54 Å
- 1TB6 chain I against the predicted model P01008: TM-score 0.97, RMSD 1.54 Å
- 2GD4 chain C against the predicted model P01008: TM-score 0.97, RMSD 1.50 Å
- 2GD4 chain C against the predicted model P01008: TM-score 0.97, RMSD 1.50 Å
- 2GD4 chain I against the predicted model P01008: TM-score 0.97, RMSD 1.50 Å
- 2GD4 chain I against the predicted model P01008: TM-score 0.97, RMSD 1.50 Å
Elsewhere
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