UniProt O13516
40S ribosomal protein S9-A (O13516)
40S ribosomal protein S9-A (UniProt O13516): 180 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 273 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O13516
- Protein
- 40S ribosomal protein S9-A
- Experimental structures
- 180
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 273 · 106 records with a druggable one
Structures
181 records of O13516 in the MolNFT archive: 180 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3J6X | S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 5 degree rotation (Class II) | electron microscopy | S9 | — | — |
| 3J6Y | S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 2 degree rotation (Class I) | electron microscopy | S9 | — | — |
| 3J77 | Structures of yeast 80S ribosome-tRNA complexes in the rotated and non-rotated conformations (Class… | electron microscopy | S9 | — | — |
| 3J78 | Structures of yeast 80S ribosome-tRNA complexes in the rotated and non-rotated conformations (Class… | electron microscopy | S9 | — | — |
| 4U3M | Crystal structure of Anisomycin bound to the yeast 80S ribosome | x-ray diffraction | S9, s9 | — | — |
| 4U3N | Crystal structure of CCA trinucleotide bound to the yeast 80S ribosome | x-ray diffraction | S9, s9 | — | — |
| 4U3U | Crystal structure of Cycloheximide bound to the yeast 80S ribosome | x-ray diffraction | S9, s9 | — | — |
| 4U4N | Crystal structure of Edeine bound to the yeast 80S ribosome | x-ray diffraction | S9, s9 | — | — |
| 4U4O | Crystal structure of Geneticin bound to the yeast 80S ribosome | x-ray diffraction | S9, s9 | — | — |
| 4U4Q | Crystal structure of Homoharringtonine bound to the yeast 80S ribosome | x-ray diffraction | S9, s9 | — | — |
| 4U4R | Crystal structure of Lactimidomycin bound to the yeast 80S ribosome | x-ray diffraction | S9, s9 | — | — |
| 4U4U | Crystal structure of Lycorine bound to the yeast 80S ribosome | x-ray diffraction | S9, s9 | — | — |
| 4U4Y | Crystal structure of Pactamycin bound to the yeast 80S ribosome | x-ray diffraction | S9, s9 | — | — |
| 4U4Z | Crystal structure of Phyllanthoside bound to the yeast 80S ribosome | x-ray diffraction | S9, s9 | — | — |
| 4U50 | Crystal structure of Verrucarin bound to the yeast 80S ribosome | x-ray diffraction | S9, s9 | — | — |
| 4U51 | Crystal structure of Narciclasine bound to the yeast 80S ribosome | x-ray diffraction | S9, s9 | — | — |
| 4U52 | Crystal structure of Nagilactone C bound to the yeast 80S ribosome | x-ray diffraction | S9, s9 | — | — |
| 4U53 | Crystal structure of Deoxynivalenol bound to the yeast 80S ribosome | x-ray diffraction | S9, s9 | — | — |
| 4U55 | Crystal structure of Cryptopleurine bound to the yeast 80S ribosome | x-ray diffraction | S9, s9 | — | — |
| 4U56 | Crystal structure of Blasticidin S bound to the yeast 80S ribosome | x-ray diffraction | S9, s9 | — | — |
| 4U6F | Crystal structure of T-2 toxin bound to the yeast 80S ribosome | x-ray diffraction | S9, s9 | — | — |
| 4V4B | Structure of the ribosomal 80S-eEF2-sordarin complex from yeast obtained by docking atomic models… | electron microscopy | AD | — | — |
| 4V6I | Localization of the small subunit ribosomal proteins into a 6.1 A cryo-EM map of Saccharomyces… | electron microscopy | AC | — | — |
| 4V7R | Yeast 80S ribosome. | x-ray diffraction | AE, CE | — | — |
| 4V88 | The structure of the eukaryotic ribosome at 3.0 A resolution. | x-ray diffraction | AJ, CJ | — | — |
| 4V8Y | Cryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation Complex | electron microscopy | AJ | — | — |
| 4V8Z | Cryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation Complex | electron microscopy | AJ | — | — |
| 5DGF | Complex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA… | x-ray diffraction | S9, s9 | — | 6 (best 0.89) |
| 5DGV | Complex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA… | x-ray diffraction | S9, s9 | — | 4 (best 0.88) |
| 5FCI | Structure of the vacant uL3 W255C mutant 80S yeast ribosome | x-ray diffraction | S9, s9 | OHX, MG | 4 (best 0.89) |
| 5I4L | Crystal structure of Amicoumacin A bound to the yeast 80S ribosome | x-ray diffraction | S9, s9 | OHX | 2 (best 0.88) |
| 5JUO | Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura… | electron microscopy | GB | — | 1 (best 0.88) |
| 5JUP | Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura… | electron microscopy | GB | — | — |
| 5JUS | Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura… | electron microscopy | GB | — | — |
