UniProt P38912
Eukaryotic translation initiation factor 1A (P38912)
Eukaryotic translation initiation factor 1A (UniProt P38912): 19 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P38912
- Protein
- Eukaryotic translation initiation factor 1A
- Experimental structures
- 19
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 3 · 3 records with a druggable one
Structures
20 records of P38912 in the MolNFT archive: 19 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3J80 | CryoEM structure of 40S-eIF1-eIF1A preinitiation complex | electron microscopy | i | — | — |
| 3J80 | Cryoem structure of 40S-EIF1-EIF1A preinitiation complex | electron microscopy | i | — | — |
| 3J81 | CryoEM structure of a partial yeast 48S preinitiation complex | electron microscopy | i | — | — |
| 3J81 | Cryoem structure of a partial yeast 48S preinitiation complex | electron microscopy | i | — | — |
| 3JAM | CryoEM structure of 40S-eIF1A-eIF1 complex from yeast | electron microscopy | i | — | — |
| 3JAM | Cryoem structure of 40S-EIF1A-EIF1 complex from yeast | electron microscopy | i | — | — |
| 3JAP | Structure of a partial yeast 48S preinitiation complex in closed conformation | electron microscopy | i | — | — |
| 3JAP | Structure of a partial yeast 48S preinitiation complex in closed conformation | electron microscopy | i | — | — |
| 3JAQ | Structure of a partial yeast 48S preinitiation complex in open conformation | electron microscopy | i | — | — |
| 3WBK | crystal structure analysis of eukaryotic translation initiation factor 5B and 1A complex | x-ray diffraction | C | — | — |
| 3WBK | Crystal structure analysis of eukaryotic translation initiation factor 5B and 1A complex | x-ray diffraction | C | — | — |
| 6GSM | Structure of a partial yeast 48S preinitiation complex in open conformation. | electron microscopy | i | — | — |
| 6ZCE | Structure of a yeast ABCE1-bound 43S pre-initiation complex | electron microscopy | i | — | — |
| 6ZU9 | Structure of a yeast ABCE1-bound 48S initiation complex | electron microscopy | A | — | — |
| 6ZU9 | Structure of a yeast ABCE1-bound 48S initiation complex | electron microscopy | A | — | — |
| 8RW1 | Structure of a yeast 48S-AUC preinitiation complex in closed conformation | electron microscopy | i | MG | 1 (best 0.85) |
| 8S8D | Structure of a yeast 48S-AUC preinitiation complex in closed conformation (model py48S-AUC-2) | electron microscopy | i | MG | 1 (best 0.87) |
| 8S8H | Structure of a yeast 48S-AUC preinitiation complex in closed conformation (model py48S-AUC-2.2) | electron microscopy | i | MG | — |
| 8S8J | Structure of a yeast 48S-AUC preinitiation complex in closed conformation (model py48S-AUC-eIF5) | electron microscopy | i | MG | 1 (best 0.87) |
| P38912 | AlphaFold monomer V2.0 prediction for eukaryotic translation initiation factor 1A (P38912) | predicted | A | — | — |
Ligands
- MG · Magnesium ion · in 4 records
Experiment against prediction
- 3JAM chain i against the predicted model P38912: TM-score 0.94, RMSD 0.94 Å
- 3JAM chain i against the predicted model P38912: TM-score 0.94, RMSD 0.94 Å
- 8RW1 chain i against the predicted model P38912: TM-score 0.94, RMSD 1.01 Å
- 3J80 chain i against the predicted model P38912: TM-score 0.94, RMSD 1.02 Å
- 3J80 chain i against the predicted model P38912: TM-score 0.94, RMSD 1.02 Å
- 8S8H chain i against the predicted model P38912: TM-score 0.93, RMSD 1.05 Å
- 3JAQ chain i against the predicted model P38912: TM-score 0.92, RMSD 1.14 Å
- 8S8J chain i against the predicted model P38912: TM-score 0.92, RMSD 1.16 Å
- 6ZCE chain i against the predicted model P38912: TM-score 0.90, RMSD 1.15 Å
- 6ZU9 chain A against the predicted model P38912: TM-score 0.90, RMSD 1.36 Å
Elsewhere
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