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MolNFT v1 · #172178 · protein + RNA

Structure of a yeast ABCE1-bound 48S initiation complex

6ZU9: “Structure of a yeast ABCE1-bound 48S initiation complex”. Electron microscopy, 5 ligands (SF4, ADP, ATP). MolNFT v1 #172178 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6ZU9
Type
protein + RNA
Length
9,699 residues
Chains
44
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P32905, P33442, P25443, P0CX35, P0CX37, P26786, P0CX39, O13516, P0CX47, P05756, P06367, P0C0V8, P0C0W1, P0CX29, P0CX31, P39938, P35997, P0CX33, Q01855, P05750, A0A1L4AA68, Q08745, P48589, P0CX51, P02407, P0CX55, P07280, P38701, Q3E792, P41057, P05759, P38011, P0C0X0, P40217, Q04067, P38431, P38249, P06103, P32497, P38912, Q03195
Ligands
SF4, ADP, ATP, MG, ZN

Structure

electron microscopy · 44 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
2—rna1771——
P—protein206—P32905
Q—protein226—P33442
R—protein216—P25443
S—protein258—P0CX35
T—protein228—P0CX37
U—protein184—P26786
V—protein187—P0CX39
W—protein184—O13516
X—protein142—P0CX47
Y—protein150—P05756
Z—protein127—P06367
a—protein87—P0C0V8
b—protein129—P0C0W1
c—protein144—P0CX29
d—protein134—P0CX31
e—protein97—P39938
f—protein81—P35997
g—protein53—P0CX33
E—protein117—Q01855
B—protein222—P05750
C—protein206—A0A1L4AA68
D—protein92—Q08745
F—protein121—P48589
H—protein141—P0CX51
I—protein121—P02407
J—protein145—P0CX55
K—protein143—P07280
L—protein100—P38701
M—protein82—Q3E792
N—protein53—P41057
O—protein73—P05759
h—protein312—P38011
i—protein63—P0C0X0
l—protein330—P40217
r—protein53—Q04067
1—rna75——
m—protein147—P38431
o—protein529—P38249
p—protein646—P06103
q—protein636—P32497
3—rna8——
A—protein101—P38912
k—protein579—Q03195

Ligands and binding sites

  • SF4 · Iron/sulfur cluster · ligand · 2 copies · chains k
  • ADP · Adenosine-5'-diphosphate · ligand · chains k
  • ATP · Adenosine-5'-triphosphate · ligand · chains k
  • MG · Magnesium ion · metal · 4 copies · chains 2, S, C, k
  • ZN · Zinc ion · metal · 3 copies · chains N, O, m

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6ZU9 · Structure of a yeast ABCE1-bound 48S initiation complex · the same entry in another collection · chain Y against Y, TM-score 1.00

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