| 5JUT | Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura… | electron microscopy | GB | — | 2 (best 0.88) |
| 5JUU | Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura… | electron microscopy | GB | — | 3 (best 0.89) |
| 5LL6 | Structure of the 40S ABCE1 post-splitting complex in ribosome recycling and translation initiation | electron microscopy | W | — | — |
| 5LL6 | Structure of the 40S ABCE1 post-splitting complex in ribosome recycling and translation initiation | electron microscopy | W | — | — |
| 5LYB | Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA… | x-ray diffraction | S9, s9 | MG, OHX | 3 (best 0.88) |
| 5M1J | Nonstop ribosomal complex bound with Dom34 and Hbs1 | electron microscopy | J2 | — | 2 (best 0.88) |
| 5MC6 | Cryo-EM structure of a native ribosome-Ski2-Ski3-Ski8 complex from S. cerevisiae | electron microscopy | W | — | — |
| 5MEI | Crystal structure of Agelastatin A bound to the 80S ribosome | x-ray diffraction | K, s9 | OHX | — |
| 5NDG | Crystal structure of geneticin (G418) bound to the yeast 80S ribosome | x-ray diffraction | S9, s9 | MG | 2 (best 0.89) |
| 5NDV | Crystal structure of Paromomycin bound to the yeast 80S ribosome | x-ray diffraction | S9, s9 | MG | 1 (best 0.88) |
| 5NDW | Crystal structure of aminoglycoside TC007 bound to the yeast 80S ribosome | x-ray diffraction | S9, s9 | MG, 8UZ | 3 (best 0.89) |
| 5OBM | Crystal structure of Gentamicin bound to the yeast 80S ribosome | x-ray diffraction | S9, s9 | MG, LLL | 4 (best 0.89) |
| 5TGA | Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA… | x-ray diffraction | S9, s9 | OHX, MG | 4 (best 0.88) |
| 5TGM | Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA… | x-ray diffraction | S9, s9 | OHX | 3 (best 0.87) |
| 5TZS | Architecture of the yeast small subunit processome | electron microscopy | 9 | — | — |
| 5TZS | Architecture of the yeast small subunit processome | electron microscopy | 9 | — | — |
| 5WLC | The complete structure of the small subunit processome | electron microscopy | L9 | — | — |
| 5WYJ | Cryo-EM structure of the 90S small subunit pre-ribosome (Dhr1-depleted, Enp1-TAP, state 1) | electron microscopy | SK | — | — |
| 5WYK | Cryo-EM structure of the 90S small subunit pre-ribosome (Mtr4-depleted, Enp1-TAP) | electron microscopy | SK | — | — |
| 6EML | Cryo-EM structure of a late pre-40S ribosomal subunit from Saccharomyces cerevisiae | electron microscopy | W | — | 5 (best 0.87) |
| 6EML | Cryo-EM structure of a late pre-40S ribosomal subunit from saccharomyces cerevisiae | electron microscopy | W | — | — |
| 6FAI | Structure of a eukaryotic cytoplasmic pre-40S ribosomal subunit | electron microscopy | J | — | 5 (best 0.86) |
| 6FAI | Structure of a eukaryotic cytoplasmic pre-40S ribosomal subunit | electron microscopy | J | — | — |
| 6GQ1 | Cryo-EM reconstruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GMPPCP/sordarin) | electron microscopy | z | — | — |
| 6GQB | Cryo-EM reconstruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GDP+AlF4/sordarin) | electron microscopy | z | — | — |
| 6GQV | Cryo-EM recosntruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GMPPCP) | electron microscopy | z | — | — |
121 records more on the page itself.
Ligands
- MG · Magnesium ion · in 15 records
- OHX · osmium (III) hexammine · in 8 records
- 8UZ · Tc007 · in 1 record
- LLL · (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-diamino-3-((2R, 3R,6S)-3-amino-6-(aminomethyl)-tetrahydro-2H-pyran-2-yloxy)-2-hydroxycyclohexyloxy)-5-methyl-4-(methylamino)-tetrahydro-2H-pyran-3,5-diol · in 1 record
Experiment against prediction
- 6FAI chain J against the predicted model O13516: TM-score 0.99, RMSD 0.49 Å
- 6T4Q chain SJ against the predicted model O13516: TM-score 0.99, RMSD 0.51 Å
- 6SNT chain J against the predicted model O13516: TM-score 0.99, RMSD 0.54 Å
- 6RBD chain J against the predicted model O13516: TM-score 0.99, RMSD 0.55 Å
- 7A1G chain W against the predicted model O13516: TM-score 0.99, RMSD 0.56 Å
- 6TB3 chain W against the predicted model O13516: TM-score 0.99, RMSD 0.56 Å
- 6T7I chain SJ against the predicted model O13516: TM-score 0.99, RMSD 0.60 Å
- 6T7T chain SJ against the predicted model O13516: TM-score 0.99, RMSD 0.60 Å
- 5TZS chain 9 against the predicted model O13516: TM-score 0.99, RMSD 0.63 Å
- 4U55 chain S9 against the predicted model O13516: TM-score 0.98, RMSD 0.70 Å
Elsewhere
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