UniProt P40217
Eukaryotic translation initiation factor 3 subunit I (P40217)
Eukaryotic translation initiation factor 3 subunit I (UniProt P40217): 11 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P40217
- Protein
- Eukaryotic translation initiation factor 3 subunit I
- Experimental structures
- 11
- Predicted models
- 1
- Pockets
- 1 · 1 record with a druggable one
Structures
12 records of P40217 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3JAP | Structure of a partial yeast 48S preinitiation complex in closed conformation | electron microscopy | q | — | — |
| 3JAP | Structure of a partial yeast 48S preinitiation complex in closed conformation | electron microscopy | q | — | — |
| 3JAQ | Structure of a partial yeast 48S preinitiation complex in open conformation | electron microscopy | q | — | — |
| 3ZWL | Structure of eukaryotic translation initiation factor eIF3i complex with eIF3b C-terminus (655-700) | x-ray diffraction | B, D | — | — |
| 3ZWL | Structure of eukaryotic translation initiation factor EIF3I complex with EIF3B C-terminus (655-700) | x-ray diffraction | B, D | — | — |
| 5A5U | Structure of mammalian eIF3 in the context of the 43S preinitiation complex | electron microscopy | I | — | — |
| 5A5U | Structure of mammalian EIF3 in the context of the 43S preinitiation complex | electron microscopy | I | — | — |
| 6GSM | Structure of a partial yeast 48S preinitiation complex in open conformation. | electron microscopy | s | — | — |
| 6ZCE | Structure of a yeast ABCE1-bound 43S pre-initiation complex | electron microscopy | l | — | — |
| 6ZU9 | Structure of a yeast ABCE1-bound 48S initiation complex | electron microscopy | l | — | 1 (best 0.80) |
| 6ZU9 | Structure of a yeast ABCE1-bound 48S initiation complex | electron microscopy | l | — | — |
| P40217 | AlphaFold monomer V2.0 prediction for eukaryotic translation initiation factor 3 subunit I (P40217) | predicted | A | — | — |
Experiment against prediction
- 6GSM chain s against the predicted model P40217: TM-score 0.99, RMSD 0.68 Å
- 6ZCE chain l against the predicted model P40217: TM-score 0.99, RMSD 0.68 Å
- 6ZU9 chain l against the predicted model P40217: TM-score 0.99, RMSD 0.68 Å
- 6ZU9 chain l against the predicted model P40217: TM-score 0.99, RMSD 0.68 Å
- 5A5U chain I against the predicted model P40217: TM-score 0.98, RMSD 1.24 Å
- 5A5U chain I against the predicted model P40217: TM-score 0.98, RMSD 1.24 Å
- 3JAQ chain q against the predicted model P40217: TM-score 0.97, RMSD 1.38 Å
- 3JAP chain q against the predicted model P40217: TM-score 0.96, RMSD 1.51 Å
- 3JAP chain q against the predicted model P40217: TM-score 0.96, RMSD 1.51 Å
- 3ZWL chain D against the predicted model P40217: TM-score 0.95, RMSD 1.24 Å
Elsewhere
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