UniProt P38431
Eukaryotic translation initiation factor 5 (P38431)
Eukaryotic translation initiation factor 5 (UniProt P38431): 7 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P38431
- Protein
- Eukaryotic translation initiation factor 5
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 3 · 3 records with a druggable one
Structures
8 records of P38431 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2FUL | Crystal Structure of the C-terminal Domain of S. cerevisiae eIF5 | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2FUL | Crystal structure of the C-terminal domain of S. cerevisiae EIF5 | x-ray diffraction | A, B, C, D, E, F | — | — |
| 6FYX | Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C1) | electron microscopy | m | MG, ZN | — |
| 6FYY | Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C2) | electron microscopy | m | MG, ZN | 1 (best 0.84) |
| 6ZU9 | Structure of a yeast ABCE1-bound 48S initiation complex | electron microscopy | m | ZN | 1 (best 0.80) |
| 6ZU9 | Structure of a yeast ABCE1-bound 48S initiation complex | electron microscopy | m | ZN | — |
| 8S8J | Structure of a yeast 48S-AUC preinitiation complex in closed conformation (model py48S-AUC-eIF5) | electron microscopy | m | ZN | 1 (best 0.82) |
| P38431 | AlphaFold monomer V2.0 prediction for eukaryotic translation initiation factor 5 (P38431) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6FYX chain m against the predicted model P38431: TM-score 0.96, RMSD 0.90 Å
- 6ZU9 chain m against the predicted model P38431: TM-score 0.96, RMSD 0.90 Å
- 6ZU9 chain m against the predicted model P38431: TM-score 0.96, RMSD 0.90 Å
- 6FYY chain m against the predicted model P38431: TM-score 0.96, RMSD 0.93 Å
- 2FUL chain E against the predicted model P38431: TM-score 0.94, RMSD 1.72 Å
- 2FUL chain E against the predicted model P38431: TM-score 0.94, RMSD 1.72 Å
- 2FUL chain F against the predicted model P38431: TM-score 0.94, RMSD 1.02 Å
- 2FUL chain F against the predicted model P38431: TM-score 0.94, RMSD 1.02 Å
- 2FUL chain B against the predicted model P38431: TM-score 0.94, RMSD 1.33 Å
- 2FUL chain B against the predicted model P38431: TM-score 0.94, RMSD 1.33 Å
Elsewhere
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